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  Selvakumar Ramalingam,N. V. Mahalakshmi RSC Adv. 2020 10 4274
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• Solvents and Organic Chemicals Organic Compounds Lipids and lipid-like molecules Fatty Acyls Fatty acid methyl esters
• Solvents and Organic Chemicals Organic Compounds Lipids and lipid-like molecules Fatty Acyls Fatty acid esters Fatty acid methyl esters
• Solvents and Organic Chemicals Organic Compounds Acids/Esters

Methyl Tetracosanoate (CAS No. 2442-49-1): An Overview of Its Properties, Applications, and Recent Research

Methyl tetracosanoate (CAS No. 2442-49-1) is a long-chain fatty acid ester that has garnered significant attention in various scientific and industrial applications. This compound, also known as methyl tetracosanoate or methyl 24:0, is a derivative of tetracosanoic acid (lignoceric acid) and methanol. Its unique chemical structure and properties make it a valuable component in fields such as pharmaceuticals, cosmetics, and materials science.

The chemical formula of methyl tetracosanoate is C₂₅H₅₀O₂, and it has a molecular weight of 378.66 g/mol. This compound is characterized by its long hydrocarbon chain, which imparts several desirable properties, including high melting point, low volatility, and excellent stability. These characteristics make it suitable for a wide range of applications where thermal and chemical stability are crucial.

In the pharmaceutical industry, methyl tetracosanoate has been explored for its potential as a drug delivery vehicle. Its ability to form stable micelles and liposomes allows for the encapsulation and controlled release of active pharmaceutical ingredients (APIs). Recent studies have shown that methyl tetracosanoate-based formulations can enhance the bioavailability and therapeutic efficacy of various drugs, particularly those with poor solubility or stability issues.

In the field of cosmetics, methyl tetracosanoate is valued for its emollient properties and its ability to improve the texture and feel of skincare products. It can be used as a moisturizing agent in creams, lotions, and serums, providing a smooth and non-greasy finish. Additionally, its high melting point makes it suitable for use in solid formulations such as lip balms and deodorants.

Recent research has also highlighted the potential of methyl tetracosanoate in materials science. Its long hydrocarbon chain can be utilized to modify the surface properties of various materials, enhancing their hydrophobicity and lubricity. This makes it useful in applications such as coatings, lubricants, and adhesives. For example, a study published in the Journal of Applied Polymer Science demonstrated that methyl tetracosanoate-modified polymers exhibited improved mechanical properties and reduced friction coefficients.

The synthesis of methyl tetracosanoate typically involves the esterification reaction between tetracosanoic acid and methanol in the presence of an acid catalyst. The reaction conditions can be optimized to achieve high yields and purity levels. Industrial-scale production methods often employ continuous flow reactors to ensure consistent quality and efficiency.

In terms of safety and environmental impact, methyl tetracosanoate is generally considered to be non-toxic and biodegradable. However, it is important to handle this compound with care to avoid skin contact or inhalation of vapors. Proper storage conditions should be maintained to prevent degradation or contamination.

To ensure the quality and consistency of methyl tetracosanoate, various analytical techniques are employed during its production and characterization. Gas chromatography-mass spectrometry (GC-MS) is commonly used to determine the purity and composition of the final product. Other techniques such as nuclear magnetic resonance (NMR) spectroscopy and Fourier-transform infrared (FTIR) spectroscopy provide additional insights into the molecular structure and functional groups.

In conclusion, methyl tetracosanoate (CAS No. 2442-49-1) is a versatile compound with a wide range of applications in pharmaceuticals, cosmetics, and materials science. Its unique chemical properties make it an attractive choice for formulators seeking to enhance the performance of their products. Ongoing research continues to uncover new potential uses for this compound, further solidifying its importance in various scientific disciplines.

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• 106-79-6(Dimethyl sebacate)
• 3946-32-5(Monomethyl Suberate)
• 167388-13-8(Methyl Stearate-1-13C)
• 112-39-0(Methyl palmitate)
• 61788-59-8(Coconut fatty acid methyl ester)
• 1472-93-1(Dimethyl octadecanedioate)
• 110-42-9(Methyl decanoate)
• 111-11-5(Methyl octanoate)
• 95481-62-2(Dibasic ester)