• 1. Dual pH-responsive micelles with both charge-conversional property and hydrophobic–hydrophilic transition for effective cellular uptake and intracellular drug release
  Shuai Li,Zhouxiang Zhao,Wei Wu,Chunmei Ding,Jianshu Li Polym. Chem. 2016 7 2202
• 2. Tumor-targeted aggregation of pH-sensitive nanocarriers for enhanced retention and rapid intracellular drug release
  Wei Wu,Qiujing Zhang,Jiantao Wang,Miao Chen,Shuai Li,Zaifu Lin,Jianshu Li Polym. Chem. 2014 5 5668
• 3. Cationic and reactive primary amine-stabilised nanoparticles via RAFT aqueous dispersion polymerisation
  M. Williams,N. J. W. Penfold,S. P. Armes Polym. Chem. 2016 7 384
• 4. Substrate-independent, Schiff base interactions to fabricate lysine-functionalized surfaces with fibrinolytic activity
  Xiao-Wen Lu,Wei Liu,Zhao-Qiang Wu,Xin-Hong Xiong,Qi Liu,Wen-Jun Zhan,Hong Chen J. Mater. Chem. B 2016 4 1458
• 5. A novel family of biodegradable hybrid hydrogels from arginine-based poly(ester amide) and hyaluronic acid precursors
  De-Qun Wu,Jun Wu,Chih-Chang Chu Soft Matter 2013 9 3965

• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Carboxylic acid esters
• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Carboxylic acid derivatives Carboxylic acid esters

Professional Introduction to 2-Aminoethyl methacrylate hydrochloride (CAS No. 2420-94-2)

2-Aminoethyl methacrylate hydrochloride, with the chemical identifier CAS No. 2420-94-2, is a versatile monomer widely utilized in the field of polymer chemistry and biomedical applications. This compound, characterized by its hydrochloride salt form, exhibits remarkable reactivity due to the presence of both a methacrylate functional group and an aminoethyl side chain. The unique structural properties of this molecule make it a valuable building block for the synthesis of advanced materials, including hydrogels, polymers, and drug delivery systems.

The reactivity of the methacrylate group allows for facile polymerization via free-radical initiated reactions, making it a preferred choice for producing cross-linked networks with tunable mechanical and chemical properties. In recent years, researchers have leveraged the bifunctional nature of 2-Aminoethyl methacrylate hydrochloride to develop innovative biomedical materials. For instance, its incorporation into hydrogel matrices has enabled the creation of scaffolds that mimic the extracellular matrix (ECM) of tissues, facilitating cell adhesion, proliferation, and differentiation.

One of the most compelling applications of 2-Aminoethyl methacrylate hydrochloride is in the realm of drug delivery systems. The aminoethyl group provides a site for conjugation with therapeutic agents, allowing for controlled release mechanisms that enhance bioavailability and reduce side effects. Recent studies have demonstrated its use in designing stimuli-responsive hydrogels that release drugs in response to pH changes or enzymatic activity, thereby improving targeted therapy in oncology and infectious diseases.

Furthermore, the adaptability of CAS No. 2420-94-2 has been exploited in the development of smart polymers for regenerative medicine. By functionalizing the monomer with bioactive molecules or integrating it into 3D bioprinting formulations, researchers have created materials capable of guiding tissue regeneration. These advancements underscore the significance of 2-Aminoethyl methacrylate hydrochloride as a cornerstone in modern material science and pharmaceutical innovation.

The chemical stability and solubility profile of this compound also make it suitable for industrial-scale applications. Its compatibility with various solvents and its ability to undergo controlled polymerization processes ensure consistent quality in manufacturing. As the demand for high-performance materials grows, CAS No. 2420-94-2 continues to be a critical component in research and development initiatives across multiple industries.

In conclusion, 2-Aminoethyl methacrylate hydrochloride represents a pivotal compound in advanced material engineering and biomedical applications. Its unique structural features enable diverse functionalities, from polymerization to drug delivery and tissue engineering. With ongoing research exploring novel applications and optimization strategies, this monomer is poised to remain at the forefront of scientific innovation.

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