• 1. Establishing plasmon contribution to chemical reactions: alkoxyamines as a thermal probe?
  Olga Guselnikova,Gérard Audran,Jean-Patrick Joly,Andrii Trelin,Evgeny V. Tretyakov,Vaclav Svorcik,Oleksiy Lyutakov,Sylvain R. A. Marque Chem. Sci., 2021,12, 4154-4161
• 2. Excitation energies from ground-state density-functionals by means of generator coordinates
  A. B. F. da Silva,K. Capelle Phys. Chem. Chem. Phys., 2009,11, 4564-4569
• 3. Enabling high-throughput single-animal gene-expression studies with molecular and micro-scale technologies
  Jason Wan Lab Chip, 2020,20, 4528-4538
• 4. Emulsion technologies for multicellular tumour spheroid radiation assays?
  Kay S. McMillan,Anthony G. McCluskey,Annette Sorensen,Marie Boyd,Michele Zagnoni Analyst, 2016,141, 100-110
• 5. Evolution of calcium phosphate precipitation in hanging drop vapor diffusion by in situRaman microspectroscopy
  Gloria Belén Ramírez-Rodríguez,José Manuel Delgado-López,Jaime Gómez-Morales CrystEngComm, 2013,15, 2206-2212

• Solvents and Organic Chemicals Organic Compounds Lipids and lipid-like molecules Fatty Acyls Fatty acids and conjugates

Comprehensive Analysis of 3-Dimethylphosphorylbutanoic Acid (CAS No. 2416235-63-5): Properties, Applications, and Industry Trends

3-Dimethylphosphorylbutanoic acid (CAS No. 2416235-63-5) is an organophosphorus compound gaining attention in pharmaceutical and agrochemical research due to its unique structural and functional properties. This article explores its molecular characteristics, synthesis pathways, and emerging applications while addressing frequently searched queries like "3-Dimethylphosphorylbutanoic acid uses" and "CAS 2416235-63-5 safety data."

The compound features a phosphoryl group (–P=O) bonded to a butanoic acid backbone, with two methyl groups enhancing its lipophilicity. This structure enables versatile reactivity, making it valuable for designing prodrugs or enzyme inhibitors. Researchers often search for "phosphorylated carboxylic acid derivatives" or "P-containing bioactive molecules," reflecting growing interest in its role in drug discovery.

Current synthetic methods for 3-Dimethylphosphorylbutanoic acid involve phosphorylation of 3-hydroxybutanoate derivatives or Michaelis-Arbuzov reactions. Optimized protocols aim to improve yield (>85%) and purity (>98%), addressing lab-scale challenges highlighted in queries like "CAS 2416235-63-5 synthesis protocol." Green chemistry principles are increasingly applied, aligning with trends in sustainable synthesis.

In pharmaceuticals, this compound serves as a precursor for kinase-targeting molecules, correlating with searches for "phosphoryl butanoic acid drug candidates." Its agrochemical potential includes crop protection agents, responding to demand for "eco-friendly phosphorus pesticides." These applications leverage its balanced polarity and metabolic stability.

Analytical characterization employs ³¹P NMR (δ ~30 ppm) and LC-MS (MW 180.12 g/mol), with HPLC purity assays (>95%) being critical for industrial standards. Such data addresses technical queries like "3-Dimethylphosphorylbutanoic acid spectral data" frequently encountered in quality control workflows.

Regulatory assessments confirm its non-hazardous classification under standard conditions, though proper PPE (gloves, goggles) is recommended during handling. This aligns with searches for "CAS 2416235-63-5 handling precautions" while ensuring compliance with global chemical regulations.

The market for phosphorylated specialty chemicals is projected to grow at 6.8% CAGR (2023-2030), driven by demand in precision agriculture and targeted therapeutics. Strategic partnerships between academic labs and manufacturers are accelerating commercialization, as seen in patent filings for derivatives of 2416235-63-5.

Future research directions include exploring its use in bioconjugation (addressing "protein-phosphoryl linker chemistry" searches) and metal-chelating materials. Continuous process intensification and AI-assisted molecular modeling are expected to further optimize its production and application scope.

• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)