Cas no 24152-95-2 (2-Oxo-2-pyrrolidin-1-ylethanamine)

2-Oxo-2-pyrrolidin-1-ylethanamine is a versatile organic compound featuring a pyrrolidinyl moiety linked to an ethanamine backbone via a carbonyl group. This structure imparts unique reactivity, making it valuable as an intermediate in pharmaceutical and agrochemical synthesis. Its pyrrolidine ring enhances conformational flexibility, while the carbonyl and amine functionalities offer sites for further derivatization. The compound is particularly useful in the development of nootropic agents and CNS-targeted molecules due to its ability to cross the blood-brain barrier. High purity grades ensure consistent performance in research and industrial applications. Stability under standard conditions and compatibility with common solvents further underscore its utility in synthetic chemistry.
2-Oxo-2-pyrrolidin-1-ylethanamine structure
24152-95-2 structure
Product Name:2-Oxo-2-pyrrolidin-1-ylethanamine
CAS No:24152-95-2
MF:C6H12N2O
MW:128.172281265259
MDL:MFCD08060127
CID:851129
PubChem ID:11205761
Update Time:2025-05-24

2-Oxo-2-pyrrolidin-1-ylethanamine Chemical and Physical Properties

Names and Identifiers

    • 2-Amino-1-(pyrrolidin-1-yl)ethanone
    • ethanone, 2-amino-1-(1-pyrrolidinyl)-
    • LogP
    • 2-amino-1-pyrrolidin-1-ylethanone
    • 2-OXO-2-PYRROLIDIN-1-YLETHANAMINE
    • 1-glycyl-pyrrolidine
    • DTXSID90458612
    • 2-amino-1-pyrrolidin-1-yl-ethanone
    • AKOS000206326
    • 24152-95-2
    • DA-07778
    • SCHEMBL914046
    • BBL030890
    • STK988509
    • BS-13027
    • glycyl-pyrrolidine
    • 2-Amino-1-(1-pyrrolidinyl)ethanone
    • MFCD08060127
    • EN300-26664
    • 2-amino-1-(pyrrolidin-1-yl)ethan-1-one
    • ALBB-018622
    • SY168549
    • CHEMBL97025
    • 2-oxo-2-(1-pyrrolidinyl)ethanamine
    • CS-0435631
    • E84114
    • SJNAQBNIUKINQH-UHFFFAOYSA-N
    • BDBM50118931
    • 2-Oxo-2-pyrrolidin-1-ylethanamine
    • MDL: MFCD08060127
    • Inchi: 1S/C6H12N2O/c7-5-6(9)8-3-1-2-4-8/h1-5,7H2
    • InChI Key: SJNAQBNIUKINQH-UHFFFAOYSA-N
    • SMILES: O=C(CN)N1CCCC1

Computed Properties

  • Exact Mass: 128.09500
  • Monoisotopic Mass: 128.094963011g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 9
  • Rotatable Bond Count: 2
  • Complexity: 108
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: -0.7
  • Topological Polar Surface Area: 46.3?2

Experimental Properties

  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 262.1±23.0 °C at 760 mmHg
  • Flash Point: 112.3±22.6 °C
  • PSA: 46.33000
  • LogP: 0.20570
  • Vapor Pressure: 0.0±0.5 mmHg at 25°C

2-Oxo-2-pyrrolidin-1-ylethanamine Security Information

2-Oxo-2-pyrrolidin-1-ylethanamine Customs Data

  • HS CODE:2933990090
  • Customs Data:

    China Customs Code:

    2933990090

    Overview:

    2933990090. Other heterocyclic compounds containing only nitrogen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Additional information on 2-Oxo-2-pyrrolidin-1-ylethanamine

2-Oxo-2-pyrrolidin-1-ylethanamine (CAS No. 24152-95-2): A Comprehensive Overview

The compound 2-Oxo-2-pyrrolidin-1-ylethanamine, identified by the CAS number 24152-95-2, is a significant molecule in the field of organic chemistry and pharmacology. This compound has garnered attention due to its unique structural properties and potential applications in drug development. The molecule consists of a pyrrolidine ring fused with an ethanamine group, creating a structure that exhibits interesting chemical reactivity and biological activity.

Recent studies have highlighted the importance of 2-Oxo-2-pyrrolidin-1-ylethanamine in the synthesis of bioactive compounds. Researchers have explored its role as an intermediate in the construction of complex molecules, particularly those with potential therapeutic applications. For instance, the compound has been utilized in the development of novel antibiotics and anti-inflammatory agents. Its ability to undergo various chemical transformations, such as alkylation and acylation, makes it a versatile building block in organic synthesis.

One of the most notable advancements involving 2-Oxo-2-pyrrolidin-1-ylethanamine is its application in peptide synthesis. The compound's structure allows for efficient coupling reactions, which are crucial in the construction of peptide chains. This has led to its use in the development of peptide-based drugs, such as those targeting cancer and infectious diseases. The integration of this compound into peptide frameworks has significantly enhanced the stability and bioavailability of these therapeutic agents.

In addition to its role in drug development, 2-Oxo-2-pyrrolidin-1-ylethanamine has also been studied for its potential in materials science. Researchers have investigated its ability to form self-assembled structures, which could be utilized in the creation of advanced materials with unique properties. These materials could find applications in fields such as electronics, sensors, and drug delivery systems.

The synthesis of 2-Oxo-2-pyrrolidin-1-ylethanamine has been optimized through various methodologies. Traditional approaches involve the reaction of pyrrolidine derivatives with carbonyl compounds under specific conditions. However, recent advancements have introduced more efficient routes, such as microwave-assisted synthesis and catalytic methods, which reduce reaction times and improve yields. These improvements have made the compound more accessible for large-scale production and research purposes.

From a safety standpoint, 2-Oxo-2-pyrrolidin-1-ylethanamine has been subjected to rigorous testing to ensure its compatibility with biological systems. Studies indicate that the compound exhibits low toxicity when used within recommended limits, making it suitable for applications in pharmaceuticals and other health-related products.

In conclusion, 2-Oxo-2-pyrrolidin-1-ylethanamine (CAS No. 24152-95-) stands as a pivotal molecule in contemporary chemistry and pharmacology. Its versatile structure and wide-ranging applications continue to drive innovation across multiple disciplines. As research progresses, this compound is expected to play an even greater role in the development of novel therapeutic agents and advanced materials.

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