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• Solvents and Organic Chemicals Organic Compounds Amines/Sulfonamides

2-Chloro-5-methoxyaniline (CAS No. 2401-24-3): An Overview of Its Properties, Applications, and Recent Research

2-Chloro-5-methoxyaniline (CAS No. 2401-24-3) is a versatile organic compound with a wide range of applications in the chemical and pharmaceutical industries. This compound is characterized by its unique structure, which includes a chlorine atom and a methoxy group attached to an aniline framework. The combination of these functional groups imparts specific chemical and physical properties that make it valuable in various synthetic processes.

The molecular formula of 2-Chloro-5-methoxyaniline is C₇H₈ClNO, and its molecular weight is approximately 159.60 g/mol. The compound is a white to off-white crystalline solid at room temperature and is slightly soluble in water but highly soluble in organic solvents such as ethanol, acetone, and dichloromethane. These solubility properties are crucial for its use in chemical reactions and formulations.

In the pharmaceutical industry, 2-Chloro-5-methoxyaniline serves as an important intermediate in the synthesis of various drugs and pharmaceuticals. Its reactivity and functional group versatility make it a valuable starting material for the development of new therapeutic agents. Recent research has focused on its potential applications in the synthesis of anti-inflammatory, antiviral, and anticancer drugs.

A study published in the Journal of Medicinal Chemistry highlighted the use of 2-Chloro-5-methoxyaniline in the synthesis of novel anti-inflammatory compounds. The researchers demonstrated that derivatives of this compound exhibited significant anti-inflammatory activity in vitro and in vivo models. This finding underscores the potential of 2-Chloro-5-methoxyaniline as a key intermediate in the development of new therapeutic agents for inflammatory diseases.

In addition to its pharmaceutical applications, 2-Chloro-5-methoxyaniline is also used in the dye and pigment industry. Its unique chemical structure allows it to serve as a precursor for the synthesis of various dyes and pigments with specific color properties. These dyes are widely used in textile, printing, and coating applications due to their excellent colorfastness and stability.

The environmental impact of chemicals like 2-Chloro-5-methoxyaniline is an important consideration in their use and disposal. Recent studies have investigated the biodegradability and ecotoxicity of this compound to ensure its safe use in industrial processes. A study published in the Journal of Environmental Science and Health reported that under controlled conditions, 2-Chloro-5-methoxyaniline exhibits moderate biodegradability, suggesting that appropriate waste management practices can minimize its environmental impact.

Safety is another critical aspect when handling 2-Chloro-5-methoxyaniline. While it is not classified as a hazardous substance under current regulations, proper handling procedures should be followed to ensure worker safety. This includes using personal protective equipment (PPE) such as gloves, goggles, and respiratory protection when working with this compound.

In conclusion, 2-Chloro-5-methoxyaniline (CAS No. 2401-24-3) is a multifaceted compound with significant applications in the pharmaceutical, dye, and pigment industries. Its unique chemical structure and reactivity make it an essential intermediate in various synthetic processes. Ongoing research continues to explore new applications and improve our understanding of its properties, ensuring its continued relevance in modern chemistry.

• 85893-87-4(2-Chloro-3-methoxyaniline hydrochloride)
• 28434-86-8(Benzenamine,4,4'-oxybis[2-chloro-)
• 32829-09-7(2-Chloro-4,5-dimethoxyaniline)
• 85006-21-9(2-Chloro-5-methoxyaniline hydrochloride)
• 98446-49-2(2,4-Dichloro-5-methoxyaniline)
• 113206-03-4(2-Chloro-3-methoxyaniline)
• 16026-77-0(3-Amino-4-chlorophenol)
• 105945-24-2(Benzenamine,3-(4-chlorophenoxy)-)
• 29242-84-0(2-Chloro-4-methoxyaniline)
• 6480-66-6(2,6-Dichloro-4-methoxyaniline)