• 1. An assessment of strategies for the development of solid-state adsorbents for vehicular hydrogen storage
  Mark D. Allendorf,Alauddin Ahmed,Tom Autrey,Jeffrey Camp,Eun Seon Cho,Maciej Haranczyk,Abhi Karkamkar,Di-Jia Liu,Katie R. Meihaus,Iffat H. Nayyar,Roman Nazarov,Donald J. Siegel,Vitalie Stavila,Jeffrey J. Urban,Srimukh Prasad Veccham,Brandon C. Wood Energy Environ. Sci., 2018,11, 2784-2812
• 2. An antimonate pyrochlore (H1.23Sr0.45SbO3.48) for photocatalytic oxidation of benzene: effective oxygen usage and excellent activity?
  Jing Chen,Yu Shao,Danzhen Li J. Mater. Chem. A, 2017,5, 937-941
• 3. An investigation of new infrared nonlinear optical material: BaCdSnSe4, and three new related centrosymmetric compounds: Ba2SnSe4, Mg2GeSe4, and Ba2Ge2S6?
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• 4. An artificial CO-releasing metalloprotein built by histidine-selective metallation?
  Inês S. Albuquerque,Hélia F. Jeremias,Miguel Chaves-Ferreira,Dijana Matak-Vinkovic,Omar Boutureira,Carlos C. Rom?o Chem. Commun., 2015,51, 3993-3996
• 5. An amplified fluorescence detection of T4 polynucleotide kinase activity based on coupled exonuclease III reaction and a graphene oxide platform?
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• Solvents and Organic Chemicals Organic Compounds Phenylpropanoids and polyketides Cinnamic acids and derivatives Cinnamic acids
• Solvents and Organic Chemicals Organic Compounds Acids/Esters

3-(4-Ethoxyphenyl)Prop-2-Enoic Acid: A Comprehensive Overview

3-(4-Ethoxyphenyl)prop-2-enoic acid, also known by its CAS number 2373-79-7, is a compound of significant interest in the fields of organic chemistry and pharmacology. This compound, with its unique structure and properties, has garnered attention due to its potential applications in drug development and as a precursor in various chemical syntheses. The molecule consists of a phenyl ring substituted with an ethoxy group at the para position, connected via a propenoic acid moiety. This structural arrangement imparts distinctive chemical and biological properties, making it a subject of extensive research.

The synthesis of 3-(4-ethoxyphenyl)prop-2-enoic acid typically involves multi-step organic reactions, often starting from readily available aromatic compounds. Recent advancements in catalytic methods have enabled more efficient and environmentally friendly syntheses, which align with the growing demand for sustainable chemical processes. Researchers have explored various catalysts, including transition metal catalysts and enzymes, to optimize the yield and purity of this compound. These developments highlight the importance of green chemistry principles in modern synthetic strategies.

In terms of physical properties, 3-(4-ethoxyphenyl)prop-2-enoic acid exhibits a melting point of approximately 150°C and is sparingly soluble in water but highly soluble in organic solvents such as dichloromethane and ethyl acetate. Its UV-vis spectrum shows strong absorption bands due to the conjugated system formed by the phenyl ring and the propenoic acid group. This characteristic makes it a useful chromophore in dye-sensitized solar cells and other optoelectronic applications.

The biological activity of 3-(4-ethoxyphenyl)prop-2-enoic acid has been extensively studied. Recent research indicates that this compound possesses significant anti-inflammatory properties, attributed to its ability to inhibit cyclooxygenase (COX) enzymes. Additionally, it has shown promise as an antioxidant, capable of neutralizing free radicals and protecting cells from oxidative damage. These findings underscore its potential as a lead compound in the development of novel therapeutic agents for inflammatory diseases and oxidative stress-related disorders.

In the realm of pharmacology, 3-(4-ethoxyphenyl)prop-2-enoic acid has been investigated for its role as a drug delivery agent. Its ability to form stable complexes with metal ions has led to its use in designing targeted drug delivery systems. For instance, researchers have explored its application in encapsulating anticancer drugs, enhancing their bioavailability and reducing systemic toxicity. Such innovations highlight the versatility of this compound in advancing medical treatments.

The application of 3-(4-ethoxyphenyl)prop-2-enoic acid extends beyond medicine into industrial chemistry. It serves as an intermediate in the synthesis of more complex molecules, including agrochemicals and specialty chemicals. Its role as a building block in organic synthesis is further enhanced by its compatibility with various functional groups, making it a valuable asset in combinatorial chemistry.

In conclusion, 3-(4-ethoxyphenyl)prop-2-enoic acid, with its CAS number 2373-79-7, stands out as a multifaceted compound with diverse applications across multiple disciplines. From its synthesis and physical properties to its biological activity and industrial uses, this compound continues to be a focal point for researchers aiming to harness its potential for innovative solutions in health care and beyond.

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