Cas no 2367-25-1 (Crotonic acid,4-fluoro-, methyl ester (8CI))
Crotonic acid, 4-fluoro-, methyl ester (8CI) is a fluorinated ester derivative of crotonic acid, characterized by its incorporation of a fluorine substituent at the 4-position. This modification enhances its reactivity and selectivity in organic synthesis, particularly in applications requiring fluorinated intermediates. The compound is valued for its utility in pharmaceutical and agrochemical research, where fluorinated compounds often exhibit improved metabolic stability and bioavailability. Its ester functionality further facilitates derivatization, making it a versatile building block for fine chemical synthesis. The product is typically handled under controlled conditions due to its reactive nature, ensuring optimal performance in specialized synthetic pathways.
2367-25-1 structure
Product Name:Crotonic acid,4-fluoro-, methyl ester (8CI)
CAS No:2367-25-1
MF:C5H7FO2
MW:118.106285333633
CID:256825
PubChem ID:6433333
Update Time:2025-05-28
Crotonic acid,4-fluoro-, methyl ester (8CI) Chemical and Physical Properties
Names and Identifiers
-
- Crotonic acid,4-fluoro-, methyl ester (8CI)
- methyl (E)-4-fluorobut-2-enoate
- 2-butenoic acid, 4-fluoro-, methyl ester, (2E)-
- Methyl (2E)-4-fluorobut-2-enoate
- Methyl gamma-fluorocrotonate
- CHEMBL3273388
- Crotonic acid, gamma-fluoro-, methyl ester
- EN300-6745279
- AKOS040805016
- TL 1183
- CROTONIC ACID, 4-FLUORO-, METHYL ESTER
- 2367-25-1
-
- Inchi： 1S/C5H7FO2/c1-8-5(7)3-2-4-6/h2-3H,4H2,1H3/b3-2+
- InChI Key： URXNTGHLANVRSX-NSCUHMNNSA-N
- SMILES： FC/C=C/C(=O)OC
Computed Properties
- Exact Mass: 118.04301
- Monoisotopic Mass: 118.043008
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 8
- Rotatable Bond Count: 3
- Complexity: 98.6
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 1
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 26.3
- XLogP3: 0.7
Experimental Properties
- Density: 1.1135 (estimate)
- Boiling Point: 135.6°C at 760 mmHg
- Flash Point: 35.7°C
- Refractive Index: 1.394
- PSA: 26.3
Crotonic acid,4-fluoro-, methyl ester (8CI) Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Enamine | EN300-6745279-0.05g |
methyl (2E)-4-fluorobut-2-enoate |
2367-25-1 | 95% | 0.05g |
$576.0 | 2023-05-30 | |
| Enamine | EN300-6745279-0.1g |
methyl (2E)-4-fluorobut-2-enoate |
2367-25-1 | 95% | 0.1g |
$752.0 | 2023-05-30 | |
| Enamine | EN300-6745279-0.25g |
methyl (2E)-4-fluorobut-2-enoate |
2367-25-1 | 95% | 0.25g |
$1075.0 | 2023-05-30 | |
| Enamine | EN300-6745279-0.5g |
methyl (2E)-4-fluorobut-2-enoate |
2367-25-1 | 95% | 0.5g |
$1692.0 | 2023-05-30 | |
| Enamine | EN300-6745279-1.0g |
methyl (2E)-4-fluorobut-2-enoate |
2367-25-1 | 95% | 1g |
$2168.0 | 2023-05-30 | |
| Enamine | EN300-6745279-2.5g |
methyl (2E)-4-fluorobut-2-enoate |
2367-25-1 | 95% | 2.5g |
$4250.0 | 2023-05-30 | |
| Enamine | EN300-6745279-5.0g |
methyl (2E)-4-fluorobut-2-enoate |
2367-25-1 | 95% | 5g |
$6289.0 | 2023-05-30 | |
| Enamine | EN300-6745279-10.0g |
methyl (2E)-4-fluorobut-2-enoate |
2367-25-1 | 95% | 10g |
$9325.0 | 2023-05-30 | |
| Aaron | AR00BSSH-50mg |
4-Fluoro-2-butenoic acid methyl ester |
2367-25-1 | 95% | 50mg |
$817.00 | 2025-02-14 | |
| Aaron | AR00BSSH-100mg |
4-Fluoro-2-butenoic acid methyl ester |
2367-25-1 | 95% | 100mg |
$1059.00 | 2025-02-14 |
Crotonic acid,4-fluoro-, methyl ester (8CI) Related Literature
-
Gang Pan,Yi-jie Bao,Jie Xu,Tao Liu,Cheng Liu,Yan-yan Qiu,Xiao-jing Shi,Hui Yu,Ting-ting Jia,Xia Yuan,Ze-ting Yuan,Yi-jun Cao RSC Adv., 2016,6, 42109-42119
-
Dan Yang,Yanping Zhou,Xianhong Rui,Jixin Zhu,Ziyang Lu,Eileen Fong,Qingyu Yan RSC Adv., 2013,3, 14960-14962
-
Helga Garcia,Rui Ferreira,Marija Petkovic,Jamie L. Ferguson,Maria C. Leit?o,H. Q. Nimal Gunaratne,Luís Paulo N. Rebelo Green Chem., 2010,12, 367-369
-
Shaun D. Wong,Edward I. Solomon Dalton Trans., 2014,43, 17567-17577
-
5. Excimer emission and magnetoluminescence of radical-based zinc(ii) complexes doped in host crystals?Shojiro Kimura,Tetsuro Kusamoto Chem. Commun., 2020,56, 11195-11198
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