Cas no 2357-33-7 (4-Fluoro-2-(hydroxymethyl)phenol)

4-Fluoro-2-(hydroxymethyl)phenol structure
2357-33-7 structure
Product Name:4-Fluoro-2-(hydroxymethyl)phenol
CAS No:2357-33-7
MF:C7H7FO2
MW:142.127685785294
MDL:MFCD03412237
CID:873430
PubChem ID:10606838
Update Time:2025-04-24

4-Fluoro-2-(hydroxymethyl)phenol Chemical and Physical Properties

Names and Identifiers

    • Fluorohydroxybenzylalcohol
    • 4-Fluoro-2-(hydroxymethyl)phenol
    • BENZENEMETHANOL,5-FLUORO-2-HYDROXY
    • Benzenemethanol, 5-fluoro-2-hydroxy-
    • SCHEMBL1906156
    • MFCD03412237
    • EN300-698228
    • SB83949
    • G72067
    • Tavaborole Impurity B; 5-Fluoro-2-hydroxybenzenemethanol; 5-Fluoro-2-hydroxybenzyl Alcohol; Benzenemethanol, 5-?fluoro-?2-?hydroxy-
    • IMEOTXXUGOGZCY-UHFFFAOYSA-N
    • CS-0378181
    • DTXSID10442331
    • 5-fluoro-2-hydroxybenzyl alcohol
    • BS-22092
    • 5-FLUORO-2-(HYDROXY)BENZYL ALCOHOL
    • 2357-33-7
    • MDL: MFCD03412237
    • Inchi: 1S/C7H7FO2/c8-6-1-2-7(10)5(3-6)4-9/h1-3,9-10H,4H2
    • InChI Key: IMEOTXXUGOGZCY-UHFFFAOYSA-N
    • SMILES: FC1C=CC(=C(C=1)CO)O

Computed Properties

  • Exact Mass: 142.04301
  • Monoisotopic Mass: 142.04300762g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 1
  • Complexity: 108
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.1
  • Topological Polar Surface Area: 40.5?2

Experimental Properties

  • PSA: 40.46
  • LogP: 1.02360

4-Fluoro-2-(hydroxymethyl)phenol Pricemore >>

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Additional information on 4-Fluoro-2-(hydroxymethyl)phenol

Fluorohydroxybenzylalcohol (CAS No. 2357-33-7): Properties, Applications, and Market Insights

Fluorohydroxybenzylalcohol (CAS No. 2357-33-7) is a specialized organic compound that has garnered significant attention in recent years due to its unique chemical properties and versatile applications. This aromatic alcohol, characterized by the presence of both fluorine and hydroxyl functional groups, serves as a valuable intermediate in pharmaceutical synthesis, material science, and specialty chemicals. The growing demand for fluorinated compounds in modern chemistry has positioned Fluorohydroxybenzylalcohol as a compound of interest for researchers and industrial applications alike.

The molecular structure of Fluorohydroxybenzylalcohol combines the reactivity of a benzyl alcohol with the electronic effects of fluorine substitution. This combination enhances its utility in nucleophilic substitution reactions and cross-coupling reactions, making it particularly valuable in the synthesis of complex organic molecules. Recent studies have highlighted its potential in developing bioactive molecules, with applications ranging from pharmaceutical intermediates to agrochemical formulations.

One of the most searched topics related to Fluorohydroxybenzylalcohol is its role in green chemistry and sustainable synthesis. As environmental regulations become stricter, researchers are exploring eco-friendly methods to produce and utilize this compound. Questions like "How is Fluorohydroxybenzylalcohol synthesized sustainably?" or "What are the biodegradable applications of fluorinated benzyl alcohols?" reflect current industry trends. The compound's potential in catalysis and renewable energy applications has also sparked interest among scientists.

In the pharmaceutical sector, Fluorohydroxybenzylalcohol serves as a key building block for drug discovery. Its fluorine moiety often improves the metabolic stability and bioavailability of potential drug candidates. Recent patents have disclosed its use in developing central nervous system (CNS) therapeutics and anti-inflammatory agents. The compound's ability to participate in click chemistry reactions makes it particularly valuable for combinatorial chemistry approaches.

The material science applications of Fluorohydroxybenzylalcohol are equally impressive. It has been investigated as a monomer for high-performance polymers with enhanced thermal stability and chemical resistance. Researchers are particularly interested in its potential for creating fluorinated coatings that exhibit superior water repellency and durability. These properties align well with the current market demand for advanced surface materials in various industries.

From a market perspective, the global demand for Fluorohydroxybenzylalcohol has shown steady growth, particularly in regions with strong pharmaceutical and specialty chemical industries. Analytical reports suggest increasing interest from Asia-Pacific markets, where the compound finds applications in electronic materials and fine chemicals. The compound's niche applications in liquid crystal displays and optical materials have further expanded its commercial potential.

Quality control and analytical methods for Fluorohydroxybenzylalcohol represent another area of frequent inquiry. Modern techniques such as HPLC analysis, mass spectrometry, and NMR spectroscopy are commonly employed to ensure the compound's purity and consistency. These analytical approaches are crucial for applications requiring high-purity intermediates, particularly in pharmaceutical manufacturing.

Storage and handling considerations for Fluorohydroxybenzylalcohol often appear in technical discussions. While the compound is generally stable under recommended conditions, proper chemical storage protocols should be followed to maintain its integrity. The compound's solubility characteristics in various organic solvents are also frequently researched, as this information is vital for formulation scientists and process chemists.

Looking to the future, research on Fluorohydroxybenzylalcohol continues to explore novel synthetic routes and applications. The compound's versatility makes it a subject of ongoing investigation in medicinal chemistry, materials science, and catalysis. As sustainable chemistry practices evolve, we can anticipate more environmentally benign processes for producing and utilizing this valuable fluorinated intermediate.

For researchers and industry professionals seeking detailed technical data on Fluorohydroxybenzylalcohol (CAS No. 2357-33-7), comprehensive resources are available through chemical databases and specialty chemical suppliers. The compound's unique combination of fluorine chemistry and alcohol functionality ensures its continued relevance in advanced chemical research and industrial applications across multiple sectors.

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