Cas no 235097-76-4 (2-Isopropoxyethyl Methanesulfonate)

2-Isopropoxyethyl Methanesulfonate is a methanesulfonate ester derivative characterized by its isopropoxyethyl functional group. This compound is commonly employed as an alkylating agent in organic synthesis, particularly in the preparation of modified nucleosides and other fine chemicals. Its reactive methanesulfonate group facilitates efficient nucleophilic substitution reactions, while the isopropoxyethyl moiety enhances solubility in organic solvents, improving reaction handling. The compound is valued for its stability under controlled conditions and its ability to introduce isopropoxyethyl groups into target molecules with high selectivity. Suitable for use in pharmaceutical intermediates and specialty chemical applications, it offers a balance of reactivity and manageable handling properties.
2-Isopropoxyethyl Methanesulfonate structure
235097-76-4 structure
Product Name:2-Isopropoxyethyl Methanesulfonate
CAS No:235097-76-4
MF:C6H14O4S
MW:182.237961292267
MDL:MFCD02093478
CID:245419
PubChem ID:18465045
Update Time:2025-10-28

2-Isopropoxyethyl Methanesulfonate Chemical and Physical Properties

Names and Identifiers

    • Ethanol,2-(1-methylethoxy)-, 1-methanesulfonate
    • 2-propan-2-yloxyethyl methanesulfonate
    • 2-Isopropoxyethyl Methanesulfonate
    • 2-isopropyloxyethyl mesylate
    • M1297
    • Methanesulfonic Acid 2-Isopropoxyethyl Ester
    • AKOS025294961
    • SCHEMBL506611
    • 2-(propan-2-yloxy)ethyl methanesulfonate
    • EN300-133454
    • CS-0154147
    • 2-[(Propan-2-yl)oxy]ethyl methanesulfonate
    • 2-(isopropoxy)ethyl mesylate
    • YDKQNGZSQDGFRB-UHFFFAOYSA-N
    • SY055358
    • MFCD02093478
    • 235097-76-4
    • DTXSID30594109
    • MethanesulfonicAcid2-IsopropoxyethylEster
    • D80698
    • Ethanol, 2-(1-methylethoxy)-, 1-methanesulfonate
    • 2-IsopropoxyethylMethanesulfonate>Ethanol, 2-(1-methylethoxy)-, 1-methanesulfonate
    • 2-propan-2-yloxyethylmethanesulfonate
    • DB-116844
    • MDL: MFCD02093478
    • Inchi: 1S/C6H14O4S/c1-6(2)9-4-5-10-11(3,7)8/h6H,4-5H2,1-3H3
    • InChI Key: YDKQNGZSQDGFRB-UHFFFAOYSA-N
    • SMILES: S(C)(=O)(=O)OCCOC(C)C

Computed Properties

  • Exact Mass: 182.06100
  • Monoisotopic Mass: 182.06128010g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 5
  • Complexity: 177
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: 0.3
  • Topological Polar Surface Area: 61?2

Experimental Properties

  • Color/Form: Not determined
  • Density: 1,14 g/cm3
  • Boiling Point: 279.7±23.0 °C at 760 mmHg
  • Flash Point: 122.9±22.6 °C
  • Refractive Index: 1.4300-1.4330
  • PSA: 60.98000
  • LogP: 1.46840
  • Solubility: Not determined
  • Vapor Pressure: 0.0±0.6 mmHg at 25°C

2-Isopropoxyethyl Methanesulfonate Security Information

2-Isopropoxyethyl Methanesulfonate Customs Data

  • HS CODE:2909499000
  • Customs Data:

    China Customs Code:

    2909499000

    Overview:

    2909499000 Other ether alcohols and their halogenation\sulfonation\Nitrosative or nitrosative derivatives. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:5.5% general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

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Additional information on 2-Isopropoxyethyl Methanesulfonate

Professional Introduction to Compound with CAS No. 235097-76-4 and Product Name: 2-Isopropoxyethyl Methanesulfonate

The compound with the CAS number 235097-76-4 and the product name 2-Isopropoxyethyl Methanesulfonate represents a significant advancement in the field of specialty chemicals, particularly in pharmaceutical and biochemical applications. This compound, characterized by its unique molecular structure, has garnered considerable attention due to its versatile reactivity and potential utility in various synthetic pathways. The 2-Isopropoxyethyl Methanesulfonate moiety, featuring a methanesulfonate ester group linked to an isopropoxyethyl chain, offers a balanced combination of solubility, stability, and reactivity, making it a valuable intermediate in organic synthesis.

In recent years, the demand for high-purity intermediates in drug development has surged, driven by the need for more efficient and selective synthetic methodologies. The 2-Isopropoxyethyl Methanesulfonate compound has emerged as a promising candidate in this context. Its structural features allow for facile functionalization at multiple sites, enabling chemists to design complex molecules with precision. This adaptability is particularly advantageous in the synthesis of active pharmaceutical ingredients (APIs), where structural diversity is often critical for achieving desired pharmacological properties.

One of the most compelling aspects of 2-Isopropoxyethyl Methanesulfonate is its role as a synthetic building block. The methanesulfonate ester group is known for its stability under a wide range of conditions, while the isopropoxyethyl chain provides a flexible handle for further chemical modifications. This dual functionality has been leveraged in the development of novel therapeutic agents targeting various diseases. For instance, researchers have utilized derivatives of this compound to synthesize inhibitors of key enzymes involved in metabolic disorders and inflammatory pathways.

Recent studies have highlighted the potential of 2-Isopropoxyethyl Methanesulfonate in the field of drug delivery systems. Its ability to form stable complexes with hydrophobic molecules has been exploited to enhance the bioavailability of poorly soluble drugs. By incorporating this compound into polymeric micelles or nanoparticles, researchers have been able to improve drug delivery efficiency, leading to more effective therapeutic outcomes. These advancements underscore the importance of 2-Isopropoxyethyl Methanesulfonate as a multifunctional tool in pharmaceutical research.

The compound’s utility extends beyond pharmaceutical applications into agrochemicals and material science. In agrochemicals, derivatives of 2-Isopropoxyethyl Methanesulfonate have been investigated as potential herbicides and fungicides due to their ability to interact with biological targets at low concentrations. Similarly, in material science, its incorporation into polymer matrices has been shown to enhance thermal stability and mechanical strength, opening up new possibilities for high-performance materials.

From a chemical synthesis perspective, 2-Isopropoxyethyl Methanesulfonate serves as an excellent precursor for introducing diverse functional groups into molecular frameworks. Its reactivity allows for transformations such as nucleophilic substitution, elimination reactions, and coupling reactions, all of which are essential for constructing complex organic molecules. The compound’s compatibility with various reaction conditions makes it a preferred choice for synthetic chemists working on intricate molecular architectures.

The industrial production of 2-Isopropoxyethyl Methanesulfonate has also seen significant advancements. Modern manufacturing processes focus on optimizing yield and purity while minimizing environmental impact. Continuous flow chemistry techniques have been particularly effective in producing this compound efficiently and sustainably. These innovations ensure that researchers and manufacturers have access to high-quality starting materials without compromising on ecological considerations.

Future research directions for 2-Isopropoxyethyl Methanesulfonate are likely to focus on expanding its applications into emerging fields such as biotechnology and nanomedicine. The compound’s unique properties make it well-suited for developing novel biomaterials and diagnostic tools. For example, its ability to form stable conjugates with biomolecules could be harnessed in the creation of targeted therapeutics or biosensors capable of detecting specific biological markers.

In conclusion, the compound with CAS number 235097-76-4, known as 2-Isopropoxyethyl Methanesulfonate, represents a cornerstone in modern chemical synthesis and pharmaceutical development. Its versatility, reactivity, and adaptability make it an indispensable tool for researchers across multiple disciplines. As scientific understanding continues to evolve, it is anticipated that this compound will play an even greater role in shaping the future of medicine and material science.

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