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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Aniline and substituted anilines Sulfonylanilines
• Solvents and Organic Chemicals Organic Compounds Amines/Sulfonamides
• Solvents and Organic Chemicals Organic Compounds

Comprehensive Overview of 3-Chloro-4-methylsulfonylaniline (CAS No. 23153-12-0): Properties, Applications, and Industry Insights

3-Chloro-4-methylsulfonylaniline (CAS No. 23153-12-0) is a specialized organic compound widely recognized for its role in pharmaceutical and agrochemical synthesis. This sulfonylaniline derivative features a unique molecular structure combining a chloro substituent and a methylsulfonyl group, making it a valuable intermediate in modern chemical research. With the growing demand for high-purity chemical intermediates, this compound has garnered significant attention in both academic and industrial circles.

The compound’s chemical stability and reactivity are key factors driving its adoption. Researchers highlight its utility in cross-coupling reactions, particularly in the development of bioactive molecules. Recent studies emphasize its compatibility with palladium-catalyzed processes, a trending topic in green chemistry forums. As industries shift toward sustainable synthesis methods, 3-Chloro-4-methylsulfonylaniline is increasingly explored for its potential in low-waste production pathways.

From an analytical perspective, advanced techniques like HPLC and LC-MS are employed to verify the purity of CAS No. 23153-12-0. Quality control protocols often reference ICH guidelines, aligning with global regulatory standards—a frequent search query among quality assurance professionals. The compound’s spectral data (IR, NMR) is meticulously documented in peer-reviewed journals, addressing another common information need in synthetic chemistry communities.

Market trends reveal rising interest in custom synthesis services for this aniline derivative, particularly from contract research organizations (CROs). This aligns with the broader industry movement toward specialty chemicals outsourcing. Furthermore, its applications in electronic materials—such as organic semiconductors—have sparked discussions in materials science forums, correlating with increased searches for "sulfonyl-containing electronic additives."

Environmental considerations are also shaping the narrative around 3-Chloro-4-methylsulfonylaniline. Recent publications examine its biodegradation pathways, responding to growing concerns about persistent organic pollutants. This positions the compound within the larger conversation about green chemistry metrics—a hot topic in 2024’s research landscape. Computational chemistry studies modeling its molecular interactions further enhance understanding of its environmental footprint.

In supply chain contexts, manufacturers emphasize GMP-compliant production of CAS No. 23153-12-0 to meet pharmaceutical-grade requirements. This addresses frequent queries about "pharma intermediate suppliers" in search engines. Storage recommendations typically highlight protection from oxidative degradation, with technical datasheets often citing nitrogen blanket storage best practices—a detail highly valued by industrial purchasers.

The compound’s role in heterocyclic chemistry continues to expand, particularly in constructing benzothiazole scaffolds. This application resonates with researchers investigating fluorescence markers, a subject gaining traction in diagnostic imaging studies. Patent analyses show a steady increase in filings involving 3-Chloro-4-methylsulfonylaniline-based innovations, particularly in photodynamic therapy applications.

From a regulatory standpoint, REACH compliance documentation for this material remains a frequently updated resource, matching the needs of EU-based chemical distributors. Safety assessments often reference OECD test guidelines, another high-search-volume term among regulatory affairs specialists. These aspects make comprehensive technical dossiers essential for commercial distribution.

Emerging applications in crop protection formulations demonstrate the compound’s versatility beyond pharmaceuticals. Agrochemical researchers are investigating its potential as a synergistic additive in herbicide systems, coinciding with increased searches for "sulfonamide-based agrochemicals." This dual-use profile significantly enhances its market potential across multiple industries.

In conclusion, 3-Chloro-4-methylsulfonylaniline (CAS No. 23153-12-0) represents a multifaceted chemical building block with expanding relevance across scientific disciplines. Its evolving applications—from medicinal chemistry to advanced materials—reflect broader trends in functionalized aniline utilization. As research continues to uncover new possibilities, this compound remains at the forefront of specialty intermediate innovation.

• 23929-35-3(3-(4-Chlorophenyl)sulfonylbenzenamine)
• 35880-73-0(Benzenamine, 4,4'-sulfonylbis[3-chloro-)
• 66816-47-5(BENZENAMINE, 2,5-DICHLORO-3-(METHYLSULFONYL)-)
• 62605-99-6(Benzenamine, 3-chloro-5-(methylsulfonyl)-)
• 61174-37-6(Benzenamine, 2-[(2,6-dichlorophenyl)sulfonyl]-)
• 90309-23-2(BENZENAMINE, 4-[(2,4,5-TRICHLOROPHENYL)SULFONYL]-)
• 105456-57-3(Benzenamine, 4-[(2,4-dichlorophenyl)sulfonyl]-)
• 105456-63-1(Benzenamine, 4-[(2,4,6-trichlorophenyl)sulfonyl]-)
• 141211-87-2(Benzenamine, 4-chloro-3-[(4-chlorophenyl)sulfonyl]-)
• 7146-68-1(4-Amino-4'-chlorodiphenyl Sulfone)