Cas no 23062-24-0 (Eurycomalactone)

Eurycomalactone is a bioactive quassinoid compound primarily isolated from Eurycoma longifolia (Tongkat Ali). It exhibits notable pharmacological properties, including anti-inflammatory, antiproliferative, and antimalarial activities. Structurally characterized by a lactone moiety, eurycomalactone demonstrates selective cytotoxicity against certain cancer cell lines, making it a subject of interest in oncology research. Its mechanism of action involves modulation of cellular signaling pathways, such as NF-κB inhibition. The compound also shows potential in enhancing male fertility by influencing testosterone synthesis. Due to its high purity and standardized extraction methods, eurycomalactone is valued for preclinical and biochemical studies. Stability and solubility profiles are optimized for research applications.
Eurycomalactone structure
Eurycomalactone structure
Product Name:Eurycomalactone
CAS No:23062-24-0
MF:C19H24O6
MW:348.390266418457
CID:257177
PubChem ID:441793
Update Time:2025-05-28

Eurycomalactone Chemical and Physical Properties

Names and Identifiers

    • 2,5-Methanonaphth[1,2-d]oxepin-4,6,10(2H)-trione,1,5,5a,7,7a,11,11a,11b-octahydro-1,11-dihydroxy-5a,8,11a,12-tetramethyl-,(1R,2R,5S,5aR,7aS,11S,11aS,11bR,12R)-
    • 2,5-Methanonaphth[1,2-d]oxepin-4,6,10(2H)-trione,1,5,5a,7,7a,11,11a,11b-octahydro-1,11-dihydroxy-5a,8,11a,12-tetramethyl-,(1R
    • Eurycomalactone
    • EURYCOMALACTONE(AS)
    • EURYCOMALACTONE(SH)
    • 1H-Phenanthro(10,1-bc)furan-4,6,9(2H,5aH,6aH)-trione, 3,3a,10,10a,10b,10c-hexahydro-2,10-dihydroxy-3,7,10a,10c-tetramethyl-
    • AC1L9BO4
    • C08759
    • CHEMBL1081239
    • (1R,2R,5S,5aR,7aS,11S,11aS,11bR,12R)-1,5,5a,7,7a,11,11a,11b-Octahydro-1,11-dihydroxy-5a,8,11a,12-tetramethyl-2,5-methanonaphth[1,2-d]oxepin-4,6,10(2H)-trione
    • (1S,2R,9S,10S,12R,13R,16R)-9,12-Dihydroxy-2,6,10,16-tetramethyl-14-oxatetracyclo[11.2.1.02,11.05,10]
    • 9,12-Dihydroxy-2,6,10,16-tetramethyl-14-oxatetracyclo[11.2.1.02,11.05,10]hexadec-6-ene-3,8,15-trione
    • (1S,2R,5S,9S,10S,11R,12R,13R,16R)-9,12-dihydroxy-2,6,10,16-tetramethyl-14-oxatetracyclo[11.2.1.02,11.05,10]hexadec-6-ene-3,8,15-trione
    • DTXSID20177627
    • MS-25365
    • CHEBI:4944
    • AKOS040760395
    • EURYCOMALACTONE(P)
    • 23062-24-0
    • Q27106580
    • (1S,2R,5S,9S,10S,11R,12R,13R,16R)-9,12-dihydroxy-2,6,10,16-tetramethyl-14-oxatetracyclo(11.2.1.02,11.05,10)hexadec-6-ene-3,8,15-trione
    • DTXCID80100118
    • G16955
    • MDL: MFCD09264652
    • Inchi: 1S/C19H24O6/c1-7-5-10(20)16(23)18(3)9(7)6-11(21)19(4)12-8(2)14(25-17(12)24)13(22)15(18)19/h5,8-9,12-16,22-23H,6H2,1-4H3/t8-,9+,12-,13+,14-,15-,16-,18+,19+/m1/s1
    • InChI Key: OGHYZHNTIINXEO-MGBQOKOWSA-N
    • SMILES: O1C([C@H]2[C@@H](C)[C@@H]1[C@@H]([C@@H]1[C@@]3(C)[C@@H](C(C=C(C)[C@@H]3CC([C@]12C)=O)=O)O)O)=O

Computed Properties

  • Exact Mass: 348.15700
  • Monoisotopic Mass: 348.157289
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 6
  • Heavy Atom Count: 25
  • Rotatable Bond Count: 0
  • Complexity: 725
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 9
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 0.1
  • Topological Polar Surface Area: 101
  • Molecular Weight: 348.4

Experimental Properties

  • Color/Form: Cryst.
  • Density: 1.328±0.06 g/cm3 (20 oC 760 Torr),
  • Melting Point: 268-270 oC
  • Boiling Point: 588.1°C at 760 mmHg
  • Flash Point: 213.1°C
  • Refractive Index: 1.575
  • Solubility: Slightly soluble (1 g/l) (25 o C),
  • PSA: 100.90000
  • LogP: 0.64630
  • Vapor Pressure: 0.0±3.7 mmHg at 25°C

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(CAS:23062-24-0)Eurycomalactone
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Purity:≥98%
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