Cas no 2304635-53-6 (Tert-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)azetidine-1-carboxylate)

Tert-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)azetidine-1-carboxylate is a boronic ester derivative featuring an azetidine core protected by a Boc (tert-butoxycarbonyl) group. This compound serves as a versatile intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the synthesis of complex organic molecules, particularly in pharmaceutical and agrochemical research. The presence of the Boc group enhances stability and facilitates selective deprotection under mild conditions. Its tetramethyl-1,3,2-dioxaborolane moiety ensures improved solubility and handling compared to free boronic acids. This reagent is particularly valuable for constructing nitrogen-containing heterocycles, offering efficient functionalization in medicinal chemistry applications.
Tert-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)azetidine-1-carboxylate structure
2304635-53-6 structure
Product Name:Tert-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)azetidine-1-carboxylate
CAS No:2304635-53-6
MF:C14H26BNO4
MW:283.171544551849
MDL:MFCD29764413
CID:4711589
PubChem ID:118992045
Update Time:2025-11-01

Tert-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)azetidine-1-carboxylate Chemical and Physical Properties

Names and Identifiers

    • tert-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)azetidine-1-carboxylate
    • 1-Boc-Azetidine-3-boronic acid pinacol ester
    • 1-Boc-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)azetidine
    • t-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)azetidine-1-carboxylate
    • 3-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-azetidine-1-carboxylic acid tert-butyl ester
    • CS-0176781
    • DB-160160
    • tert-Butyl3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)azetidine-1-carboxylate
    • tert-butyl 3-(tetramethyl-1,3,2-dioxaborolan-2-yl)azetidine-1-carboxylate
    • P18778
    • Z1965996257
    • XH0433
    • 1-Azetidinecarboxylic acid, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, 1,1-dimethylethyl ester
    • SB52161
    • SY270340
    • EN300-197338
    • 2304635-53-6
    • MFCD29764413
    • Tert-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)azetidine-1-carboxylate
    • MDL： MFCD29764413
    • Inchi： 1S/C14H26BNO4/c1-12(2,3)18-11(17)16-8-10(9-16)15-19-13(4,5)14(6,7)20-15/h10H,8-9H2,1-7H3
    • InChI Key： OGIREDKIFYTFOQ-UHFFFAOYSA-N
    • SMILES： O1B(C2CN(C(=O)OC(C)(C)C)C2)OC(C)(C)C1(C)C

Computed Properties

  • Exact Mass: 283.1954885 g/mol
  • Monoisotopic Mass: 283.1954885 g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 20
  • Rotatable Bond Count: 3
  • Complexity: 381
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Molecular Weight: 283.17
  • Topological Polar Surface Area: 48

Experimental Properties

  • Density: 1.05±0.1 g/cm3(Predicted)
  • Boiling Point: 323.8±35.0 °C(Predicted)
  • pka: -0.93±0.40(Predicted)

Tert-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)azetidine-1-carboxylate Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Chemenu
CM328646-5g
tert-butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)azetidine-1-carboxylate
 2304635-53-6 95%+
5g
 $4048 2021-06-16
Chemenu
CM328646-1g
tert-butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)azetidine-1-carboxylate
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abcr
AB544031-250 mg
1-Boc-azetidine-3-boronic acid pinacol ester, 95%; .
 2304635-53-6 95%
250MG
 €376.90 2023-07-11
abcr
AB544031-1 g
1-Boc-azetidine-3-boronic acid pinacol ester, 95%; .
 2304635-53-6 95%
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 €907.30 2023-07-11
SHANG HAI BI DE YI YAO KE JI GU FEN Co., Ltd.
BD457595-1g
tert-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)azetidine-1-carboxylate
 2304635-53-6 97%
1g
 ￥5193.0 2022-03-01
eNovation Chemicals LLC
D587591-100mg
tert-butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)azetidine-1-carboxylate
 2304635-53-6 97%
100mg
 $115 2024-07-21
eNovation Chemicals LLC
D587591-250MG
tert-butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)azetidine-1-carboxylate
 2304635-53-6 97%
250mg
 $145 2024-07-21
eNovation Chemicals LLC
D587591-500MG
tert-butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)azetidine-1-carboxylate
 2304635-53-6 97%
500mg
 $225 2024-07-21
eNovation Chemicals LLC
D587591-1G
tert-butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)azetidine-1-carboxylate
 2304635-53-6 97%
1g
 $320 2024-07-21
eNovation Chemicals LLC
D587591-5G
tert-butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)azetidine-1-carboxylate
 2304635-53-6 97%
5g
 $1100 2024-07-21

Tert-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)azetidine-1-carboxylate Related Literature

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