• 1. Elusive 2-aminofuran Diels–Alder substrates for a straightforward synthesis of polysubstituted anilines?
  Ana G. Neo,Ana Bornadiego,Jesús Díaz,Stefano Marcaccini,Carlos F. Marcos Org. Biomol. Chem., 2013,11, 6546-6555
• 2. Evidence of rutile-to-anatase photo-induced electron transfer in mixed-phase TiO2 by solid-state NMR spectroscopy?
  Weili Dai,Guangjun Wu,Michael Hunger Chem. Commun., 2015,51, 13779-13782
• 3. Fast-Track to Research Data Management in Experimental Material Science-Setting the Ground for Research Group Level Materials Digitalization.
  LarsBanko,AlfredLudwig
• 4. Fe3O4 nanoclusters highly dispersed on a porous graphene support as an additive for improving the hydrogen storage properties of LiBH4?
  Guang Xu,Wei Zhang,Ying Zhang,Xiaoxia Zhao,Ping Wen,Di Ma RSC Adv., 2018,8, 19353-19361
• 5. Evolution of dealloying induced strain in nanoporous gold crystals?
  Ross Harder,David C. Dunand,Ian McNulty Nanoscale, 2017,9, 5686-5693

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Quinolines and derivatives Haloquinolines

8-Bromo-6-fluoroquinoline: A Comprehensive Overview

8-Bromo-6-fluoroquinoline, also known by its CAS registry number CAS No. 22960-18-5, is a heterocyclic aromatic compound that has garnered significant attention in the fields of organic chemistry, pharmacology, and materials science. This compound is characterized by its quinoline skeleton, which is a bicyclic structure consisting of a benzene ring fused to a pyridine ring. The substitution pattern of this molecule, with a bromine atom at position 8 and a fluorine atom at position 6, imparts unique electronic and steric properties that make it valuable for various applications.

The synthesis of 8-Bromo-6-fluoroquinoline typically involves multi-step processes that require precise control over reaction conditions to achieve the desired substitution pattern. Recent advancements in synthetic methodologies have enabled the efficient preparation of this compound using techniques such as nucleophilic aromatic substitution and transition-metal-catalyzed coupling reactions. These methods not only improve the yield but also enhance the purity of the final product, which is critical for its use in research and industrial applications.

One of the most promising areas of research involving 8-Bromo-6-fluoroquinoline is its application in drug discovery. The quinoline framework is well-known for its pharmacological activity, and the introduction of bromine and fluorine substituents further modulates the compound's bioactivity. Studies have shown that this compound exhibits potential anti-inflammatory, antitumor, and antimicrobial properties. For instance, recent research has demonstrated that 8-Bromo-6-fluoroquinoline can inhibit the activity of certain enzymes associated with inflammation, making it a candidate for developing novel therapeutic agents.

In addition to its biological applications, 8-Bromo-6-fluoroquinoline has also found utility in materials science. Its aromaticity and electron-withdrawing substituents make it suitable for use in organic electronics. Researchers have explored its potential as a building block for constructing advanced materials such as organic semiconductors and light-emitting diodes (LEDs). The compound's ability to form stable charge transfer complexes with other organic molecules further enhances its applicability in this field.

The physical and chemical properties of 8-Bromo-6-fluoroquinoline are well-documented, which facilitates its characterization and application. For example, its melting point, solubility, and UV-vis absorption spectra have been extensively studied to understand its behavior under various conditions. These studies are essential for optimizing its use in both laboratory settings and industrial processes.

In conclusion, 8-Bromo-6-fluoroquinoline, with its unique structural features and versatile properties, continues to be a subject of intense research across multiple disciplines. As new applications emerge and synthetic methods improve, this compound is poised to play an increasingly important role in advancing scientific knowledge and technological innovations.

• 292636-09-0(7-Bromo-4-fluoro-1H-indole)
• 225366-90-5(3-bromo-7-fluoroquinoline)
• 917251-99-1(8-Bromo-5-fluoroquinoline)
• 408355-23-7(7-Bromo-5-fluoro-1H-indole)
• 1000339-62-7(7-bromo-6-fluoro-1H-Indole)
• 29263-09-0(7-bromo-4-fluoroindole)
• 205114-16-5(3-bromo-6-fluoroquinoline)
• 877160-16-2(7-bromo-4,5-difluoro-1H-indole)
• 834884-06-9(8-bromo-3-fluoro-quinoline)
• 1416439-00-3(3-bromo-5-fluoro-quinoline)