Cas no 22812-50-6 (alpha-Naphthoflavanol)
alpha-Naphthoflavanol Chemical and Physical Properties
Names and Identifiers
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- 4H-Naphtho[1,2-b]pyran-4-one,3-hydroxy-2-phenyl-
- 7,8-Benzoflavone,3-hydroxy- (6CI)
- 3-hydroxy-2-phenyl-4H-benzo[h]chromen-4-one
- A-NAPHTHOFLAVONOL
- 22812-50-6
- 3-HYDROXY-2-PHENYLBENZO[H]CHROMEN-4-ONE
- BDBM50439840
- FT-0702903
- 3-hydroxy-alpha-naphthoflavone
- SCHEMBL17292888
- CHEMBL2420085
- alpha-Naphthoflavanol
-
- Inchi： 1S/C19H12O3/c20-16-15-11-10-12-6-4-5-9-14(12)19(15)22-18(17(16)21)13-7-2-1-3-8-13/h1-11,21H
- InChI Key： NXKPKOFDBHWAGX-UHFFFAOYSA-N
- SMILES： O1C(C2C=CC=CC=2)=C(C(C2=CC=C3C=CC=CC3=C12)=O)O
Computed Properties
- Exact Mass: 288.078644241g/mol
- Monoisotopic Mass: 288.078644241g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 22
- Rotatable Bond Count: 1
- Complexity: 475
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 4.3
- Topological Polar Surface Area: 46.5?2
alpha-Naphthoflavanol Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | A213760-250mg |
alpha-Naphthoflavanol |
22812-50-6 | 250mg |
$ 200.00 | 2022-06-08 | ||
| TRC | A213760-500mg |
alpha-Naphthoflavanol |
22812-50-6 | 500mg |
$ 325.00 | 2022-06-08 | ||
| TRC | A213760-1000mg |
alpha-Naphthoflavanol |
22812-50-6 | 1g |
$ 515.00 | 2022-06-08 |
alpha-Naphthoflavanol Related Literature
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Xianghong Wang,Xin Chen,Lingjie Song,Rongtao Zhou,Shifang Luan J. Mater. Chem. B 2020 8 9325
Additional information on alpha-Naphthoflavanol
Comprehensive Guide to alpha-Naphthoflavanol (CAS No. 22812-50-6): Properties, Applications, and Research Insights
alpha-Naphthoflavanol (CAS No. 22812-50-6) is a bioactive flavonoid derivative that has garnered significant attention in pharmaceutical and biochemical research. This compound, structurally related to flavanols, exhibits unique properties that make it a subject of interest in studies focusing on antioxidant activity, enzyme modulation, and cellular signaling pathways. Its molecular framework combines a naphthalene ring with a flavanol backbone, offering distinct chemical reactivity and biological interactions.
Recent trends in scientific literature highlight the growing demand for natural and synthetic flavonoids like alpha-Naphthoflavanol due to their potential in nutraceutical formulations and disease prevention. Researchers are particularly intrigued by its role in modulating cytochrome P450 enzymes, a hot topic in drug metabolism studies. This aligns with frequent search queries such as "flavonoids for liver health" or "natural enzyme inhibitors," reflecting public interest in bioactive compounds.
The physicochemical profile of 22812-50-6 reveals a melting point range of 160-165°C and moderate solubility in organic solvents, which is critical for its extraction methods and purification processes. Analytical techniques like HPLC and mass spectrometry are commonly employed for its characterization, addressing another common search term: "how to identify flavonoid compounds." These properties make it valuable for quality control in supplement manufacturing.
In pharmacological contexts, alpha-Naphthoflavanol has shown promise in preliminary studies for its anti-inflammatory effects, with mechanisms potentially involving NF-kB pathway inhibition. This connects to trending health topics like "natural alternatives to NSAIDs." However, researchers emphasize the need for more clinical trials to validate these effects, a point often raised in academic discussions about flavonoid therapeutics.
The compound's structure-activity relationship (SAR) has become a focal point for medicinal chemistry optimization. Computational modeling searches for "flavonoid docking studies" frequently include this molecule due to its balanced hydrophobicity and hydrogen-bonding capacity. Such features make it a valuable lead compound for designing novel therapeutic agents targeting oxidative stress-related conditions.
Industrial applications of 22812-50-6 extend to cosmeceutical products, where its potential anti-aging properties are being explored. This aligns with booming market searches for "plant-derived active ingredients in skincare." Formulators value its stability in emulsions and compatibility with common delivery systems like liposomes, addressing another frequent query about "flavonoid bioavailability enhancement."
Environmental researchers have investigated alpha-Naphthoflavanol's role in plant defense mechanisms, connecting to popular ecological topics like "natural pesticide alternatives." Its occurrence in certain botanicals and biosynthetic pathways also makes it relevant to discussions about sustainable sourcing of bioactive compounds, a growing concern among conscious consumers.
From a regulatory perspective, alpha-Naphthoflavanol falls under generally recognized as safe (GRAS) status for research purposes, though specific applications may require additional safety assessments. This addresses common regulatory questions about flavonoid-containing products. Standardization methods using chromatographic fingerprints ensure batch-to-batch consistency, crucial for reproducible research outcomes.
Future research directions for CAS No. 22812-50-6 include exploring its synergistic effects with other phytochemicals—a trending topic in functional food development. Advanced formulation technologies like nanoencapsulation may overcome its moderate water solubility, answering frequent formulation challenges searched by industrial chemists. These developments position alpha-Naphthoflavanol as a compound with expanding commercial and scientific relevance.
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