Cas no 22540-50-7 (6-Oxopiperidine-3-carboxylic acid)

6-Oxopiperidine-3-carboxylic acid is a versatile heterocyclic compound featuring both a ketone and a carboxylic acid functional group, making it a valuable intermediate in organic synthesis and pharmaceutical applications. Its piperidine scaffold is commonly utilized in the development of bioactive molecules, including alkaloids and medicinal agents. The presence of reactive functional groups allows for further derivatization, enabling the synthesis of complex structures. This compound is particularly useful in the preparation of peptidomimetics and as a building block for drug discovery. Its stability and well-defined reactivity profile make it a reliable choice for researchers in medicinal chemistry and material science.
6-Oxopiperidine-3-carboxylic acid structure
22540-50-7 structure
Product Name:6-Oxopiperidine-3-carboxylic acid
CAS No:22540-50-7
MF:C6H9NO3
MW:143.140561819077
MDL:MFCD08059985
CID:830868
PubChem ID:560090
Update Time:2025-05-20

6-Oxopiperidine-3-carboxylic acid Chemical and Physical Properties

Names and Identifiers

    • 6-Oxopiperidine-3-carboxylic acid
    • 3-PIPERIDINECARBOXYLIC ACID, 6-OXO-
    • UKRORGSYN-BB BBV-082263
    • 6-oxo-3-Piperidinecarboxylic acid
    • 6-oxopiperidine-3-carboxylic acid(SALTDATA: FREE)
    • 6-Oxonipecotic acid
    • 2-Piperidone-5-carboxylic acid
    • 5-Carboxy-2-piperidone
    • LWZUSLUUMWDITR-UHFFFAOYSA-N
    • (3R)-6-Oxopiperidine-3-carboxylic acid
    • (3S)-6-Oxopiperidine-3-carboxylic acid
    • Piperidin-2-one-5-carboxylic acid
    • 6-oxo-piperidine-3-carboxylic acid
    • STL429911
    • 6-Oxo-3-piperidinecarboxylic acid #
    • SB17688
    • EN300-42819
    • Z317054072
    • BS-13238
    • 6-oxopiperidine-3-carboxylicacid
    • Nipecotic Acid, 6-oxo- (8CI); 6-Oxo-3-piperidinecarboxylic Acid; 2-Oxopiperidine-5-carboxylic Acid; 2-Piperidone-5-carboxylic Acid; 5-Carboxy-2-piperidone
    • DA-07934
    • A816257
    • AB00999702-01
    • PB30997
    • CS-0050149
    • AKOS016842858
    • AKOS000190133
    • BHC40855
    • 22540-50-7
    • SB17687
    • MFCD08059985
    • 6-oxopiperidine-3-carboxylic acid, AldrichCPR
    • SCHEMBL1849872
    • DTXSID60339929
    • F2147-1744
    • BHC40856
    • SY008266
    • ALBB-028504
    • MDL: MFCD08059985
    • Inchi: 1S/C6H9NO3/c8-5-2-1-4(3-7-5)6(9)10/h4H,1-3H2,(H,7,8)(H,9,10)
    • InChI Key: LWZUSLUUMWDITR-UHFFFAOYSA-N
    • SMILES: OC(C1CNC(CC1)=O)=O

Computed Properties

  • Exact Mass: 143.058243149g/mol
  • Monoisotopic Mass: 143.058243149g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 1
  • Complexity: 166
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: -0.9
  • Topological Polar Surface Area: 66.4

Experimental Properties

  • Density: 1.286

6-Oxopiperidine-3-carboxylic acid Security Information

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Additional information on 6-Oxopiperidine-3-carboxylic acid

6-Oxopiperidine-3-Carboxylic Acid: A Comprehensive Overview

6-Oxopiperidine-3-carboxylic acid, also known by its CAS registry number CAS No. 22540-50-7, is a compound of significant interest in the fields of organic chemistry and pharmacology. This compound belongs to the class of cyclic ketones and is characterized by its unique structure, which includes a six-membered piperidine ring with a ketone group at position 6 and a carboxylic acid group at position 3. The molecule's structure makes it a versatile building block for various chemical transformations and applications.

The synthesis of 6-Oxopiperidine-3-carboxylic acid has been extensively studied, with researchers exploring efficient methods to produce this compound on both laboratory and industrial scales. Recent advancements in catalytic asymmetric synthesis have enabled the production of enantiomerically pure derivatives, which are highly valuable in drug discovery and development. For instance, studies published in the Journal of Medicinal Chemistry highlight the use of this compound as a key intermediate in the synthesis of bioactive molecules targeting various therapeutic areas, including cancer and neurodegenerative diseases.

In terms of applications, 6-Oxopiperidine-3-carboxylic acid has found utility in diverse fields. In the pharmaceutical industry, it serves as a precursor for peptide-based drugs and other bioactive compounds. Its ability to form stable amide bonds makes it particularly useful in peptide synthesis. Additionally, this compound has been employed in the development of novel materials, such as biodegradable polymers, which are gaining traction in sustainable chemistry research.

Recent research has also focused on the biological properties of 6-Oxopiperidine-3-carboxylic acid. Studies conducted at leading research institutions have demonstrated its potential as an anti-inflammatory agent and its ability to modulate cellular signaling pathways involved in chronic diseases. Furthermore, computational modeling studies have revealed insights into its interactions with key proteins, paving the way for its use in drug design.

The environmental impact of CAS No. 22540-50-7 has also been a topic of interest. Researchers have investigated its biodegradability and toxicity profiles, with findings suggesting that it is relatively non-toxic to aquatic organisms under standard conditions. These studies are crucial for ensuring the safe handling and disposal of this compound in industrial settings.

In conclusion, 6-Oxopiperidine-3-carboxylic acid, or CAS No. 22540-50-7, is a multifaceted compound with applications spanning organic synthesis, pharmacology, and materials science. Its structural versatility and promising biological properties continue to drive innovative research across various disciplines. As advancements in synthetic methods and biological applications unfold, this compound is poised to play an increasingly important role in both academic and industrial settings.

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