Cas no 22483-40-5 (1-(2-Methoxyethoxy)-4-nitrobenzene)

1-(2-Methoxyethoxy)-4-nitrobenzene is a nitroaromatic compound featuring a methoxyethoxy substituent at the para position relative to the nitro group. This structural configuration imparts unique solubility and reactivity characteristics, making it a valuable intermediate in organic synthesis, particularly for the preparation of fine chemicals and pharmaceuticals. The ether linkage enhances its compatibility with polar solvents, while the nitro group offers versatile functionalization potential through reduction or nucleophilic substitution. Its well-defined chemical properties ensure consistent performance in applications such as dye synthesis, agrochemical development, and polymer modification. The compound is typically supplied in high purity, ensuring reliability in research and industrial processes.
1-(2-Methoxyethoxy)-4-nitrobenzene structure
22483-40-5 structure
Product Name:1-(2-Methoxyethoxy)-4-nitrobenzene
CAS No:22483-40-5
MF:C9H11NO4
MW:197.187942743301
MDL:MFCD00463497
CID:52081
PubChem ID:547809
Update Time:2025-05-23

1-(2-Methoxyethoxy)-4-nitrobenzene Chemical and Physical Properties

Names and Identifiers

    • 1-(2-Methoxyethoxy)-4-nitrobenzene
    • BENZENE, 1-(2-METHOXYETHOXY)-4-NITRO-
    • 4-Methoxyaethoxy-nitrobenzol
    • 4-Nitrophenyl-2-methoxyethyl ether
    • AMSIAIRQIAPAPM-UHFFFAOYSA-N
    • 4-Nitrophenyl 2-methoxyethyl ether
    • 4-(2-Methoxyethoxy)-1-nitrobenzene
    • 1-(2-Methoxyethoxy)-4-nitrobenzene #
    • AK113711
    • ST2414962
    • AB0059999
    • Z4445
    • 483N405
    • DS-0966
    • CS-0186226
    • MFCD00463497
    • SCHEMBL116052
    • 22483-40-5
    • AKOS006241293
    • A878529
    • FT-0763053
    • DTXSID60338235
    • 4-NITROPHENYL-2-METHOXYETHYLETHER
    • DA-07943
    • MDL: MFCD00463497
    • Inchi: 1S/C9H11NO4/c1-13-6-7-14-9-4-2-8(3-5-9)10(11)12/h2-5H,6-7H2,1H3
    • InChI Key: AMSIAIRQIAPAPM-UHFFFAOYSA-N
    • SMILES: O(C1C=CC(=CC=1)[N+](=O)[O-])CCOC

Computed Properties

  • Exact Mass: 197.06900
  • Monoisotopic Mass: 197.06880783g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 14
  • Rotatable Bond Count: 4
  • Complexity: 172
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2
  • Topological Polar Surface Area: 64.3

Experimental Properties

  • Melting Point: 88-91°C
  • Boiling Point: 503.8°C at 760 mmHg
  • PSA: 64.28000
  • LogP: 2.14320

1-(2-Methoxyethoxy)-4-nitrobenzene Security Information

1-(2-Methoxyethoxy)-4-nitrobenzene Customs Data

  • HS CODE:2909309090
  • Customs Data:

    China Customs Code:

    2909309090

    Overview:

    2909309090 Other aromatic ethers and their halogenated derivatives\sulfonation\Nitrated derivative(Including nitrosative derivatives).Regulatory conditions:nothing.VAT:17.0%.Tax refund rate:9.0%.MFN tariff:5.5%.general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

1-(2-Methoxyethoxy)-4-nitrobenzene Pricemore >>

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1-(2-Methoxyethoxy)-4-nitrobenzene Production Method

Additional information on 1-(2-Methoxyethoxy)-4-nitrobenzene

Comprehensive Overview of 1-(2-Methoxyethoxy)-4-nitrobenzene (CAS No. 22483-40-5): Properties, Applications, and Industry Insights

1-(2-Methoxyethoxy)-4-nitrobenzene (CAS No. 22483-40-5), also known by its systematic name, is a specialized organic compound that has garnered attention in pharmaceutical intermediates, agrochemical synthesis, and material science. This nitro-aromatic derivative features a methoxyethoxy functional group, which enhances its solubility and reactivity in various industrial processes. Researchers and manufacturers frequently search for "1-(2-Methoxyethoxy)-4-nitrobenzene suppliers" or "CAS 22483-40-5 applications," reflecting its niche yet critical role in fine chemical production.

The compound's molecular structure combines a benzene ring substituted with a nitro group (-NO2) and a 2-methoxyethoxy side chain (-OCH2CH2OCH3). This unique arrangement contributes to its versatility as a building block in organic synthesis. Recent trends in "green chemistry" and "sustainable synthesis" have spurred interest in optimizing its production methods to reduce environmental impact, aligning with global regulatory standards like REACH and FDA guidelines.

In the pharmaceutical sector, 1-(2-Methoxyethoxy)-4-nitrobenzene serves as a precursor for active pharmaceutical ingredients (APIs). Its nitrobenzene core is pivotal in constructing complex molecules, particularly in antiviral and antibacterial drug development. Searches for "nitrobenzene derivatives in medicine" often highlight its relevance. Additionally, its role in dye intermediates and liquid crystal materials makes it valuable in electronics and optoelectronics industries, where "high-purity nitrobenzene compounds" are in demand.

From a technical perspective, the compound exhibits moderate polarity due to its ether and nitro functionalities, making it soluble in common organic solvents like ethanol, acetone, and dimethyl sulfoxide (DMSO). Analytical techniques such as HPLC, GC-MS, and NMR are typically employed for quality control, addressing queries like "CAS 22483-40-5 analysis methods." Storage recommendations emphasize protection from light and moisture to maintain stability, a detail frequently sought by logistics professionals.

Emerging applications in "advanced material science" have further expanded its utility. For instance, researchers explore its incorporation into polymer matrices to modify thermal and optical properties. The compound's compatibility with cross-coupling reactions (e.g., Suzuki-Miyaura) also positions it as a candidate for designing novel organic semiconductors, resonating with searches for "nitro-aromatics in electronics."

Market insights indicate steady growth for 1-(2-Methoxyethoxy)-4-nitrobenzene, driven by Asia-Pacific pharmaceutical and agrochemical industries. Suppliers increasingly emphasize "custom synthesis services" and "scalable production" to meet diverse client needs. Regulatory compliance, particularly concerning workplace safety (e.g., OSHA standards), remains a priority, as evidenced by searches for "safe handling of nitrobenzene derivatives."

In summary, 1-(2-Methoxyethoxy)-4-nitrobenzene (CAS No. 22483-40-5) bridges multiple industries through its synthetic flexibility and functional adaptability. Its alignment with sustainability goals and high-value applications ensures continued relevance in scientific and industrial discourse.

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