Cas no 2248298-16-8 (2-(3,4-Dimethyl-2,3-dihydro-1H-inden-1-yl)propan-1-amine)

2-(3,4-Dimethyl-2,3-dihydro-1H-inden-1-yl)propan-1-amine is a synthetic organic compound featuring a substituted indane core with an amine functional group. Its structural framework, incorporating both aromatic and aliphatic components, lends versatility in chemical synthesis and potential applications in pharmaceutical or agrochemical research. The presence of the amine group enhances reactivity, enabling derivatization for further functionalization. The dimethyl substitution on the dihydroindene ring may influence steric and electronic properties, potentially improving selectivity in target interactions. This compound is of interest in medicinal chemistry due to its scaffold, which is amenable to modifications for probing structure-activity relationships. Handling requires standard precautions for amine-containing compounds.
2-(3,4-Dimethyl-2,3-dihydro-1H-inden-1-yl)propan-1-amine structure
2248298-16-8 structure
Product Name:2-(3,4-Dimethyl-2,3-dihydro-1H-inden-1-yl)propan-1-amine
CAS No:2248298-16-8
MF:C14H21N
MW:203.32324385643
CID:5880067
PubChem ID:137941071
Update Time:2025-05-19

2-(3,4-Dimethyl-2,3-dihydro-1H-inden-1-yl)propan-1-amine Chemical and Physical Properties

Names and Identifiers

    • EN300-6506658
    • 2248298-16-8
    • 2-(3,4-Dimethyl-2,3-dihydro-1H-inden-1-yl)propan-1-amine
    • Inchi: 1S/C14H21N/c1-9-5-4-6-12-13(11(3)8-15)7-10(2)14(9)12/h4-6,10-11,13H,7-8,15H2,1-3H3
    • InChI Key: GPVYOVKDTYIDAF-UHFFFAOYSA-N
    • SMILES: NCC(C)C1C2C=CC=C(C)C=2C(C)C1

Computed Properties

  • Exact Mass: 203.167399674g/mol
  • Monoisotopic Mass: 203.167399674g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 15
  • Rotatable Bond Count: 2
  • Complexity: 213
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 3
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3.1
  • Topological Polar Surface Area: 26?2

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Additional information on 2-(3,4-Dimethyl-2,3-dihydro-1H-inden-1-yl)propan-1-amine

2-(3,4-Dimethyl-2,3-dihydro-1H-inden-1-yl)propan-1-amine

2-(3,4-Dimethyl-2,3-dihydro-1H-inden-1-yl)propan-1-amine, also known by its CAS number 2248298-16-8, is a compound of significant interest in the fields of organic chemistry and materials science. This compound is a derivative of indene, a bicyclic aromatic hydrocarbon, with additional substituents that enhance its chemical reactivity and functional versatility. The structure of this compound consists of a central indenyl group substituted with two methyl groups at the 3 and 4 positions, which are further connected to a propylamine moiety. This unique combination of structural features makes it a valuable building block for various applications in drug discovery, polymer synthesis, and catalysis.

Recent studies have highlighted the potential of indene derivatives in the development of advanced materials. For instance, researchers have explored the use of indene-based polymers in the creation of high-performance electronics and optoelectronic devices. The presence of the propylamine group in 2-(3,4-Dimethyl-2,3-dihydro-1H-inden-1-yl)propan-1-amine introduces additional functional groups that can participate in various chemical reactions, such as amidation and alkylation. These reactions are crucial for modifying the physical and chemical properties of the compound to suit specific applications.

The synthesis of 2-(3,4-Dimethyl-2,3-dihydro-1H-inden-1-yl)propan-1-amine typically involves multi-step processes that require precise control over reaction conditions. One common approach is the Friedel-Crafts alkylation or acylation of indene derivatives followed by subsequent functionalization to introduce the amine group. Recent advancements in catalytic methods have enabled more efficient and selective syntheses, reducing production costs and minimizing environmental impact.

In terms of applications, indene derivatives like CAS 2248298-16-8 have found utility in pharmaceutical research due to their potential as scaffolds for bioactive molecules. For example, studies have shown that certain indene-based compounds exhibit anti-inflammatory and anticancer properties. The propylamine group in this compound can act as a hydrogen bond donor or acceptor, enhancing its ability to interact with biological targets such as enzymes and receptors.

Moreover, the indene core provides rigidity and planarity to the molecule, which are desirable properties for applications in nanotechnology and materials science. Researchers have investigated the use of such compounds in the development of self-assembled monolayers and supramolecular structures. The ability to modify the substituents on the indene ring further expands its potential for tailoring surface properties for specific uses.

From an environmental standpoint, understanding the fate and behavior of CAS 2248298-16-8 in various ecosystems is critical for assessing its safety and sustainability. Recent toxicological studies have focused on evaluating its potential toxicity to aquatic organisms and its biodegradability under different conditions. These studies are essential for ensuring that industrial applications do not pose significant risks to environmental health.

In conclusion, 2-(3,4-Dimethyl

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