• 1. Ester-directed orthogonal dual C–H activation and ortho aryl C–H alkenylation via distal weak coordination?
  Manickam Bakthadoss,Tadiparthi Thirupathi Reddy,Vishal Agarwal,Duddu S. Sharada Chem. Commun., 2022,58, 1406-1409
• 2. Distinction of trans–cis photoisomers with comparable optical properties in multiple-state photochromic systems – examining a molecule with three azobenzenes via in situ irradiation NMR spectroscopy?
  Jonas Kind,Lukas Kaltschnee,Martin Leyendecker,Christina M. Thiele Chem. Commun., 2016,52, 12506-12509
• 3. Evolution of shape, size, and areal density of a single plane of Si nanocrystals embedded in SiO2 matrix studied by atom probe tomography
  Bin Han,Yasuo Shimizu,Gabriele Seguini,Celia Castro,Gérard Ben Assayag,Koji Inoue,Yasuyoshi Nagai,Sylvie Schamm-Chardon,Michele Perego RSC Adv., 2016,6, 3617-3622
• 4. Dissolved oxygen sensor based on fluorescence quenching of oxygen-sensitive ruthenium complexes immobilized in sol–gel-derived porous silica coatings
  Analyst, 1996,121, 785-788
• 5. Exciton manipulation in rippled transition metal dichalcogenides?
  Chen Long,Ying Dai,Jianwei Li,Hao Jin Nanoscale, 2020,12, 21124-21130

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Halobenzenes Fluorobenzenes

Comprehensive Overview of 4-(4-Fluorophenyl)-1-butene (CAS No. 2248-13-7): Properties, Applications, and Industry Insights

4-(4-Fluorophenyl)-1-butene (CAS No. 2248-13-7) is a fluorinated organic compound with significant relevance in pharmaceutical and material science research. This unsaturated hydrocarbon, featuring a fluorophenyl group attached to a butene chain, has garnered attention due to its unique chemical properties and versatility in synthetic applications. The presence of the fluorine substituent enhances its reactivity, making it a valuable intermediate in the development of advanced materials and bioactive molecules.

In recent years, the demand for fluorinated compounds like 4-(4-Fluorophenyl)-1-butene has surged, driven by their applications in drug discovery and agrochemical formulations. Researchers are particularly interested in its role as a building block for PET imaging agents and liquid crystal materials, aligning with the growing focus on precision medicine and sustainable electronics. The compound’s CAS registry number (2248-13-7) is frequently searched in chemical databases, reflecting its industrial importance.

From a structural perspective, 4-(4-Fluorophenyl)-1-butene combines the electronic effects of fluorine with the flexibility of an aliphatic chain, enabling tailored modifications for specific applications. Its boiling point, solubility, and stability under various conditions are critical parameters for researchers optimizing synthetic routes. Environmental and regulatory trends also highlight the need for greener synthesis methods, prompting studies on catalytic fluorination techniques to produce such compounds more sustainably.

The compound’s relevance extends to high-performance polymers, where its incorporation can improve thermal resistance and optical properties. As industries shift toward bio-based alternatives, 4-(4-Fluorophenyl)-1-butene is being explored for compatibility with renewable feedstocks. This aligns with global searches for "eco-friendly fluorochemicals" and "green chemistry solutions," underscoring its potential in circular economy models.

Analytical techniques like GC-MS and NMR spectroscopy are essential for characterizing CAS No. 2248-13-7, ensuring purity and consistency in research. Safety data sheets emphasize standard laboratory precautions, though it is not classified as hazardous under normal handling conditions. The compound’s supply chain dynamics are also a topic of interest, with manufacturers focusing on scalable production to meet rising demand from Asia-Pacific and North American markets.

In summary, 4-(4-Fluorophenyl)-1-butene exemplifies the intersection of innovation and practicality in modern chemistry. Its applications span life sciences, electronics, and materials engineering, making it a compound of enduring scientific and commercial value. Ongoing research into its derivatives continues to unlock new possibilities, reinforcing its status as a cornerstone of fluoroorganic chemistry.

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• 222640-88-2(Benzene,1-(2E)-2-buten-1-yl-4-fluoro-)
• 61668-03-9(Benzene, 1,1'-(3-butenylidene)bis[4-fluoro-)
• 702-08-9(1-fluoro-4-(2-methylprop-2-enyl)benzene)
• 361979-99-9(Benzene, 1-fluoro-4-(1-methyl-3-butenyl)- (9CI))
• 225240-58-4( )
• 79538-22-0(1,3-difluoro-5-prop-2-en-1-ylbenzene)
• 405-64-1(Benzene,1-fluoro-4-propyl-)
• 731773-07-2(Benzene,1-fluoro-3-(3-methyl-3-buten-1-yl)-)
• 731773-12-9(4-(4-Fluorophenyl)-2-methyl-1-butene)