Cas no 224185-19-7 (1-bromo-2-fluoro-4-methyl-5-nitro-benzene)

1-Bromo-2-fluoro-4-methyl-5-nitro-benzene is a halogenated aromatic compound with a nitro substituent, offering versatile reactivity for synthetic applications. Its bromo and fluoro groups provide distinct electrophilic sites for nucleophilic substitution reactions, while the nitro group enhances electron-withdrawing properties, facilitating further functionalization. The methyl group contributes to steric and electronic modulation, making it useful in the synthesis of pharmaceuticals, agrochemicals, and advanced materials. This compound is particularly valuable as an intermediate in cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, due to its well-defined reactivity profile. High purity and stability under standard conditions ensure reliable performance in organic synthesis.
1-bromo-2-fluoro-4-methyl-5-nitro-benzene structure
224185-19-7 structure
Product Name:1-bromo-2-fluoro-4-methyl-5-nitro-benzene
CAS No:224185-19-7
MF:C7H5BrFNO2
MW:234.0225045681
MDL:MFCD04039299
CID:67070
PubChem ID:2779365
Update Time:2025-05-28

1-bromo-2-fluoro-4-methyl-5-nitro-benzene Chemical and Physical Properties

Names and Identifiers

    • 4-Bromo-5-fluoro-2-nitrotoluene
    • 1-bromo-2-fluoro-4-methyl-5-nitrobenzene
    • 1-Bromo-2-fluoro-4-methyl-5-nitro-benzene
    • 2-Nitro-4-Bromo-5-Fluorotoluene
    • 3-bromo-4-fluoro-6-methylnitrobenzene
    • 4-BROMO-3-FLUORO-6-NITROTOLUENE
    • Benzene, 1-bromo-2-fluoro-4-methyl-5-nitro-
    • 4-bromo-5-fluoro-1-methyl-2-nitrobenzene
    • PubChem3991
    • zlchem 1176
    • 3-FLUORO-4-BROMO-6-NITROTOLUENE
    • KSC549I4P
    • Jsp004555
    • ZLD0645
    • MTTNTJRJOFVWSY-UHFFFAOYSA-N
    • EBD13270
    • SBB063272
    • W-206760
    • AC-2354
    • 4-Bromo-5-fluoro-2-nitrotoluene, 97%
    • EN300-173908
    • 224185-19-7
    • AKOS025243443
    • AS-15027
    • AM20030384
    • FT-0644054
    • A19631
    • SCHEMBL451039
    • SY020679
    • MFCD04039299
    • AKOS015888465
    • CS-W007952
    • DTXSID70381414
    • 1-bromo-2-fluoro-4-methyl-5-nitro-benzene
    • MDL： MFCD04039299
    • Inchi： 1S/C7H5BrFNO2/c1-4-2-6(9)5(8)3-7(4)10(11)12/h2-3H,1H3
    • InChI Key： MTTNTJRJOFVWSY-UHFFFAOYSA-N
    • SMILES： BrC1C(=CC(C)=C(C=1)[N+](=O)[O-])F

Computed Properties

  • Exact Mass: 232.94900
  • Monoisotopic Mass: 232.949
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 0
  • Complexity: 185
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: 2.9
  • Topological Polar Surface Area: 45.8

Experimental Properties

  • Color/Form: YELLOW SOLID
  • Density: 1.224
  • Melting Point: 59-63 °C
  • Boiling Point: 337.5℃ at 760 mmHg
  • Flash Point: 24°C
  • Refractive Index: 1.57
  • PSA: 45.82000
  • LogP: 3.32800
  • Solubility: Insoluble in water

1-bromo-2-fluoro-4-methyl-5-nitro-benzene Security Information

  • Symbol: GHS07
  • Signal Word：Warning
  • Hazard Statement： H302,H319
  • Warning Statement： P305+P351+P338
  • Hazardous Material transportation number：NONH for all modes of transport
  • WGK Germany：3
  • Hazard Category Code： 22-36
  • Safety Instruction： S26-S36/37
  • Hazardous Material Identification： Xn
  • Safety Term：S26;S36/37
  • Storage Condition：Room temperature
  • Risk Phrases：R22; R36

1-bromo-2-fluoro-4-methyl-5-nitro-benzene Customs Data

  • HS CODE：2904909090
  • Customs Data：

    China Customs Code:

    2904909090

    Overview:

    2904909090 Sulfonation of other hydrocarbons\nitrification\Nitrosative derivative(Whether halogenated or not). VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:5.5% general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    HS:2904909090 sulphonated, nitrated or nitrosated derivatives of hydrocarbons, whether or not halogenated VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

1-bromo-2-fluoro-4-methyl-5-nitro-benzene Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
SHANG HAI XIAN DING Biotechnology Co., Ltd.
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 224185-19-7 95+%
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XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd.
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TRC
B692763-100mg
4-Bromo-5-fluoro-2-nitrotoluene
 224185-19-7
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 $ 64.00 2023-04-18
TRC
B692763-250mg
4-Bromo-5-fluoro-2-nitrotoluene
 224185-19-7
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 $ 75.00 2023-04-18
TRC
B692763-500mg
4-Bromo-5-fluoro-2-nitrotoluene
 224185-19-7
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 $ 87.00 2023-04-18
TRC
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4-Bromo-5-fluoro-2-nitrotoluene
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SHANG HAI YI EN HUA XUE JI SHU Co., Ltd.
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