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Comprehensive Overview of 1-(2,6-Dichloro-3-nitrophenyl)ethanone (CAS No. 223785-76-0): Properties, Applications, and Industry Insights

1-(2,6-Dichloro-3-nitrophenyl)ethanone, with the CAS number 223785-76-0, is a specialized organic compound widely recognized for its role in pharmaceutical and agrochemical synthesis. This nitrophenyl derivative features a unique molecular structure, combining a dichloro-substituted benzene ring with a nitro group and an acetyl moiety. Its high purity and reactivity make it invaluable for constructing complex molecules, particularly in drug discovery and crop protection formulations.

In recent years, the demand for 1-(2,6-Dichloro-3-nitrophenyl)ethanone has surged due to its applications in developing next-generation APIs (Active Pharmaceutical Ingredients). Researchers frequently search for "CAS 223785-76-0 solubility" or "synthetic routes for nitrophenyl ketones," reflecting its technical significance. The compound's electron-withdrawing groups enhance its utility in cross-coupling reactions, a hot topic in green chemistry discussions.

From an industrial perspective, 1-(2,6-Dichloro-3-nitrophenyl)ethanone aligns with the growing focus on sustainable synthesis. Laboratories optimizing "eco-friendly nitration methods" often employ this intermediate. Its melting point (128-131°C) and molecular weight (248.05 g/mol) are critical parameters for quality control, as evidenced by frequent queries like "CAS 223785-76-0 specifications" in analytical databases.

The compound's structural versatility also attracts attention in material science. Studies exploring "nitroaromatics for OLEDs" highlight its potential in electronic materials. When handling 1-(2,6-Dichloro-3-nitrophenyl)ethanone, proper storage conditions (e.g., inert atmosphere) are essential to maintain stability—a key concern for purchasers searching for "223785-76-0 handling guidelines."

Innovative applications continue to emerge, particularly in photocatalysis and bioconjugation. The nitro group's reducibility enables selective transformations, addressing the pharmaceutical industry's need for "selective functionalization techniques." Regulatory-compliant synthesis remains a priority, with searches for "GMP-grade nitrophenyl intermediates" reflecting market trends.

Analytical characterization of CAS 223785-76-0 typically involves HPLC, GC-MS, and NMR spectroscopy. Recent publications on "advanced spectral analysis of halogenated ketones" underscore its analytical complexity. Suppliers emphasizing batch-to-batch consistency gain traction, as evidenced by procurement teams evaluating "223785-76-0 supplier QC data."

Future research directions may explore its catalytic applications or modifications to enhance biodegradability—topics gaining traction in "green chemistry forums." As synthetic methodologies evolve, 1-(2,6-Dichloro-3-nitrophenyl)ethanone will likely maintain its status as a high-value building block for multidisciplinary innovation.

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