• 1. Fast synthesis of red Li3BaSrLn3(WO4)8:Eu3+ phosphors for white LEDs under near-UV excitation by a microwave-assisted solid state reaction method and photoluminescence studies
  Bo Wei,Zhenyu Liu,Chen Xie,Shu Yang,Wentao Tang,Aiwei Gu,Wing-Tak Wong,Ka-Leung Wong J. Mater. Chem. C, 2015,3, 12322-12327
• 2. Evolution of important glucosinolates in three common Brassica vegetables during their processing into vegetable powder and in vitro gastric digestion
  Nan Fu,Naphaporn Chiewchan,Xiao Dong Chen Food Funct., 2020,11, 211-220
• 3. Evolution in surface coverage of CH3NH3PbI3?XClXvia heat assisted solvent vapour treatment and their effects on photovoltaic performance of devices
  Dhirendra K. Chaudhary,Pramendra Kumar,Lokendra Kumar RSC Adv., 2016,6, 94731-94738
• 4. Emulsion soft templating of carbide-derived carbon nanospheres with controllable porosity for capacitive electrochemical energy storage?
  M. Zeiger,N. J?ckel,P. Strubel,L. Borchardt,R. Reinhold,W. Nickel,J. Eckert,V. Presser,S. Kaskel J. Mater. Chem. A, 2015,3, 17983-17990
• 5. Fatty acid positional distribution in colostrum and mature milk of women living in Inner Mongolia, North Jiangsu and Guangxi of China?
  Long Deng,Qian Zou,Biao Liu,Wenhui Ye,Chengfei Zhuo,Li Chen,Ze-Yuan Deng,Ya-Wei Fan,Jing Li Food Funct., 2018,9, 4234-4245

Comprehensive Guide to 2,2,2-Trifluoro-1-(1-methyl-1H-indol-6-yl)ethan-1-ol (CAS No. 2229343-89-7): Properties, Applications, and Market Insights

2,2,2-Trifluoro-1-(1-methyl-1H-indol-6-yl)ethan-1-ol (CAS No. 2229343-89-7) is a fluorinated indole derivative gaining attention in pharmaceutical and agrochemical research. This compound, characterized by its trifluoromethyl group and indole backbone, exhibits unique physicochemical properties that make it valuable for drug discovery and material science applications.

The molecular structure of 2,2,2-trifluoro-1-(1-methyl-1H-indol-6-yl)ethan-1-ol combines the electron-withdrawing properties of fluorine atoms with the versatile indole scaffold, creating a compound with interesting hydrogen-bonding capabilities. Researchers are particularly interested in its potential as a building block for bioactive molecules, given the increasing demand for fluorinated compounds in modern medicinal chemistry.

Recent studies highlight the compound's relevance in developing novel kinase inhibitors, a hot topic in cancer research. The trifluoroethanol moiety contributes to enhanced binding affinity and metabolic stability, addressing key challenges in drug development. Pharmaceutical companies are exploring derivatives of CAS 2229343-89-7 for targeted therapies, especially in oncology and neurological disorders.

In material science, 2,2,2-trifluoro-1-(1-methyl-1H-indol-6-yl)ethan-1-ol serves as a precursor for advanced fluorinated polymers with improved thermal stability and chemical resistance. The growing demand for high-performance materials in electronics and aerospace industries has increased interest in such fluorinated intermediates.

The synthesis of 2,2,2-trifluoro-1-(1-methyl-1H-indol-6-yl)ethan-1-ol typically involves multi-step organic reactions, with researchers continuously optimizing routes for better yields and sustainability. Green chemistry approaches using catalytic fluorination methods are becoming particularly relevant, aligning with current industry trends toward environmentally friendly processes.

Analytical characterization of CAS 2229343-89-7 employs advanced techniques including NMR spectroscopy, mass spectrometry, and X-ray crystallography. These methods confirm the compound's purity and structural features, essential for research applications. The compound typically appears as a white to off-white crystalline solid with specific melting point characteristics.

Market analysis indicates growing demand for fluorinated indole derivatives, with 2,2,2-trifluoro-1-(1-methyl-1H-indol-6-yl)ethan-1-ol positioned as a valuable intermediate. Pharmaceutical and agrochemical sectors drive this demand, particularly in regions with strong R&D infrastructure like North America, Europe, and parts of Asia.

Storage and handling of 2,2,2-trifluoro-1-(1-methyl-1H-indol-6-yl)ethan-1-ol require standard laboratory precautions. While not classified as highly hazardous, proper ventilation and personal protective equipment are recommended when working with this compound, as with all fine chemicals.

Future research directions for CAS 2229343-89-7 include exploring its potential in PET radiopharmaceuticals (given the fluorine content) and as a scaffold for proteolysis targeting chimeras (PROTACs), both cutting-edge areas in drug discovery. The compound's versatility suggests it will remain relevant as new applications emerge in chemical biology and materials science.

For researchers sourcing 2,2,2-trifluoro-1-(1-methyl-1H-indol-6-yl)ethan-1-ol, quality specifications including purity levels (typically ≥95% by HPLC) and batch-to-batch consistency are critical factors. Reputable suppliers provide comprehensive analytical data and proper documentation to support research applications.

• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)