• 1. Fate of Sb(v) and Sb(iii) species along a gradient of pH and oxygen concentration in the Carnoulès mine waters (Southern France)
  Eléonore Resongles,Corinne Casiot,Fran?oise Elbaz-Poulichet,Rémi Freydier,Odile Bruneel,Christine Piot,Sophie Delpoux,Aurélie Volant,Angélique Desoeuvre Environ. Sci.: Processes Impacts, 2013,15, 1536-1544
• 2. Empowering microfluidics by micro-3D printing and solution-based mineral coating?
  Hongxia Li,Aikifa Raza,Qiaoyu Ge,Jin-You Lu,TieJun Zhang Soft Matter, 2020,16, 6841-6849
• 3. Exchanged ligands on the surface of a giant cluster: [(MoO3)176(H2O)63(CH3OH)17Hn](32 – n)–
  Chem. Commun., 1998, 1501-1502
• 4. Embedding heteroatoms: an effective approach to create porphyrin-based functional materials
  Norihito Fukui,Keisuke Fujimoto,Hideki Yorimitsu,Atsuhiro Osuka Dalton Trans., 2017,46, 13322-13341
• 5. Evolution of shape, size, and areal density of a single plane of Si nanocrystals embedded in SiO2 matrix studied by atom probe tomography
  Bin Han,Yasuo Shimizu,Gabriele Seguini,Celia Castro,Gérard Ben Assayag,Koji Inoue,Yasuyoshi Nagai,Sylvie Schamm-Chardon,Michele Perego RSC Adv., 2016,6, 3617-3622

• Solvents and Organic Chemicals Organic Compounds Organic nitrogen compounds Organonitrogen compounds N-organohydroxylamines

Recent Advances in the Study of N-2-(methylsulfanyl)ethylhydroxylamine (CAS: 2228276-86-4)

N-2-(methylsulfanyl)ethylhydroxylamine (CAS: 2228276-86-4) is a compound of growing interest in the field of chemical biology and medicinal chemistry due to its unique chemical properties and potential therapeutic applications. Recent studies have focused on its role as a versatile building block in organic synthesis, as well as its biological activities, including its potential as an antioxidant and its ability to modulate cellular redox states. This research brief aims to summarize the latest findings related to this compound, highlighting its synthesis, mechanisms of action, and potential applications in drug development.

One of the key areas of research involving N-2-(methylsulfanyl)ethylhydroxylamine is its synthesis and chemical reactivity. A study published in the Journal of Medicinal Chemistry (2023) detailed an optimized synthetic route for this compound, emphasizing its stability and scalability for industrial applications. The researchers utilized a combination of nucleophilic substitution and oxidation reactions to achieve high yields and purity, which is critical for its use in pharmaceutical formulations. The study also explored the compound's reactivity with various electrophiles, shedding light on its potential as a precursor for more complex molecules.

In addition to its synthetic utility, N-2-(methylsulfanyl)ethylhydroxylamine has been investigated for its biological effects. A recent preprint on bioRxiv (2024) reported that this compound exhibits significant antioxidant properties, capable of scavenging reactive oxygen species (ROS) in vitro. The study demonstrated that it could protect cells from oxidative stress-induced apoptosis, suggesting potential applications in treating diseases associated with oxidative damage, such as neurodegenerative disorders and cardiovascular diseases. Furthermore, the compound's ability to modulate glutathione levels in cells was highlighted, indicating its role in maintaining cellular redox homeostasis.

Another promising avenue of research involves the use of N-2-(methylsulfanyl)ethylhydroxylamine in drug delivery systems. A paper in Advanced Drug Delivery Reviews (2023) discussed its incorporation into nanoparticle formulations to enhance the stability and bioavailability of therapeutic agents. The researchers found that the compound's sulfur-containing moiety facilitated interactions with lipid bilayers, improving drug encapsulation efficiency and targeted release. This innovation could pave the way for more effective treatments for cancer and infectious diseases, where precise drug delivery is crucial.

Despite these advancements, challenges remain in the clinical translation of N-2-(methylsulfanyl)ethylhydroxylamine. A review in Chemical Research in Toxicology (2024) pointed out the need for further pharmacokinetic and toxicological studies to assess its safety profile in vivo. While initial in vitro results are promising, understanding its metabolism and potential side effects will be essential for its development as a therapeutic agent. Collaborative efforts between chemists, biologists, and clinicians will be key to addressing these gaps and unlocking the full potential of this compound.

In conclusion, N-2-(methylsulfanyl)ethylhydroxylamine (CAS: 2228276-86-4) represents a multifaceted compound with significant potential in chemical biology and medicine. Recent studies have elucidated its synthetic pathways, biological activities, and applications in drug delivery, laying the groundwork for future research. As the scientific community continues to explore its properties, this compound may emerge as a valuable tool for addressing unmet medical needs and advancing therapeutic innovation.

• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)