Cas no 22279-89-6 (2,5-Dimethylpyridin-4-amine)

2,5-Dimethylpyridin-4-amine is a substituted pyridine derivative featuring amine and methyl functional groups at the 4- and 2,5-positions, respectively. This compound serves as a versatile intermediate in organic synthesis, particularly in the preparation of pharmaceuticals, agrochemicals, and coordination complexes. Its electron-rich aromatic system and nucleophilic amine group enable selective functionalization, making it valuable for constructing heterocyclic frameworks. The methyl substituents enhance steric and electronic properties, influencing reactivity and stability. With a well-defined structure and high purity, 2,5-Dimethylpyridin-4-amine is suitable for precise applications in medicinal chemistry and material science. Proper handling under inert conditions is recommended due to potential sensitivity to air or moisture.
2,5-Dimethylpyridin-4-amine structure
2,5-Dimethylpyridin-4-amine structure
Product Name:2,5-Dimethylpyridin-4-amine
CAS No:22279-89-6
MF:C7H10N2
MW:122.167701244354
MDL:MFCD00235163
CID:250636
PubChem ID:4175799
Update Time:2025-05-19

2,5-Dimethylpyridin-4-amine Chemical and Physical Properties

Names and Identifiers

    • 2,5-Dimethylpyridin-4-amine
    • 4-Amino-2,5-dimethylpyridine
    • 4-Pyridinamine,2,5-dimethyl-
    • 1,5-Dimethyl-4-aminopyridin
    • 2,5-DIMETHYL-4-PYRIDINAMINE
    • 2,5-dimethyl-pyridin-4-ylamine
    • 4 -amino-2.5 -dimethylpyridine
    • 4-Amino-2,5-dimethyl-pyridin
    • 4-amino-2,5-lutidine
    • AB05308
    • AC1N4AHZ
    • SureCN7054061
    • 4-Pyridinamine,2,5-dimethyl-(9CI)
    • 2,5-dimethyl-4-aminopyridine
    • KQCWCIYVDIVYAB-UHFFFAOYSA-N
    • NE20778
    • 4-PYRIDINAMINE, 2,5-DIMETHYL-
    • AK126931
    • Z1480642774
    • MDL: MFCD00235163
    • Inchi: 1S/C7H10N2/c1-5-4-9-6(2)3-7(5)8/h3-4H,1-2H3,(H2,8,9)
    • InChI Key: KQCWCIYVDIVYAB-UHFFFAOYSA-N
    • SMILES: N1C=C(C)C(=CC=1C)N

Computed Properties

  • Exact Mass: 122.0845
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 9
  • Rotatable Bond Count: 0
  • Complexity: 92.9
  • Topological Polar Surface Area: 38.9

Experimental Properties

  • PSA: 38.91

2,5-Dimethylpyridin-4-amine Security Information

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Additional information on 2,5-Dimethylpyridin-4-amine

2,5-Dimethylpyridin-4-amine: A Comprehensive Overview

2,5-Dimethylpyridin-4-amine, also known by its CAS registry number CAS No: 22279-89-6, is a heterocyclic aromatic amine compound with significant applications in various fields of chemistry and materials science. This compound has garnered attention due to its unique structural properties and potential for use in advanced materials and pharmaceuticals. In this article, we will delve into the structural characteristics, synthesis methods, applications, and recent research findings related to 2,5-Dimethylpyridin-4-amine.

The molecular structure of 2,5-Dimethylpyridin-4-amine consists of a pyridine ring with methyl groups at positions 2 and 5 and an amino group at position 4. This arrangement imparts the compound with distinct electronic properties, making it suitable for various chemical reactions and applications. The presence of the amino group at position 4 introduces nucleophilic character to the molecule, while the methyl groups at positions 2 and 5 provide steric bulk and influence the overall reactivity of the compound.

Recent studies have explored the synthesis of 2,5-Dimethylpyridin-4-amine through various routes, including condensation reactions and catalytic processes. One notable approach involves the reaction of o-xylene with ammonia in the presence of a catalyst to form a precursor intermediate, which is then subjected to further transformations to yield the desired product. Researchers have also investigated the use of microwave-assisted synthesis techniques to enhance reaction efficiency and reduce reaction times.

The applications of 2,5-Dimethylpyridin-4-amine span across multiple domains. In materials science, it has been employed as a building block for constructing advanced materials such as coordination polymers and metal organic frameworks (MOFs). These materials exhibit exceptional porosity and stability, making them ideal candidates for gas storage and separation applications. Additionally, 2,5-Dimethylpyridin-4-amine has shown promise in drug design due to its ability to act as a bioisostere or a scaffold for developing bioactive molecules.

In the field of catalysis, 2,5-Dimethylpyridin-4-amine has been utilized as a ligand in transition metal catalysts for various organic transformations. Its ability to coordinate with metal centers enhances catalytic activity and selectivity in reactions such as cross-couplings and hydrogenations. Recent research has focused on optimizing ligand structures to improve catalyst performance under mild reaction conditions.

The unique electronic properties of 2,5-Dimethylpyridin-4-amine also make it a valuable component in electrochemical applications. It has been incorporated into electrode materials for batteries and supercapacitors due to its high conductivity and redox activity. Researchers have reported enhanced energy storage capabilities when this compound is integrated into carbon-based electrodes.

In terms of environmental applications, 2,5-Dimethylpyridin-4-amine has been studied for its potential role in pollution control technologies. It has been used as an adsorbent for removing heavy metal ions from aqueous solutions due to its strong chelating ability. Recent studies have demonstrated high adsorption capacities for metals such as lead (Pb2?) and cadmium (Cd2?), highlighting its potential in water treatment processes.

The versatility of CAS No: 22279-89-6, or 2,5-Dimethylpyridin-4-Amine, lies in its ability to serve as both a functional material and a chemical precursor. Its applications continue to expand as researchers uncover new ways to harness its unique properties across diverse fields.

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