Cas no 2225170-63-6 ((2-chloro-4-cyclopropyl-5-methylphenyl)boronic acid)
(2-Chloro-4-cyclopropyl-5-methylphenyl)boronic acid is a boronic acid derivative featuring a chloro-substituted aromatic ring with cyclopropyl and methyl functional groups. This compound is primarily utilized as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the synthesis of biaryl structures with high selectivity and efficiency. Its sterically hindered aromatic ring enhances reactivity in challenging coupling conditions while maintaining stability. The presence of the cyclopropyl group offers additional versatility in medicinal chemistry applications. The compound is typically supplied as a stable, crystalline solid with consistent purity, ensuring reliable performance in synthetic workflows. Proper storage under inert conditions is recommended to preserve its reactivity.
2225170-63-6 structure
Product Name:(2-chloro-4-cyclopropyl-5-methylphenyl)boronic acid
CAS No:2225170-63-6
MF:C10H12BClO2
MW:210.47
MDL:MFCD24449148
CID:5142357
PubChem ID:133634859
Update Time:2025-05-28
(2-chloro-4-cyclopropyl-5-methylphenyl)boronic acid Chemical and Physical Properties
Names and Identifiers
-
- 2-Chloro-5-methyl-4-cyclopropylphenylboronic acid
- (2-chloro-4-cyclopropyl-5-methylphenyl)boronic acid
- (2-chloro-4-cyclopropyl-5-methylphenyl)boronicacid
- 2225170-63-6
- EN300-3228558
- Z1681364716
-
- MDL： MFCD24449148
- Inchi： 1S/C10H12BClO2/c1-6-4-9(11(13)14)10(12)5-8(6)7-2-3-7/h4-5,7,13-14H,2-3H2,1H3
- InChI Key： DVGOFIZBAWEZTL-UHFFFAOYSA-N
- SMILES： C1(B(O)O)=CC(C)=C(C2CC2)C=C1Cl
Computed Properties
- Exact Mass: 210.0618875g/mol
- Monoisotopic Mass: 210.0618875g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 14
- Rotatable Bond Count: 2
- Complexity: 208
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 40.5?2
(2-chloro-4-cyclopropyl-5-methylphenyl)boronic acid Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | C904941-25mg |
2-Chloro-5-methyl-4-cyclopropylphenylboronic acid |
2225170-63-6 | 95% | 25mg |
￥2,790.00 | 2022-09-02 | |
| Enamine | EN300-3228558-1g |
(2-chloro-4-cyclopropyl-5-methylphenyl)boronic acid |
2225170-63-6 | 95% | 1g |
$1329.0 | 2023-09-04 | |
| Enamine | EN300-3228558-5g |
(2-chloro-4-cyclopropyl-5-methylphenyl)boronic acid |
2225170-63-6 | 95% | 5g |
$3852.0 | 2023-09-04 | |
| Enamine | EN300-3228558-10g |
(2-chloro-4-cyclopropyl-5-methylphenyl)boronic acid |
2225170-63-6 | 95% | 10g |
$5712.0 | 2023-09-04 | |
| Enamine | EN300-3228558-0.05g |
(2-chloro-4-cyclopropyl-5-methylphenyl)boronic acid |
2225170-63-6 | 95.0% | 0.05g |
$309.0 | 2025-03-19 | |
| Enamine | EN300-3228558-0.1g |
(2-chloro-4-cyclopropyl-5-methylphenyl)boronic acid |
2225170-63-6 | 95.0% | 0.1g |
$461.0 | 2025-03-19 | |
| Enamine | EN300-3228558-0.25g |
(2-chloro-4-cyclopropyl-5-methylphenyl)boronic acid |
2225170-63-6 | 95.0% | 0.25g |
$659.0 | 2025-03-19 | |
| Enamine | EN300-3228558-0.5g |
(2-chloro-4-cyclopropyl-5-methylphenyl)boronic acid |
2225170-63-6 | 95.0% | 0.5g |
$1037.0 | 2025-03-19 | |
| Enamine | EN300-3228558-1.0g |
(2-chloro-4-cyclopropyl-5-methylphenyl)boronic acid |
2225170-63-6 | 95.0% | 1.0g |
$1329.0 | 2025-03-19 | |
| Enamine | EN300-3228558-2.5g |
(2-chloro-4-cyclopropyl-5-methylphenyl)boronic acid |
2225170-63-6 | 95.0% | 2.5g |
$2605.0 | 2025-03-19 |
(2-chloro-4-cyclopropyl-5-methylphenyl)boronic acid Related Literature
-
Yaling Zhang,Chunhui Dai,Shiwei Zhou,Bin Liu Chem. Commun., 2018,54, 10092-10095
-
Norihito Fukui,Keisuke Fujimoto,Hideki Yorimitsu,Atsuhiro Osuka Dalton Trans., 2017,46, 13322-13341
-
Ji-Ping Wei Nanoscale, 2015,7, 11815-11832
-
Jason Wan Lab Chip, 2020,20, 4528-4538
-
Yukiya Kitayama Polym. Chem., 2014,5, 2784-2792
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