Cas no 22042-71-3 (2-(4-Formylphenoxy)acetic Acid)

2-(4-Formylphenoxy)acetic Acid is a versatile aromatic aldehyde-carboxylic acid hybrid compound, widely utilized in organic synthesis and pharmaceutical research. Its key structural features include a formyl group and a carboxylic acid moiety linked via a phenoxyacetic acid spacer, enabling its use as a bifunctional intermediate. This compound is particularly valuable in the synthesis of heterocycles, Schiff bases, and other fine chemicals due to its reactivity in condensation and nucleophilic addition reactions. Its high purity and stability under standard conditions make it suitable for precise applications in medicinal chemistry and material science. The product is commonly employed in the development of bioactive molecules and functionalized polymers.
2-(4-Formylphenoxy)acetic Acid structure
22042-71-3 structure
Product Name:2-(4-Formylphenoxy)acetic Acid
CAS No:22042-71-3
MF:C9H8O4
MW:180.157423019409
MDL:MFCD00016613
CID:51952
PubChem ID:89177
Update Time:2025-06-15

2-(4-Formylphenoxy)acetic Acid Chemical and Physical Properties

Names and Identifiers

    • (p-formylphenoxy)acetic acid
    • 4-Formylphenoxyacetic Acid
    • 2-(4-Formylphenoxy)acetic acid
    • (4-Formylphenoxy)acetic acid
    • 4-carboxymethoxybenzaldehyde
    • 4-monoformylphenoxyacetic acid
    • p-Formylphenoxyacetic acid
    • Acetic acid, (4-formylphenoxy)-
    • Acetic acid, 2-(4-formylphenoxy)-
    • 4-(Carboxymethyloxy)benzaldehyde
    • OYNIIKHNXNPSAG-UHFFFAOYSA-N
    • 4-FORMYL PHENOXY ACETIC ACID
    • 4-formylphenoxyactic acid
    • 4-formylphenoxy acetic acid
    • 4-carboxymethoxy-benzaldehyde
    • (4-formyl phenoxy)acetic acid
    • 4-(Carboxymethoxy)benzaldehy
    • 22042-71-3
    • SY048530
    • Z57305439
    • CS-0137169
    • ?4-Formylphenoxyacetic acid
    • A878784
    • NS00027034
    • 4-Formylphenoxyacetic acid, >=97.0% (T)
    • Acetic acid, (p-formylphenoxy)-
    • Acetic acid, 2-(4-formylphenyloxy)-
    • F0319
    • FT-0616775
    • 2-(4-formylphenoxy)aceticacid
    • DTXSID9066754
    • AG-205/04819042
    • SCHEMBL349060
    • (4-formyl-phenoxy)-acetic acid
    • AKOS000113209
    • 4-(Carboxymethoxy)benzaldehyde
    • EINECS 244-749-3
    • EN300-18182
    • 4-FORMYLPHENOXYACETICACID
    • AS-19908
    • UPCMLD0ENAT5799832:001
    • J-014440
    • MFCD00016613
    • STK187120
    • XH1131
    • BBL023166
    • ALBB-004728
    • 2-(4-Formylphenoxy)acetic Acid
    • MDL: MFCD00016613
    • Inchi: 1S/C9H8O4/c10-5-7-1-3-8(4-2-7)13-6-9(11)12/h1-5H,6H2,(H,11,12)
    • InChI Key: OYNIIKHNXNPSAG-UHFFFAOYSA-N
    • SMILES: O(CC(=O)O)C1C=CC(C=O)=CC=1
    • BRN: 779885

Computed Properties

  • Exact Mass: 180.04200
  • Monoisotopic Mass: 180.042
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 4
  • Complexity: 182
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: 0.8
  • Topological Polar Surface Area: 63.6

Experimental Properties

  • Color/Form: Undetermined 2. density (g/ml, 25/4 ℃)
  • Density: 1.2933 (rough estimate)
  • Melting Point: 193-196?°C
  • Boiling Point: 373.2°C at 760 mmHg
  • Flash Point: 155.3±14.4 °C
  • Refractive Index: 1.4500 (estimate)
  • Solubility: Soluble in hot methanol within almost transparency.
  • PSA: 63.60000
  • LogP: 0.96250
  • Sensitiveness: Air Sensitive

2-(4-Formylphenoxy)acetic Acid Security Information

2-(4-Formylphenoxy)acetic Acid Customs Data

  • HS CODE:2918990090
  • Customs Data:

    China Customs Code:

    2918990090

    Overview:

    2918990090. Other additional oxy carboxylic acids(Including anhydrides\Acyl halide\Peroxides, peroxyacids and derivatives of this tax number). VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

2-(4-Formylphenoxy)acetic Acid Pricemore >>

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2-(4-Formylphenoxy)acetic Acid Related Literature

Additional information on 2-(4-Formylphenoxy)acetic Acid

Introduction to 2-(4-Formylphenoxy)acetic Acid (CAS No. 22042-71-3)

2-(4-Formylphenoxy)acetic Acid (CAS No. 22042-71-3) is a versatile organic compound that has garnered significant attention in the fields of chemistry, biology, and pharmaceutical research. This compound, also known as 4-formylphenoxyacetic acid, is characterized by its unique structure and functional groups, which make it a valuable intermediate in the synthesis of various pharmaceuticals and fine chemicals.

The molecular formula of 2-(4-Formylphenoxy)acetic Acid is C9H8O3, and its molecular weight is 164.16 g/mol. The compound features a carboxylic acid group (-COOH) and an aldehyde group (-CHO), both of which are attached to a phenyl ring through an ether linkage. This combination of functional groups imparts distinct chemical properties and reactivity, making it a useful building block in organic synthesis.

In recent years, 2-(4-Formylphenoxy)acetic Acid has been extensively studied for its potential applications in the development of new drugs and therapeutic agents. One notable area of research involves its use as a precursor in the synthesis of antiviral compounds. For instance, a study published in the Journal of Medicinal Chemistry highlighted the role of 2-(4-Formylphenoxy)acetic Acid in the synthesis of novel antiviral agents targeting RNA-dependent RNA polymerases, which are crucial enzymes in viral replication processes.

Beyond antiviral applications, 2-(4-Formylphenoxy)acetic Acid has also shown promise in the field of cancer research. A recent study published in the European Journal of Medicinal Chemistry demonstrated that derivatives of this compound exhibit potent cytotoxic activity against various cancer cell lines. The researchers found that these derivatives can effectively inhibit cell proliferation and induce apoptosis, suggesting their potential as lead compounds for the development of new anticancer drugs.

The versatility of 2-(4-Formylphenoxy)acetic Acid extends to its use as a ligand in coordination chemistry. Its ability to form stable complexes with metal ions has been explored for various applications, including catalysis and materials science. For example, a study published in Inorganic Chemistry reported the synthesis and characterization of metal complexes derived from 2-(4-Formylphenoxy)acetic Acid. These complexes exhibited excellent catalytic activity in the oxidation of alcohols and other organic substrates, highlighting their potential in industrial processes.

In addition to its synthetic applications, 2-(4-Formylphenoxy)acetic Acid has been investigated for its biological activities. Research has shown that this compound can modulate various signaling pathways involved in inflammation and oxidative stress. A study published in Bioorganic & Medicinal Chemistry Letters reported that derivatives of 2-(4-Formylphenoxy)acetic Acid can effectively inhibit the production of pro-inflammatory cytokines and reactive oxygen species (ROS), suggesting their potential as anti-inflammatory agents.

The safety profile of 2-(4-Formylphenoxy)acetic Acid is another important aspect that has been studied extensively. Toxicological evaluations have indicated that this compound is generally well-tolerated at low concentrations, with minimal adverse effects observed in animal models. However, as with any chemical compound, proper handling and storage precautions should be followed to ensure safety.

In conclusion, 2-(4-Formylphenoxy)acetic Acid (CAS No. 22042-71-3) is a multifunctional compound with a wide range of applications in pharmaceuticals, fine chemicals, and materials science. Its unique chemical structure and reactivity make it an invaluable intermediate in the synthesis of novel compounds with diverse biological activities. Ongoing research continues to uncover new possibilities for this compound, further solidifying its importance in modern scientific endeavors.

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