Cas no 219736-10-4 (1-cyclopropylpropan-1-amine)

1-Cyclopropylpropan-1-amine is a primary amine featuring a cyclopropyl substituent, offering a unique structural motif with applications in pharmaceutical and agrochemical synthesis. Its cyclopropyl group imparts enhanced steric and electronic properties, making it a valuable intermediate for designing bioactive molecules. The compound exhibits good stability under standard conditions and is compatible with a range of organic transformations, including reductive amination and nucleophilic substitutions. Its compact, rigid structure can influence conformational preferences in target molecules, potentially improving binding affinity or metabolic stability. Available in high purity, 1-cyclopropylpropan-1-amine is suitable for research and industrial-scale applications requiring precise amine functionalization.
1-cyclopropylpropan-1-amine structure
1-cyclopropylpropan-1-amine structure
Product Name:1-cyclopropylpropan-1-amine
CAS No:219736-10-4
MF:C6H13N
MW:99.1741216182709
MDL:MFCD05191939
CID:1072530
PubChem ID:3985879
Update Time:2025-10-30

1-cyclopropylpropan-1-amine Chemical and Physical Properties

Names and Identifiers

    • (1-Cyclopropylpropyl)amine
    • 1-cyclopropyl-propylamine
    • OXXSMQHKMPTBAR-UHFFFAOYSA-N
    • 1-cyclopropylpropan-1-amine
    • EN300-216055
    • AKOS010036518
    • 219736-10-4
    • DTXSID00398393
    • LS-05960
    • MFCD05191939
    • (1-Cyclopropylpropyl)amine, AldrichCPR
    • MDL: MFCD05191939
    • Inchi: 1S/C6H13N/c1-2-6(7)5-3-4-5/h5-6H,2-4,7H2,1H3
    • InChI Key: OXXSMQHKMPTBAR-UHFFFAOYSA-N
    • SMILES: NC(CC)C1CC1

Computed Properties

  • Exact Mass: 99.104799419g/mol
  • Monoisotopic Mass: 99.104799419g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 7
  • Rotatable Bond Count: 2
  • Complexity: 57.2
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1
  • Topological Polar Surface Area: 26?2

Experimental Properties

  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 124.9±8.0 °C at 760 mmHg
  • Flash Point: 23.3±13.3 °C
  • Vapor Pressure: 12.5±0.2 mmHg at 25°C

1-cyclopropylpropan-1-amine Security Information

1-cyclopropylpropan-1-amine Pricemore >>

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abcr
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Additional information on 1-cyclopropylpropan-1-amine

Comprehensive Overview of 1-Cyclopropylpropan-1-amine (CAS No. 219736-10-4): Properties, Applications, and Industry Insights

1-Cyclopropylpropan-1-amine (CAS No. 219736-10-4) is a specialized organic compound featuring a unique cyclopropyl ring attached to a propylamine backbone. This structural configuration endows it with distinct chemical properties, making it valuable in pharmaceutical research, agrochemical development, and material science. The compound's cyclopropyl group enhances its steric and electronic characteristics, which are critical for modulating biological activity or material performance. Researchers and industries increasingly focus on such amine derivatives due to their versatility in synthesizing bioactive molecules and functional materials.

In recent years, the demand for cyclopropyl-containing compounds like 1-cyclopropylpropan-1-amine has surged, driven by trends in drug discovery and sustainable chemistry. A 2023 study highlighted cyclopropylamines as key intermediates in designing kinase inhibitors and antiviral agents, aligning with global interest in targeted therapies. Additionally, the compound's potential in green chemistry applications—such as catalysts for CO2 capture—has sparked discussions in academic forums and patent filings. Its low environmental persistence compared to bulkier amines further positions it as a candidate for eco-friendly industrial processes.

Synthetic routes to CAS No. 219736-10-4 often involve reductive amination of cyclopropyl ketones or ring-opening strategies, with yields optimized via modern techniques like flow chemistry. Analytical methods such as GC-MS and NMR spectroscopy confirm its high purity (>98%), a critical parameter for regulatory compliance in pharmaceuticals. Notably, the compound's boiling point (estimated 150–160°C) and logP value (~1.2) make it suitable for formulations requiring moderate hydrophobicity, a feature frequently queried in chemical databases.

From an SEO perspective, users frequently search for "1-cyclopropylpropan-1-amine suppliers," "CAS 219736-10-4 safety data," or "cyclopropylamine derivatives in drug design," reflecting commercial and research priorities. Addressing these queries, this compound's handling guidelines recommend inert atmosphere storage to prevent oxidation, while its compatibility with common solvents (e.g., ethanol, DCM) is documented in technical literature. Emerging applications in battery electrolytes and polyurethane catalysts further expand its market relevance, as noted in recent investor reports.

In conclusion, 1-cyclopropylpropan-1-amine exemplifies the intersection of structural innovation and practical utility. Its role in advancing precision medicine and sustainable industrial chemistry ensures continued academic and commercial interest. Future research may explore its enantioselective synthesis or hybrid materials, topics gaining traction in peer-reviewed journals and grant proposals.

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