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• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues Amino acids and derivatives

Introduction to Methyl (1S,2S)-2-Aminocyclohexanecarboxylate (CAS No. 217799-18-3)

Methyl (1S,2S)-2-aminocyclohexanecarboxylate, with the CAS registry number 217799-18-3, is a versatile compound that has garnered significant attention in various fields of chemistry and pharmacology. This compound is a derivative of cyclohexane carboxylic acid, modified with a methyl ester group and an amino substituent. Its unique stereochemistry, characterized by the (1S,2S) configuration, plays a crucial role in its biological activity and chemical reactivity. Recent studies have highlighted its potential applications in drug development, particularly as a precursor for bioactive molecules.

The synthesis of methyl (1S,2S)-2-aminocyclohexanecarboxylate involves a series of well-defined chemical reactions, including esterification and stereoselective amino group introduction. Researchers have optimized these processes to achieve high yields and purity levels, ensuring its suitability for large-scale production. The compound's stability under various conditions has been thoroughly investigated, making it a reliable component in pharmaceutical formulations and industrial applications.

One of the most promising areas of research involving methyl (1S,2S)-2-aminocyclohexanecarboxylate is its role in peptide synthesis. Its amino group serves as an excellent nucleophile in amide bond formation, enabling the construction of complex peptide structures with high efficiency. Recent advancements in solid-phase peptide synthesis have further enhanced its utility in this domain.

In addition to its role in peptide synthesis, methyl (1S,2S)-2-aminocyclohexanecarboxylate has been explored for its potential in drug delivery systems. Its ability to form stable complexes with various drugs has been leveraged to improve bioavailability and reduce side effects. Studies published in the last year have demonstrated its effectiveness as a carrier for hydrophobic drugs, particularly in cancer therapy.

The stereochemistry of methyl (1S,2S)-2-aminocyclohexanecarboxylate is not only critical for its biological activity but also influences its physical properties. The compound exhibits distinct solubility profiles depending on the solvent used, which is an essential consideration for its application in different chemical processes. Researchers have employed advanced spectroscopic techniques to elucidate its molecular structure and confirm its stereochemical integrity.

Recent breakthroughs in computational chemistry have provided deeper insights into the electronic structure and reactivity of methyl (1S,2S)-2-aminocyclohexanecarboxylate. Quantum mechanical calculations have revealed that the amino group's lone pairs significantly contribute to the compound's nucleophilic character, making it an ideal candidate for various nucleophilic substitution reactions.

In conclusion, methyl (1S,2S)-2-aminocyclohexanecarboxylate (CAS No. 217799-18-3) stands out as a multifaceted compound with diverse applications across chemistry and pharmacology. Its unique stereochemistry and reactive functional groups make it an invaluable tool in modern drug discovery and chemical synthesis. As research continues to uncover new potential uses for this compound, it is poised to play an increasingly important role in advancing scientific and industrial endeavors.

• 267230-45-5(methyl (1R,2R)-2-aminocyclohexane-1-carboxylate)
• 107313-18-8(Cyclohexanecarboxylic acid, 2-amino-, methyl ester, trans-(±)-)
• 679789-29-8(Cyclohexanecarboxylic acid, 2-amino-, methyl ester, (1S,2R)-, acetate)
• 1630906-99-8(methyl trans-3-aminobicyclo[2.2.2]octane-2-carboxylate;hydrochloride)
• 760126-25-8(methyl 2-aminoadamantane-1-carboxylate)
• 503167-50-8(methyl (1S,2R)-2-aminocyclohexane-1-carboxylate)
• 40015-88-1(methyl 2-aminocyclohexanecarboxylate)
• 161618-52-6(rac-methyl (1R,2S)-2-aminocyclohexane-1-carboxylate)
• 107313-12-2(Cyclohexanecarboxylic acid, 2-amino-, methyl ester, cis-(±)-)
• 161618-50-4(Methyl trans-2-Aminocyclohexanecarboxylate)