Cas no 216659-47-1 (tert-Butyl 3-(dimethylamino)propylcarbamate)

Technical Introduction: tert-Butyl 3-(dimethylamino)propylcarbamate is a protected amine derivative featuring a tert-butoxycarbonyl (Boc) group and a dimethylamino-propyl moiety. This compound is valuable in organic synthesis, particularly as an intermediate in the preparation of pharmaceuticals and specialty chemicals. The Boc group offers selective deprotection under mild acidic conditions, enabling controlled functionalization. The dimethylamino-propyl side chain enhances solubility and reactivity in nucleophilic or catalytic processes. Its stability under basic conditions and compatibility with a range of reagents make it a versatile building block for constructing complex molecular architectures. The compound is typically handled under inert conditions to preserve its integrity.
tert-Butyl 3-(dimethylamino)propylcarbamate structure
216659-47-1 structure
Product Name:tert-Butyl 3-(dimethylamino)propylcarbamate
CAS No:216659-47-1
MF:C10H22N2O2
MW:202.293882846832
MDL:MFCD09955640
CID:243322
PubChem ID:45074599
Update Time:2025-06-26

tert-Butyl 3-(dimethylamino)propylcarbamate Chemical and Physical Properties

Names and Identifiers

    • tert-Butyl 3-(dimethylamino)propylcarbamate
    • Carbamic acid,N-[3-(dimethylamino)propyl]-, 1,1-dimethylethyl ester
    • tert-butyl N-[3-(dimethylamino)propyl]carbamate
    • AmbkkkkK578
    • Carbamic acid,[3-(dimethylamino)propyl]-,1,1-dimethylethyl ester(9ci)
    • SY277133
    • FT-0725276
    • 216659-47-1
    • SCHEMBL285008
    • CARBAMIC ACID, [3-(DIMETHYLAMINO)PROPYL]-, 1,1-DIMETHYLETHYL ESTER (9CI)
    • MFCD09955640
    • tert-Butyl [3-(dimethylamino)propyl]carbamate
    • DTXSID20662947
    • Tert-Butyl3-(dimethylamino)propylcarbamate
    • AKOS013789610
    • DB-066587
    • MDL: MFCD09955640
    • Inchi: 1S/C10H22N2O2/c1-10(2,3)14-9(13)11-7-6-8-12(4)5/h6-8H2,1-5H3,(H,11,13)
    • InChI Key: GWQBFGSYKVYBTO-UHFFFAOYSA-N
    • SMILES: O(C(NCCCN(C)C)=O)C(C)(C)C

Computed Properties

  • Exact Mass: 202.16800
  • Monoisotopic Mass: 202.168
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 14
  • Rotatable Bond Count: 6
  • Complexity: 174
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 41.6A^2
  • XLogP3: 1.3

Experimental Properties

  • Boiling Point: 287.882°C at 760 mmHg
  • Flash Point: 127.906°C
  • PSA: 41.57000
  • LogP: 1.85370

tert-Butyl 3-(dimethylamino)propylcarbamate Customs Data

  • HS CODE:2924199090
  • Customs Data:

    China Customs Code:

    2924199090

    Overview:

    2924199090. Other acyclic amides(Including acyclic carbamates)(Including its derivatives and salts). VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to, packing

    Summary:

    2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

tert-Butyl 3-(dimethylamino)propylcarbamate Pricemore >>

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Additional information on tert-Butyl 3-(dimethylamino)propylcarbamate

Comprehensive Overview of tert-Butyl 3-(dimethylamino)propylcarbamate (CAS No. 216659-47-1)

tert-Butyl 3-(dimethylamino)propylcarbamate (CAS No. 216659-47-1) is a specialized organic compound widely utilized in pharmaceutical and chemical synthesis. Its unique structure, featuring a tert-butyl group and a dimethylamino moiety, makes it a valuable intermediate in the development of bioactive molecules. Researchers and industries increasingly focus on this compound due to its versatility in drug discovery and peptide synthesis, aligning with the growing demand for high-purity intermediates in modern laboratories.

The compound’s molecular formula, C10H22N2O2, highlights its stability and compatibility with various organic reactions. A key advantage of tert-Butyl 3-(dimethylamino)propylcarbamate is its role as a protecting group for amines, a feature highly sought after in medicinal chemistry. Recent trends in AI-driven drug design and green chemistry have further amplified interest in such compounds, as they enable efficient and sustainable synthetic routes.

In the context of user-searched queries, common questions include: "What are the applications of tert-Butyl 3-(dimethylamino)propylcarbamate in pharmaceuticals?" or "How does CAS No. 216659-47-1 compare to other carbamate derivatives?" Addressing these, the compound’s primary use lies in API synthesis, where it facilitates the controlled release of active ingredients. Its low toxicity profile and compatibility with scalable production methods make it a preferred choice for industrial applications.

From a synthetic chemistry perspective, the compound’s reactivity is often explored in nucleophilic substitution and catalyzed coupling reactions. Laboratories prioritize its use due to its high yield and minimal byproducts, critical factors in cost-effective manufacturing. Additionally, its stability under ambient conditions ensures ease of handling and storage, reducing logistical challenges.

Emerging discussions in scientific forums also highlight its potential in bioconjugation techniques, particularly for labeling biomolecules. This aligns with the rising demand for diagnostic reagents and targeted therapies. As personalized medicine gains traction, intermediates like tert-Butyl 3-(dimethylamino)propylcarbamate are pivotal in developing tailored treatments.

For SEO optimization, this content integrates keywords such as "carbamate derivatives," "amine protection," and "pharmaceutical intermediates," which are frequently searched in academic and industrial circles. The compound’s relevance to cutting-edge research ensures its continued prominence in chemical databases and patent literature.

In summary, tert-Butyl 3-(dimethylamino)propylcarbamate (CAS No. 216659-47-1) represents a critical building block in modern chemistry, bridging gaps between synthetic efficiency and application diversity. Its adaptability to innovative methodologies positions it as a staple in both academic and industrial settings, driving advancements in life sciences and material engineering.

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