Cas no 2151616-83-8 (4-(1-ethylcyclobutyl)butan-1-amine)

4-(1-Ethylcyclobutyl)butan-1-amine is a specialized aliphatic amine featuring a cyclobutyl substituent, which imparts unique steric and electronic properties to the molecule. Its structure, combining a flexible butylamine chain with a constrained cyclobutyl ring, makes it a valuable intermediate in organic synthesis and pharmaceutical applications. The ethyl group at the 1-position of the cyclobutyl ring enhances lipophilicity, potentially improving bioavailability in drug design. This compound is particularly useful in the development of novel bioactive molecules, where its rigid yet tunable framework can influence binding affinity and metabolic stability. High purity and well-defined reactivity further support its utility in research and industrial processes.
4-(1-ethylcyclobutyl)butan-1-amine structure
2151616-83-8 structure
Product Name:4-(1-ethylcyclobutyl)butan-1-amine
CAS No:2151616-83-8
MF:C10H21N
MW:155.28044295311
CID:5909496
PubChem ID:165852765
Update Time:2025-05-21

4-(1-ethylcyclobutyl)butan-1-amine Chemical and Physical Properties

Names and Identifiers

    • 4-(1-ethylcyclobutyl)butan-1-amine
    • 2151616-83-8
    • EN300-1775341
    • Inchi: 1S/C10H21N/c1-2-10(7-5-8-10)6-3-4-9-11/h2-9,11H2,1H3
    • InChI Key: LRDKNACTRHAAAL-UHFFFAOYSA-N
    • SMILES: NCCCCC1(CC)CCC1

Computed Properties

  • Exact Mass: 155.167399674g/mol
  • Monoisotopic Mass: 155.167399674g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 5
  • Complexity: 105
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3.1
  • Topological Polar Surface Area: 26?2

4-(1-ethylcyclobutyl)butan-1-amine Pricemore >>

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Additional information on 4-(1-ethylcyclobutyl)butan-1-amine

4-(1-Ethylcyclobutyl)butan-1-amine (CAS No. 2151616-83-8): Properties, Applications, and Market Insights

4-(1-Ethylcyclobutyl)butan-1-amine (CAS No. 2151616-83-8) is a specialized organic compound that has garnered significant attention in the fields of pharmaceutical research and specialty chemicals. This unique amine derivative, characterized by its cyclobutyl and ethyl functional groups, offers a versatile scaffold for synthetic applications. Its molecular structure, C10H21N, provides a balance of lipophilicity and reactivity, making it a valuable intermediate in drug discovery and material science.

The compound's chemical properties include a molecular weight of 155.28 g/mol and a distinctive amine functionality that enables diverse chemical transformations. Researchers have explored its potential as a building block for bioactive molecules, particularly in the development of central nervous system (CNS) therapeutics. The ethylcyclobutyl moiety contributes to enhanced metabolic stability, a feature highly sought after in modern medicinal chemistry.

In recent years, 4-(1-ethylcyclobutyl)butan-1-amine has emerged as a subject of interest in AI-driven drug discovery platforms. Computational chemists frequently search for "novel amine scaffolds for drug design" or "cyclobutyl-containing building blocks," reflecting the growing demand for structurally diverse compounds in pharmaceutical R&D. The compound's unique spatial configuration makes it particularly valuable for addressing challenging biological targets, including G-protein-coupled receptors (GPCRs) and ion channels.

The synthesis of 2151616-83-8 typically involves multi-step organic transformations, with key steps including cyclobutane ring formation and subsequent amine functionalization. Process chemists have optimized routes to achieve high yields while maintaining excellent purity profiles, as evidenced by analytical data showing ≥98% purity in commercial samples. These advancements align with industry searches for "high-purity specialty amines" and "scalable synthetic routes for complex amines."

Market analysis reveals increasing demand for 4-(1-ethylcyclobutyl)butan-1-amine across several regions, particularly in North America and Asia-Pacific research hubs. Pharmaceutical companies frequently inquire about "custom synthesis of advanced amine intermediates" and "structure-activity relationship studies with cyclobutyl derivatives." The compound's price point reflects its specialized nature, typically commanding premium pricing in the fine chemicals market.

From an applications perspective, 2151616-83-8 has shown promise in multiple domains beyond pharmaceuticals. Materials scientists have investigated its potential as a monomer for specialty polymers, while agrochemical researchers explore its utility in crop protection agent development. These diverse applications contribute to its growing popularity in scientific literature and patent filings.

Quality control for 4-(1-ethylcyclobutyl)butan-1-amine follows stringent protocols, with characterization typically including NMR spectroscopy, mass spectrometry, and HPLC analysis. These analytical techniques address common researcher queries about "amine compound characterization methods" and "purity verification for building blocks." The compound's stability profile allows for standard storage conditions, typically at 2-8°C under inert atmosphere.

Recent scientific publications have highlighted innovative uses of cyclobutyl-containing amines in photopharmacology and targeted drug delivery systems. These cutting-edge applications align with trending searches for "next-generation drug delivery technologies" and "light-responsive pharmaceutical agents." The compound's structural features make it particularly suitable for these emerging fields.

From a regulatory standpoint, 4-(1-ethylcyclobutyl)butan-1-amine is not currently classified under restricted substance lists, making it accessible for research purposes worldwide. However, proper laboratory safety protocols should always be followed when handling any chemical substance, in line with institutional guidelines and good research practices.

The future outlook for 2151616-83-8 appears promising, with market analysts predicting steady growth in demand. This projection reflects broader trends in the specialty chemicals sector, where structurally unique intermediates continue to gain importance in advanced research applications. The compound's versatility ensures its relevance across multiple scientific disciplines for years to come.

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