• 1. Dissociative dynamics of O2 on Ag(110)?
  Ivor Lon?ari? Phys. Chem. Chem. Phys., 2015,17, 9436-9445
• 2. Fc microparticles can modulate the physical extent and magnitude of complement activity?
  David White,Sean R. Stowell Biomater. Sci., 2017,5, 463-474
• 3. Estimates of hydride ion stability in condensed systems: energy of formation and solvation in aqueous and polar-organic solvents
  Craig A. Kelly,David R. Rosseinsky Phys. Chem. Chem. Phys., 2001,3, 2086-2090
• 4. Evolution in surface coverage of CH3NH3PbI3?XClXvia heat assisted solvent vapour treatment and their effects on photovoltaic performance of devices
  Dhirendra K. Chaudhary,Pramendra Kumar,Lokendra Kumar RSC Adv., 2016,6, 94731-94738
• 5. Emergence of cationic polyamine dendrimersomes: design, stimuli sensitivity and potential biomedical applications
  Partha Laskar,Christine Dufès Nanoscale Adv., 2021,3, 6007-6026

4-Quinolinecarboxylic Acid, 7-Iodo-

4-Quinolinecarboxylic acid, 7-iodo- (CAS No. 2138307-26-1) is a highly specialized organic compound that has garnered significant attention in the fields of organic chemistry, pharmacology, and materials science. This compound belongs to the quinoline family, a class of heterocyclic aromatic compounds that are widely studied for their diverse applications in drug discovery and advanced materials. The presence of the iodo group at the 7-position and the carboxylic acid group at the 4-position introduces unique electronic and structural properties, making this compound a valuable building block in modern chemical research.

The synthesis of 4-Quinolinecarboxylic acid, 7-iodo- typically involves multi-step processes that require precise control over reaction conditions. Recent advancements in catalytic methods and transition metal-mediated coupling reactions have enabled more efficient and scalable syntheses of this compound. For instance, researchers have employed palladium-catalyzed cross-coupling reactions to introduce the iodo group at the 7-position with high regioselectivity. These methods not only enhance the purity of the final product but also reduce the environmental footprint of the synthesis process.

In terms of applications, 4-Quinolinecarboxylic acid, 7-iodo- has been extensively studied for its potential in drug design. The quinoline backbone is known for its ability to interact with various biological targets, such as protein kinases and G-protein coupled receptors (GPCRs). The iodo group at the 7-position can serve as a site for further functionalization, allowing chemists to explore diverse bioisosteres and analogs. Recent studies have demonstrated that this compound exhibits promising activity against certain cancer cell lines, particularly those resistant to conventional chemotherapy agents. Its ability to modulate key signaling pathways makes it a candidate for developing next-generation anticancer therapies.

Beyond pharmacology, 4-Quinolinecarboxylic acid, 7-iodo- has also found applications in materials science. The aromaticity and conjugation within the quinoline framework make it suitable for use in organic electronics. Researchers have incorporated this compound into thin-film transistor (TFT) devices, where it exhibits excellent charge transport properties. The carboxylic acid group provides additional functionality by enabling surface modification and compatibility with various substrates. These properties make it a potential candidate for use in flexible electronics and optoelectronic devices.

The structural versatility of 4-Quinolinecarboxylic acid, 7-iodo- has also led to its use in supramolecular chemistry. The iodo group can act as a coordinating unit in metallo-supramolecular assemblies, while the carboxylic acid group can participate in hydrogen bonding networks. Recent studies have shown that this compound can self-assemble into ordered nanostructures under specific conditions, which could have implications for drug delivery systems and nanotechnology.

In conclusion, 4-Quinolinecarboxylic acid, 7-iodo- (CAS No. 2138307-26-1) is a versatile compound with a wide range of applications across multiple disciplines. Its unique chemical structure and functional groups make it an invaluable tool for researchers in drug discovery, materials science, and supramolecular chemistry. As ongoing research continues to uncover new properties and applications of this compound, its role in advancing modern science is expected to grow significantly.

• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)