Cas no 21354-48-3 (Benzenamine, N,2,5-trimethyl-)

Benzenamine, N,2,5-trimethyl-, also known as 2,5-dimethyl-N-methylaniline, is a substituted aromatic amine with the molecular formula C9H13N. This compound is characterized by its methyl substituents at the 2, 5, and nitrogen positions, which influence its reactivity and physical properties. It serves as a versatile intermediate in organic synthesis, particularly in the production of dyes, pharmaceuticals, and agrochemicals. The methyl groups enhance its solubility in organic solvents and moderate its basicity, making it suitable for selective reactions. Its stable aromatic core and functionalized structure allow for further derivatization, offering utility in fine chemical manufacturing and research applications. Proper handling is advised due to potential toxicity and reactivity.
Benzenamine, N,2,5-trimethyl- structure
Benzenamine, N,2,5-trimethyl- structure
Product Name:Benzenamine, N,2,5-trimethyl-
CAS No:21354-48-3
MF:C9H13N
MW:135.206222295761
CID:1404608
PubChem ID:14918440
Update Time:2025-11-06

Benzenamine, N,2,5-trimethyl- Chemical and Physical Properties

Names and Identifiers

    • Benzenamine, N,2,5-trimethyl-
    • 2,5-dimethyl-N-methylaniline
    • N,2,5-Trimethylaniline
    • 21354-48-3
    • EN300-58414
    • AKOS000258486
    • F73587
    • SCHEMBL2092832
    • AB01003806-01
    • Inchi: 1S/C9H13N/c1-7-4-5-8(2)9(6-7)10-3/h4-6,10H,1-3H3
    • InChI Key: FLLXIDNFXBLBMT-UHFFFAOYSA-N
    • SMILES: N(C)C1C=C(C)C=CC=1C

Computed Properties

  • Exact Mass: 135.10489
  • Monoisotopic Mass: 135.104799419g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 1
  • Complexity: 101
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.3
  • Topological Polar Surface Area: 12?2

Experimental Properties

  • PSA: 12.03

Benzenamine, N,2,5-trimethyl- Pricemore >>

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Benzenamine, N,2,5-trimethyl- Related Literature

Additional information on Benzenamine, N,2,5-trimethyl-

Recent Advances in the Study of Benzenamine, N,2,5-trimethyl- (CAS: 21354-48-3) in Chemical Biology and Pharmaceutical Research

Benzenamine, N,2,5-trimethyl- (CAS: 21354-48-3) is a chemical compound of significant interest in the fields of chemical biology and pharmaceutical research. Recent studies have explored its potential applications in drug development, particularly due to its unique structural properties and reactivity. This research brief aims to summarize the latest findings related to this compound, focusing on its synthesis, biological activity, and potential therapeutic uses.

One of the key areas of investigation has been the synthesis and modification of Benzenamine, N,2,5-trimethyl-. Researchers have developed novel synthetic routes to improve yield and purity, which are critical for its application in pharmaceutical formulations. Advanced techniques such as microwave-assisted synthesis and catalytic hydrogenation have been employed to optimize the production process, resulting in higher efficiency and reduced environmental impact.

In terms of biological activity, recent studies have highlighted the compound's potential as a precursor for the development of new antimicrobial agents. Laboratory tests have demonstrated its efficacy against a range of bacterial strains, including antibiotic-resistant pathogens. These findings suggest that Benzenamine, N,2,5-trimethyl- could play a crucial role in addressing the growing challenge of antimicrobial resistance.

Additionally, the compound has shown promise in the field of oncology. Preliminary studies indicate that derivatives of Benzenamine, N,2,5-trimethyl- exhibit cytotoxic effects on certain cancer cell lines, particularly those associated with solid tumors. Researchers are currently investigating the mechanisms underlying these effects, with a focus on apoptosis induction and cell cycle disruption.

Another noteworthy aspect of recent research is the exploration of the compound's pharmacokinetic properties. Studies have examined its absorption, distribution, metabolism, and excretion (ADME) profiles to assess its suitability as a drug candidate. Early results suggest favorable bioavailability and low toxicity, making it a viable candidate for further development.

Despite these promising findings, challenges remain in the clinical translation of Benzenamine, N,2,5-trimethyl-. Issues such as scalability of synthesis, stability under physiological conditions, and potential side effects need to be addressed. Ongoing research is focused on overcoming these hurdles through structural modifications and formulation improvements.

In conclusion, Benzenamine, N,2,5-trimethyl- (CAS: 21354-48-3) represents a compound of considerable interest in chemical biology and pharmaceutical research. Its diverse biological activities and potential therapeutic applications make it a focal point for ongoing studies. Future research directions may include the development of more potent derivatives, detailed mechanistic studies, and preclinical evaluations to further elucidate its therapeutic potential.

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