Cas no 212651-47-3 (2-((((9H-Fluoren-9-YL)methoxy)carbonyl)(methyl)amino)acetic acid hydrate)

2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)acetic acid hydrate is a fluorenylmethyloxycarbonyl (Fmoc)-protected amino acid derivative, commonly employed in solid-phase peptide synthesis (SPPS). Its key advantages include the Fmoc group's orthogonality to acid-labile protecting groups, enabling selective deprotection under mild basic conditions. The methyl-substituted amino backbone enhances steric control, improving peptide chain assembly efficiency. The hydrate form ensures stability during storage and handling. This compound is particularly valuable in the synthesis of modified peptides, where precise incorporation of N-methylated residues is required. Its compatibility with standard SPPS protocols makes it a reliable choice for researchers in peptide chemistry and pharmaceutical development.
2-((((9H-Fluoren-9-YL)methoxy)carbonyl)(methyl)amino)acetic acid hydrate structure
212651-47-3 structure
Product Name:2-((((9H-Fluoren-9-YL)methoxy)carbonyl)(methyl)amino)acetic acid hydrate
CAS No:212651-47-3
MF:C18H19NO5
MW:329.347165346146
MDL:MFCD00180724
CID:2084013
Update Time:2025-08-05

2-((((9H-Fluoren-9-YL)methoxy)carbonyl)(methyl)amino)acetic acid hydrate Chemical and Physical Properties

Names and Identifiers

    • Fmoc-sarcosine Hydrate
    • 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)acetic acid hydrate
    • Glycine, N-?[(9H-?fluoren-?9-?ylmethoxy)?carbonyl]?-?N-?methyl-?, monohydrate (9CI)
    • Fmoc-sarcosine monohydrate
    • 2-[9H-fluoren-9-ylmethoxycarbonyl(methyl)amino]acetic acid;hydrate
    • Fmoc-sarcosineHydrate
    • KSC915Q4D
    • 6986AH
    • TRA0078087
    • AM82640
    • SY030042
    • ST2413096
    • AX8215142
    • AB0065948
    • {[(9H-fluoren-9-ylmethox
    • 2-((((9H-Fluoren-9-YL)methoxy)carbonyl)(methyl)amino)acetic acid hydrate
    • MDL: MFCD00180724
    • Inchi: 1S/C18H17NO4.H2O/c1-19(10-17(20)21)18(22)23-11-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16;/h2-9,16H,10-11H2,1H3,(H,20,21);1H2
    • InChI Key: CUJSWOOWOONPRH-UHFFFAOYSA-N
    • SMILES: O(C(N(C)CC(=O)O)=O)CC1C2C=CC=CC=2C2C=CC=CC1=2.O

Computed Properties

  • Exact Mass: 329.12600
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 24
  • Rotatable Bond Count: 5
  • Complexity: 430
  • Topological Polar Surface Area: 67.8

Experimental Properties

  • Boiling Point: 512.8℃ at 760 mmHg
  • PSA: 76.07000
  • LogP: 2.88760

2-((((9H-Fluoren-9-YL)methoxy)carbonyl)(methyl)amino)acetic acid hydrate Pricemore >>

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