• 1. Fast synthesis of copper nanoclusters through the use of hydrogen peroxide additive and their application for the fluorescence detection of Hg2+ in water samples?
  Liao Xiaoqing,Li Ruiyi,Li Zaijun,Sun Xiulan,Wang Zhouping,Liu Junkang New J. Chem., 2015,39, 5240-5248
• 2. Fatty acid eutectic mixtures and derivatives from non-edible animal fat as phase change materials?
  Pau Gallart-Sirvent,Marc Martín,Gemma Villorbina,Mercè Balcells,Aran Solé,Luisa F. Cabeza,Ramon Canela-Garayoa RSC Adv., 2017,7, 24133-24139
• 3. Evolution of calcium phosphate precipitation in hanging drop vapor diffusion by in situRaman microspectroscopy
  Gloria Belén Ramírez-Rodríguez,José Manuel Delgado-López,Jaime Gómez-Morales CrystEngComm, 2013,15, 2206-2212
• 4. Empowering microfluidics by micro-3D printing and solution-based mineral coating?
  Hongxia Li,Aikifa Raza,Qiaoyu Ge,Jin-You Lu,TieJun Zhang Soft Matter, 2020,16, 6841-6849
• 5. Emerging 2D hybrid nanomaterials: towards enhanced sensitive and selective conductometric gas sensors at room temperature
  Hanie Hashtroudi,Ian D. R. Mackinnon J. Mater. Chem. C, 2020,8, 13108-13126

• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues Amino acids and derivatives

Professional Introduction to Ethyl 2-(1-ethoxyethylidene)aminoacetate (CAS No. 21164-33-0)

Ethyl 2-(1-ethoxyethylidene)aminoacetate, a compound with the chemical identifier CAS No. 21164-33-0, is a versatile intermediate in organic synthesis and has garnered significant attention in the field of pharmaceutical chemistry. This compound, characterized by its ethyl ester and aminoacetic acid derivatives, plays a crucial role in the development of novel therapeutic agents. Its unique structural properties make it an attractive candidate for further exploration in drug discovery and molecular biology research.

The molecular structure of ethyl 2-(1-ethoxyethylidene)aminoacetate consists of an ethoxyethylidene group attached to an aminoacetic acid backbone, which contributes to its reactivity and functional diversity. This architecture allows for facile modifications, enabling chemists to tailor its properties for specific applications. In recent years, the compound has been studied for its potential in synthesizing bioactive molecules, particularly those targeting neurological and metabolic disorders.

Recent advancements in synthetic chemistry have highlighted the utility of ethyl 2-(1-ethoxyethylidene)aminoacetate in constructing complex heterocyclic frameworks. These frameworks are often integral to the development of drugs that interact with biological targets with high specificity. For instance, researchers have utilized this compound to develop inhibitors of enzymes involved in inflammation and pain pathways. The ability to incorporate functional groups such as amine and ester moieties into the molecule enhances its compatibility with various pharmacophores, making it a valuable building block in medicinal chemistry.

In addition to its role in drug development, ethyl 2-(1-ethoxyethylidene)aminoacetate has been explored in the synthesis of agrochemicals and specialty chemicals. Its reactivity allows for the formation of stable intermediates that can be further functionalized to produce compounds with desired agronomic properties. This application underscores the compound's versatility beyond pharmaceuticals, contributing to advancements in sustainable agriculture.

The chemical properties of ethyl 2-(1-ethoxyethylidene)aminoacetate make it a suitable candidate for use in catalytic processes. Researchers have investigated its potential as a ligand or co-catalyst in various organic transformations, including cross-coupling reactions and hydrogenations. These studies aim to optimize reaction conditions and improve yields, which are critical factors in industrial-scale synthesis. The compound's ability to stabilize reactive intermediates and facilitate bond formations has opened new avenues for efficient synthetic methodologies.

From a biological perspective, ethyl 2-(1-ethoxyethylidene)aminoacetate has been studied for its potential bioactivity. Preliminary studies suggest that derivatives of this compound may exhibit properties such as antioxidant and anti-inflammatory effects. These findings are particularly intriguing given the increasing interest in natural product-inspired drug design. By leveraging the structural motifs found in ethyl 2-(1-ethoxyethylidene)aminoacetate, scientists aim to develop novel therapeutics that mimic the bioactive principles of plants and microorganisms.

The synthesis of ethyl 2-(1-ethoxyethylidene)aminoacetate involves multi-step organic reactions that highlight the ingenuity of modern synthetic strategies. Techniques such as Grignard reactions, aldol condensations, and esterifications are commonly employed to construct the desired molecular framework. The optimization of these reactions is essential for achieving high purity and yield, which are paramount for industrial applications. Advances in green chemistry have also influenced the synthesis process, promoting solvent-free reactions and catalytic methods that minimize environmental impact.

Future research directions for ethyl 2-(1-ethoxyethylidene)aminoacetate include exploring its role in drug delivery systems. The compound's ability to form stable complexes with other molecules makes it a promising candidate for encapsulating therapeutic agents. Such systems can enhance drug solubility, improve bioavailability, and target specific tissues or cells. These developments could revolutionize how drugs are administered and could lead to more effective treatments for a wide range of diseases.

In conclusion, ethyl 2-(1-ethoxyethylidene)aminoacetate (CAS No. 21164-33-0) is a multifaceted compound with significant potential in pharmaceuticals, agrochemicals, and catalysis. Its unique structural features enable diverse applications, making it a cornerstone of modern chemical research. As scientists continue to uncover new uses for this compound, its importance is likely to grow further, driving innovation across multiple scientific disciplines.

• 24474-93-9(2-methyl-4H-oxazol-5-one)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)