• 1. Distinction of trans–cis photoisomers with comparable optical properties in multiple-state photochromic systems – examining a molecule with three azobenzenes via in situ irradiation NMR spectroscopy?
  Jonas Kind,Lukas Kaltschnee,Martin Leyendecker,Christina M. Thiele Chem. Commun., 2016,52, 12506-12509
• 2. Excimer emission and magnetoluminescence of radical-based zinc(ii) complexes doped in host crystals?
  Shojiro Kimura,Tetsuro Kusamoto Chem. Commun., 2020,56, 11195-11198
• 3. Fate of nitrogen-15 in the subsequent growing season of greenhouse tomato plants (Lycopersicon esculentum Mill) as influenced by alternate partial root-zone irrigation
  Maomao Hou,Fenglin Zhong,Qiu Jin,Enjiang Liu,Jie Feng,Tengyun Wang,Yue Gao RSC Adv., 2017,7, 34392-34400
• 4. Emerging investigators
  Polym. Chem., 2015,6, 5501-5502
• 5. Excellent lithium ion storage property of porous MnCo2O4 nanorods?
  Peiyuan Zeng,Xiaoxiao Wang,Ming Ye,Qiuyang Ma,Jianwen Li,Wanwan Wang,Baoyou Geng,Zhen Fang RSC Adv., 2016,6, 23074-23084

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridopyrimidines Pyridopyrimidines
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridopyrimidines

Comprehensive Analysis of 2-methyl-5,6,7,8-tetrahydro-pyrido4,3-dpyrimidine hydrochloride (CAS No. 210538-73-1)

The compound 2-methyl-5,6,7,8-tetrahydro-pyrido4,3-dpyrimidine hydrochloride (CAS No. 210538-73-1) is a significant heterocyclic molecule with a wide range of potential applications in pharmaceutical and chemical research. This pyridopyrimidine derivative has garnered attention due to its unique structural features, which make it a valuable scaffold for drug discovery and development. Researchers are particularly interested in its bioactive properties, as it shares structural similarities with other pharmacologically active compounds.

In recent years, the demand for heterocyclic compounds like 2-methyl-5,6,7,8-tetrahydro-pyrido4,3-dpyrimidine hydrochloride has surged, driven by advancements in medicinal chemistry and drug design. The compound's CAS No. 210538-73-1 is frequently searched in scientific databases, reflecting its relevance in academic and industrial research. Its hydrochloride salt form enhances solubility, making it more suitable for in vitro and in vivo studies.

One of the key trends in modern chemistry is the exploration of small molecule inhibitors and kinase modulators, where 2-methyl-5,6,7,8-tetrahydro-pyrido4,3-dpyrimidine hydrochloride shows promise. Its pyrimidine core is a common motif in FDA-approved drugs, particularly those targeting central nervous system (CNS) disorders and metabolic diseases. This aligns with the growing interest in neuroprotective agents and anti-inflammatory compounds, which are hot topics in biomedical research.

The synthesis of 2-methyl-5,6,7,8-tetrahydro-pyrido4,3-dpyrimidine hydrochloride involves sophisticated organic synthesis techniques, including cyclization reactions and catalytic hydrogenation. Researchers often optimize these methods to improve yield and purity, as highlighted in recent peer-reviewed journals. The compound's molecular weight and physicochemical properties are also critical for its application in high-throughput screening (HTS) platforms.

Another area of interest is the compound's potential role in cancer research. Given the rise in precision medicine and targeted therapies, 2-methyl-5,6,7,8-tetrahydro-pyrido4,3-dpyrimidine hydrochloride is being evaluated for its anti-proliferative effects. Its mechanism of action may involve enzyme inhibition or receptor modulation, making it a candidate for further preclinical studies.

From a commercial perspective, the availability of 2-methyl-5,6,7,8-tetrahydro-pyrido4,3-dpyrimidine hydrochloride is crucial for contract research organizations (CROs) and pharmaceutical companies. Suppliers often list it under CAS No. 210538-73-1 with detailed specification sheets, ensuring compliance with Good Manufacturing Practices (GMP). This transparency is vital for researchers seeking high-purity compounds for their experiments.

In conclusion, 2-methyl-5,6,7,8-tetrahydro-pyrido4,3-dpyrimidine hydrochloride (CAS No. 210538-73-1) represents a versatile and promising compound in modern scientific research. Its applications span drug discovery, cancer therapy, and neuroprotection, aligning with current trends in biomedicine. As the scientific community continues to explore its potential, this compound is likely to remain a focal point in innovative therapeutic development.

• 157327-49-6(5H,6H,7H,8H-pyrido[4,3-d]pyrimidine dihydrochloride)
• 880361-75-1(2-Cyclopropyl-5,6,7,8-tetrahydro-pyrido4,3-dpyrimidine)
• 66521-83-3(6-methyl-5,6,7,8-tetrahydropyrido4,3-dpyrimidine)
• 300552-48-1(2-Phenyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine hydrochloride)
• 944901-77-3(4-methyl-5H,6H,7H,8H-pyrido4,3-dpyrimidine)
• 1187830-73-4(4-methyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine;hydrochloride)
• 1211516-37-8(2-tert-Butyl-5,6,7,8-tetrahydropyrido4,3-dpyrimidine)
• 424819-91-0(2-Methyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine;dihydrochloride)
• 192869-50-4(5H,6H,7H,8H-pyrido[4,3-d]pyrimidine)
• 210538-68-4(5,6,7,8-Tetrahydropyrido4,3-dpyrimidine Hydrochloride)