Cas no 208643-03-2 (2-(Morpholinosulfonyl)aniline)

2-(Morpholinosulfonyl)aniline is a specialized organic compound featuring both a morpholine sulfonyl group and an aniline moiety. This structure imparts unique reactivity, making it valuable as an intermediate in pharmaceutical and agrochemical synthesis. The morpholinosulfonyl group enhances solubility and stability, while the aniline functionality allows for further derivatization, such as diazotization or coupling reactions. Its well-defined chemical properties ensure consistent performance in complex synthetic pathways. The compound is particularly useful in the development of sulfonamide-based active ingredients, where precise functional group compatibility is critical. High purity grades are available to meet stringent research and industrial requirements.
2-(Morpholinosulfonyl)aniline structure
2-(Morpholinosulfonyl)aniline structure
Product Name:2-(Morpholinosulfonyl)aniline
CAS No:208643-03-2
MF:C10H14N2O3S
MW:242.294761180878
MDL:MFCD04035364
CID:1081256
PubChem ID:1132819
Update Time:2025-06-13

2-(Morpholinosulfonyl)aniline Chemical and Physical Properties

Names and Identifiers

    • 2-(Morpholinosulfonyl)aniline
    • 2-(4-morpholinylsulfonyl)Benzenamine
    • 2-morpholin-4-ylsulfonylaniline
    • 2-(morpholin-4-ylsulfonyl)aniline
    • 4-[(2-Aminophenyl)sulfonyl]morpholine
    • DB-066356
    • EN300-30491
    • 208643-03-2
    • AKOS000145698
    • J-514191
    • 2-(morpholinylsulfonyl)aniline
    • 2-(morpholine-4-sulfonyl)aniline
    • 2-(Morpholine-4-sulfonyl)-phenylamine
    • NCGC00181896-01
    • Z278051996
    • SCHEMBL2062548
    • MFCD04035364
    • DTXSID20360618
    • Benzenamine, 2-(4-morpholinylsulfonyl)-
    • WLPZGLWVUUJJTB-UHFFFAOYSA-N
    • J-013686
    • MDL: MFCD04035364
    • Inchi: 1S/C10H14N2O3S/c11-9-3-1-2-4-10(9)16(13,14)12-5-7-15-8-6-12/h1-4H,5-8,11H2
    • InChI Key: WLPZGLWVUUJJTB-UHFFFAOYSA-N
    • SMILES: S(C1C=CC=CC=1N)(N1CCOCC1)(=O)=O

Computed Properties

  • Exact Mass: 242.07300
  • Monoisotopic Mass: 242.072513g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 16
  • Rotatable Bond Count: 2
  • Complexity: 319
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • XLogP3: 0.6
  • Topological Polar Surface Area: 81?2

Experimental Properties

  • PSA: 81.01000
  • LogP: 1.88960

2-(Morpholinosulfonyl)aniline Customs Data

  • HS CODE:2935009090
  • Customs Data:

    China Customs Code:

    2935009090

    Overview:

    2935009090 Other sulphonates(Acyl)amine. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:6.5% general tariff:35.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

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2-(Morpholinosulfonyl)aniline Suppliers

Amadis Chemical Company Limited
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(CAS:208643-03-2)2-(Morpholinosulfonyl)aniline
Order Number:A1139938
Stock Status:in Stock
Quantity:5g/25g
Purity:99%
Pricing Information Last Updated:Thursday, 29 August 2024 22:49
Price ($):267.0/710.0

Additional information on 2-(Morpholinosulfonyl)aniline

Professional Introduction to 2-(Morpholinosulfonyl)aniline (CAS No: 208643-03-2)

2-(Morpholinosulfonyl)aniline, identified by the CAS number 208643-03-2, is a significant compound in the field of chemical and pharmaceutical research. This compound belongs to a class of derivatives that exhibit unique structural and functional properties, making it a valuable subject of study in medicinal chemistry and drug development. The morpholino sulfonyl group in its molecular structure imparts specific chemical reactivity and stability, which are crucial for its potential applications in synthetic chemistry and biological assays.

The synthesis of 2-(Morpholinosulfonyl)aniline involves a series of well-defined chemical reactions that highlight the compound's versatility. The process typically begins with the reaction of aniline derivatives with sulfonylating agents, followed by the introduction of the morpholine moiety through nucleophilic substitution or other coupling reactions. The precise control of reaction conditions is essential to achieve high yields and purity, ensuring that the final product meets the stringent requirements of pharmaceutical applications.

In recent years, 2-(Morpholinosulfonyl)aniline has garnered attention for its potential role in the development of novel therapeutic agents. Its structural features make it a promising candidate for inhibiting various enzymatic targets, which are implicated in diseases such as cancer, inflammation, and neurological disorders. For instance, studies have demonstrated that derivatives of this compound can interact with specific protein kinases, modulating their activity and potentially leading to new treatment strategies.

One of the most compelling aspects of 2-(Morpholinosulfonyl)aniline is its ability to serve as a scaffold for drug design. Researchers have leveraged its unique chemical properties to develop libraries of compounds with enhanced binding affinity and selectivity. These efforts have led to the identification of several lead candidates that are currently undergoing further investigation in preclinical studies. The morpholino sulfonyl group, in particular, has been found to improve solubility and metabolic stability, which are critical factors for drug efficacy and safety.

The latest advancements in computational chemistry have also played a pivotal role in understanding the behavior of 2-(Morpholinosulfonyl)aniline. Molecular modeling techniques have allowed researchers to predict how this compound interacts with biological targets at an atomic level. These insights have not only accelerated the drug discovery process but also provided a deeper understanding of its mechanism of action. Such computational approaches are increasingly integral to modern pharmaceutical research, enabling more efficient and targeted development of new drugs.

Moreover, the environmental impact of synthesizing 2-(Morpholinosulfonyl)aniline has been a focus of recent studies. Efforts have been made to optimize synthetic routes to minimize waste and reduce energy consumption. Green chemistry principles have been applied to develop more sustainable methods for producing this compound, aligning with global initiatives to promote environmentally friendly practices in the chemical industry. These innovations highlight the compound's potential not only as a therapeutic agent but also as a model for sustainable chemical synthesis.

The future prospects for 2-(Morpholinosulfonyl)aniline are promising, with ongoing research exploring its applications in various fields. Its versatility as a building block for drug design continues to drive innovation, and new derivatives are being synthesized with improved pharmacological properties. As our understanding of biological systems grows, so too does the potential for this compound to contribute to groundbreaking therapies that address unmet medical needs.

In conclusion, 2-(Morpholinosulfonyl)aniline (CAS No: 208643-03-2) represents a significant advancement in chemical and pharmaceutical research. Its unique structural features and functional properties make it a valuable tool for developing novel therapeutic agents. With continued research and innovation, this compound is poised to play a crucial role in addressing some of the most pressing challenges in medicine today.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:208643-03-2)2-(Morpholinosulfonyl)aniline
A1139938
Purity:99%/99%
Quantity:5g/25g
Price ($):267.0/710.0
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