Cas no 20854-60-8 ([1,1'-Biphenyl]-4-methanol,4'-methoxy-)

[1,1'-Biphenyl]-4-methanol,4'-methoxy- is a biphenyl derivative featuring a hydroxymethyl group at the 4-position and a methoxy substituent at the 4'-position. This compound serves as a versatile intermediate in organic synthesis, particularly in the preparation of liquid crystals, pharmaceuticals, and advanced materials. Its rigid biphenyl core enhances thermal and chemical stability, while the functional groups allow for further derivatization, enabling tailored modifications for specific applications. The methoxy group contributes to electron-donating properties, influencing reactivity in cross-coupling reactions. Suitable for research and industrial use, it offers high purity and consistent performance in synthetic workflows.
[1,1'-Biphenyl]-4-methanol,4'-methoxy- structure
20854-60-8 structure
Product Name:[1,1'-Biphenyl]-4-methanol,4'-methoxy-
CAS No:20854-60-8
MF:C14H14O2
MW:214.259764194489
MDL:MFCD01862509
CID:254036
PubChem ID:1051637
Update Time:2025-09-28

[1,1'-Biphenyl]-4-methanol,4'-methoxy- Chemical and Physical Properties

Names and Identifiers

    • [1,1'-Biphenyl]-4-methanol,4'-methoxy-
    • (4'-METHOXYBIPHENYL-4-YL)-METHANOL
    • [4-(4-methoxyphenyl)phenyl]methanol
    • (4'-methoxy[1,1'-biphenyl]-4-yl)methanol
    • 4-(4'-methoxyphenyl)benzylalcohol
    • 4-(4-Methoxy-phenyl)-benzylalkohol
    • 4'-Methoxy-[1,1'-biphenyl]-4-methanol
    • 4-Methoxy-4'-hydroxymethyl-biphenyl
    • 4'-methoxybiphenyl-4-carbinol
    • 20854-60-8
    • A50591
    • DTXSID30359992
    • AKOS002683031
    • Oprea1_606510
    • (4'-Methoxy-[1,1'-biphenyl]-4-yl)methanol
    • AN-278/13643016
    • CS-0196172
    • (4'-Methoxy-biphenyl-4-yl)-methanol
    • GVRSPKZCGUMKFK-UHFFFAOYSA-N
    • SCHEMBL6285826
    • [1,1'-Biphenyl]-4-methanol, 4'-methoxy-
    • BB 0224052
    • {4'-METHOXY-[1,1'-BIPHENYL]-4-YL}METHANOL
    • MFCD01862509
    • MDL: MFCD01862509
    • Inchi: 1S/C14H14O2/c1-16-14-8-6-13(7-9-14)12-4-2-11(10-15)3-5-12/h2-9,15H,10H2,1H3
    • InChI Key: GVRSPKZCGUMKFK-UHFFFAOYSA-N
    • SMILES: O(C)C1C=CC(=CC=1)C1C=CC(CO)=CC=1

Computed Properties

  • Exact Mass: 214.09900
  • Monoisotopic Mass: 214.099
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 16
  • Rotatable Bond Count: 3
  • Complexity: 189
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.7
  • Topological Polar Surface Area: 29.5A^2

Experimental Properties

  • Density: 1.112
  • Boiling Point: 376°C at 760 mmHg
  • Flash Point: 173.5°C
  • Refractive Index: 1.578
  • PSA: 29.46000
  • LogP: 2.85450

[1,1'-Biphenyl]-4-methanol,4'-methoxy- Customs Data

  • HS CODE:2922299090
  • Customs Data:

    China Customs Code:

    2922299090

    Overview:

    2922299090. Other amino groups(naphthol\phenol)And ether\Esters [including their salts, Except those containing more than one oxygen-containing group]. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to, The color of ethanolamine and its salt should be reported, The package of ethanolamine and its salt shall be declared

    Summary:

    2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

[1,1'-Biphenyl]-4-methanol,4'-methoxy- Pricemore >>

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Additional information on [1,1'-Biphenyl]-4-methanol,4'-methoxy-

Comprehensive Overview of [1,1'-Biphenyl]-4-methanol,4'-methoxy- (CAS No. 20854-60-8)

[1,1'-Biphenyl]-4-methanol,4'-methoxy- (CAS No. 20854-60-8) is a biphenyl derivative with significant applications in organic synthesis, pharmaceuticals, and material science. This compound, characterized by its methoxy and hydroxymethyl functional groups, exhibits unique chemical properties that make it valuable for researchers and industries. Its molecular structure, combining aromaticity and polar substituents, allows for versatile reactivity, enabling its use as an intermediate in the synthesis of more complex molecules.

The growing interest in biphenyl-based compounds stems from their role in developing advanced materials, such as liquid crystals and organic semiconductors. With the rise of sustainable chemistry, researchers are exploring eco-friendly synthesis routes for [1,1'-Biphenyl]-4-methanol,4'-methoxy-, aligning with the global push for greener alternatives. This compound's potential in drug discovery is also noteworthy, as biphenyl scaffolds are frequently employed in medicinal chemistry to enhance bioavailability and target specificity.

One of the most searched questions related to CAS No. 20854-60-8 is its solubility and stability under various conditions. Studies indicate that this compound is soluble in common organic solvents like ethanol, methanol, and dimethyl sulfoxide (DMSO), making it convenient for laboratory use. Its stability at room temperature further adds to its practicality. Additionally, its methoxy group contributes to electron-donating effects, which can influence the optical and electronic properties of derived materials.

In the context of pharmaceutical intermediates, [1,1'-Biphenyl]-4-methanol,4'-methoxy- has garnered attention for its potential role in synthesizing bioactive molecules. For instance, biphenyl derivatives are often explored for their anti-inflammatory and antioxidant properties. The compound's structural flexibility allows for modifications that can optimize pharmacokinetic profiles, a key consideration in modern drug design. Researchers are also investigating its utility in catalysis, where it may serve as a ligand or co-catalyst in asymmetric synthesis.

From an industrial perspective, the demand for high-purity biphenyl derivatives is increasing, driven by advancements in electronics and nanotechnology. [1,1'-Biphenyl]-4-methanol,4'-methoxy- is no exception, as its derivatives are being tested for use in organic light-emitting diodes (OLEDs) and photovoltaic cells. The compound's ability to form stable thin films and its tunable electronic properties make it a candidate for next-generation optoelectronic devices.

Environmental and safety considerations are also critical when working with CAS No. 20854-60-8. While it is not classified as hazardous under standard regulations, proper handling protocols should be followed to minimize exposure. The compound's biodegradability and environmental impact are areas of ongoing research, particularly as industries seek to align with stricter sustainability standards.

In summary, [1,1'-Biphenyl]-4-methanol,4'-methoxy- (CAS No. 20854-60-8) is a multifaceted compound with broad applications in science and technology. Its relevance in green chemistry, drug development, and advanced materials underscores its importance in contemporary research. As innovation continues, this compound is likely to play an even more prominent role in addressing challenges across these fields.

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