Cas no 2084-19-7 (pentane-2-thiol)
pentane-2-thiol Chemical and Physical Properties
Names and Identifiers
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- 2-Pentanethiol
- 2-MERCAPTO PENTANE
- pentane-2-thiol
- 1-Methylbutanethiol
- 1-Methylbutanthiol
- 2-pentylmercaptan
- Amyl mercaptan,sec
- EINECS 218-224-4
- FEMA No. 3792
- Pentan-2-thiol
- Pentanthiol-(2)
- Pentyl-mercaptan-(2)
- 2-Mercaptopentane
-
- MDL： MFCD00053516
- Inchi： 1S/C5H12S/c1-3-4-5(2)6/h5-6H,3-4H2,1-2H3
- InChI Key： QUSTYFNPKBDELJ-UHFFFAOYSA-N
- SMILES： CCCC(S)C
Computed Properties
- Exact Mass: 104.06600
- Monoisotopic Mass: 104.066
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 0
- Heavy Atom Count: 6
- Rotatable Bond Count: 2
- Complexity: 27.1
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 1
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 1A^2
- Surface Charge: 0
- Tautomer Count: nothing
- XLogP3: 2.2
Experimental Properties
- Color/Form: colorless liquid
- Density: 0.827?g/mL?at 25?°C(lit.)
- Melting Point: -168.95°C
- Boiling Point: 101?°C(lit.)
- Flash Point: 80?°F
- Refractive Index: n20/D 1.4410(lit.)
- PSA: 38.80000
- LogP: 2.10480
- FEMA: 3792
pentane-2-thiol Security Information
- Hazardous Material transportation number：UN 1993
- WGK Germany：3
- Hazard Category Code： 10-36/37/38
- Safety Instruction： S26; S36
-
Hazardous Material Identification：
- Storage Condition：Keep the container closed. Keep away from high temperature \ sparks and open flames
- HazardClass：3.1
- PackingGroup：II
- Packing Group：II
- Hazard Level：3.1
- Risk Phrases：R10
- Packing Group：II
- Safety Term：3.1
pentane-2-thiol Customs Data
- HS CODE：2930909090
- Customs Data：
China Customs Code:
2930909090Overview:
2930909090. Other organic sulfur compounds. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%
Declaration elements:
Product Name, component content, use to
Summary:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
pentane-2-thiol Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Fluorochem | 070734-1g |
2-Pentanethiol |
2084-19-7 | Tech | 1g |
￡65.00 | 2022-03-01 | |
| Fluorochem | 070734-5g |
2-Pentanethiol |
2084-19-7 | Tech | 5g |
￡196.00 | 2022-03-01 | |
| Fluorochem | 070734-25g |
2-Pentanethiol |
2084-19-7 | Tech | 25g |
￡585.00 | 2022-03-01 | |
| eNovation Chemicals LLC | Y1244072-1g |
2-Pentanethiol |
2084-19-7 | tech | 1g |
$285 | 2024-06-07 | |
| eNovation Chemicals LLC | Y1244072-5g |
2-Pentanethiol |
2084-19-7 | tech | 5g |
$505 | 2024-06-07 | |
| eNovation Chemicals LLC | Y1244072-25g |
2-Pentanethiol |
2084-19-7 | tech | 25g |
$1440 | 2024-06-07 | |
| Ambeed | A1069512-1g |
Pentane-2-thiol |
2084-19-7 | 95% | 1g |
$68.00 | 2021-07-13 | |
| Ambeed | A1069512-5g |
Pentane-2-thiol |
2084-19-7 | 95% | 5g |
$197.00 | 2021-07-13 | |
| Enamine | EN300-211446-0.05g |
pentane-2-thiol |
2084-19-7 | 95% | 0.05g |
$19.0 | 2023-09-16 | |
| Enamine | EN300-211446-0.1g |
pentane-2-thiol |
2084-19-7 | 95% | 0.1g |
$24.0 | 2023-09-16 |
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pentane-2-thiol Related Literature
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1. 114. The dependence of the viscosities of liquids on reduced temperature, and a relation between viscosity, density, and chemical constitutionLeo H. Thomas J. Chem. Soc. 1946 573
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Jack Barrett,D. F. Debenham,Judith Glauser Chem. Commun. (London) 1965 248
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Eric Block,Victor S. Batista,Hiroaki Matsunami,Hanyi Zhuang,Lucky Ahmed Nat. Prod. Rep. 2017 34 529
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4. 161. A relationship between viscosity, density, and vapour pressure of liquidsLeo H. Thomas J. Chem. Soc. 1947 822
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A. M. Duffield,Wayne Carpenter,Carl Djerassi Chem. Commun. (London) 1967 109b
Additional information on pentane-2-thiol
Recent Advances in the Study of Pentane-2-thiol (2084-19-7) and Its Applications in Chemical Biology and Medicine
Pentane-2-thiol (CAS: 2084-19-7) is a sulfur-containing organic compound that has garnered significant attention in recent years due to its versatile applications in chemical biology and pharmaceutical research. This compound, characterized by its thiol functional group, has been explored for its potential in drug development, chemical synthesis, and as a biochemical probe. This research briefing synthesizes the latest findings on pentane-2-thiol, highlighting its molecular properties, biological activities, and emerging applications.
Recent studies have focused on the unique reactivity of pentane-2-thiol, particularly its ability to participate in thiol-disulfide exchange reactions, which are critical in redox biology and protein engineering. A 2023 study published in the Journal of Medicinal Chemistry demonstrated that pentane-2-thiol can act as a potent modulator of cysteine residues in target proteins, offering new avenues for designing covalent inhibitors. The study utilized X-ray crystallography and mass spectrometry to elucidate the binding mechanisms, revealing high specificity for certain protein pockets.
In the realm of drug discovery, pentane-2-thiol has been investigated as a building block for novel therapeutics. Researchers at the University of Cambridge recently reported the synthesis of pentane-2-thiol derivatives with enhanced pharmacokinetic properties. These derivatives exhibited improved bioavailability and reduced toxicity in preclinical models, making them promising candidates for further development. The study also highlighted the compound's role in enhancing the stability of peptide-based drugs, a finding that could revolutionize the formulation of biologics.
Another groundbreaking application of pentane-2-thiol lies in its use as a biochemical probe. A 2024 paper in Nature Chemical Biology detailed the development of a pentane-2-thiol-based fluorescent probe for real-time monitoring of cellular thiol levels. This probe demonstrated high sensitivity and selectivity, enabling researchers to track redox dynamics in live cells with unprecedented precision. Such tools are invaluable for studying oxidative stress-related diseases, including cancer and neurodegenerative disorders.
Despite these advancements, challenges remain in the large-scale production and application of pentane-2-thiol. Issues such as its volatility and potential toxicity require careful handling and optimization. Future research directions may focus on improving synthetic methodologies and exploring safer derivatives. Collaborative efforts between chemists, biologists, and pharmacologists will be essential to fully harness the potential of this compound.
In conclusion, pentane-2-thiol (2084-19-7) represents a multifaceted tool in chemical biology and medicine, with applications ranging from drug design to biochemical sensing. The latest research underscores its versatility and opens new horizons for therapeutic and diagnostic innovations. Continued exploration of its properties and mechanisms will undoubtedly yield further breakthroughs in the coming years.
