Cas no 207346-42-7 (Methyl 2-amino-4,5-difluorobenzoate)

Methyl 2-amino-4,5-difluorobenzoate is a fluorinated aromatic ester with a reactive amino group, making it a versatile intermediate in organic synthesis. Its difluorinated benzene ring enhances electron-withdrawing properties, which can be advantageous in the development of pharmaceuticals, agrochemicals, and specialty materials. The presence of both amino and ester functional groups allows for further derivatization, enabling applications in cross-coupling reactions, amide formations, and heterocyclic syntheses. The compound's stability under standard conditions ensures ease of handling and storage. Its structural features make it particularly useful in designing bioactive molecules where fluorine substitution is critical for modulating metabolic stability and binding affinity.

Methyl 2-amino-4,5-difluorobenzoate structure

207346-42-7 structure

Product Name:Methyl 2-amino-4,5-difluorobenzoate

CAS No:207346-42-7

MF:C₈H₇F₂NO₂

MW:187.143489122391

MDL:MFCD09264511

CID:66757

PubChem ID:18472001

Update Time:2025-08-04

Methyl 2-amino-4,5-difluorobenzoate Chemical and Physical Properties

Names and Identifiers

- Methyl 2-amino-4,5-difluorobenzoate
- Benzoic acid, 2-amino-4,5-difluoro-, methyl ester (9CI)
- Methyl-2-amino-4,5-difluoro Benzoate
- 2-amino-4,5-difluoro-benzoic acid,methyl ester
- methyl 4,5-difluoroanthranilate,methyl ester
- 2-Amino-4,5-difluorobenzoicacid methyl ester
- 2-AMINO-4,5-DIFLUOROBENZOIC ACID METHYL ESTER
- Benzoic acid, 2-amino-4,5-difluoro-, methyl ester
- PubChem4676
- KSC496G7J
- Methyl 4,5-difluoroanthranilate
- VIAQNTRKUPBQKR-UHFFFAOYSA-N
- WT267
- BCP27364
- Methyl2-Amino-4,5-difluorobenzoate
- STL554923
- TD1173
- SBB053777
- BBL101127
- methyl 2-amino-4,5-difluoro-benzoate
- MFCD09264511
- FT-0602107
- MFCD092664511
- DTXSID10594187
- EN300-85662
- J-521919
- CS-W003614
- SCHEMBL195591
- AM20060202
- 207346-42-7
- AKOS005063666
- TS-02625
- AC-3876
- Z594218556
- Methyl 2-amino-4,5-difluorobenzoate, AldrichCPR
- SY014552
- DB-007645
- MDL： MFCD09264511
- Inchi： 1S/C8H7F2NO2/c1-13-8(12)4-2-5(9)6(10)3-7(4)11/h2-3H,11H2,1H3
- InChI Key： VIAQNTRKUPBQKR-UHFFFAOYSA-N
- SMILES： FC1C(=CC(=C(C(=O)OC)C=1)N)F

Computed Properties

Exact Mass: 187.04400
Monoisotopic Mass: 187.044
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 5
Heavy Atom Count: 13
Rotatable Bond Count: 2
Complexity: 201
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Topological Polar Surface Area: 52.3
XLogP3: 1.8

Experimental Properties

Color/Form: Pale yellow crystal
Density: 1.355
Melting Point: No data available
Boiling Point: 274.1 °C at 760 mmHg
Flash Point: 274.1 °C at 760 mmHg
Refractive Index: 1.524
PSA: 52.32000
LogP: 1.91480

Methyl 2-amino-4,5-difluorobenzoate Security Information

Signal Word：warning
Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
Warning Statement： P264Thoroughly clean after treatment
P280Wear protective gloves/Wear protective clothing/Wear protective goggles/Wear a protective mask
P305If it enters the eyes
P351Rinse carefully with water for a few minutes
P338Remove the contact lens(If any)And easy to operate,Continue flushing
P337If eye irritation persists
P313Obtain medical advice/care
Safety Instruction： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
Storage Condition：Store at 4°C,-4At ℃Store…Better

Methyl 2-amino-4,5-difluorobenzoate Customs Data

HS CODE：2922499990
Customs Data：

China Customs Code:
2922499990

Overview:

2922499990 Other amino acids and their esters and their salts(Except those containing more than one oxygen-containing group). VAT:17.0% Tax refund rate:9.0% Regulatory conditions:AB(Customs clearance form for Inbound Goods,Customs clearance form for outbound goods) MFN tariff:6.5% general tariff:30.0%

Declaration elements:

Product Name, component content, use to, The color of ethanolamine and its salt should be reported, The package of ethanolamine and its salt shall be declared

Regulatory conditions:

A.Customs clearance form for Inbound Goods
B.Customs clearance form for outbound goods

Inspection and quarantine category:

P.Imported animals and plants\Quarantine of animal and plant products
Q.Outbound animals and plants\Quarantine of animal and plant products
R.Sanitary supervision and inspection of imported food
S.Sanitary supervision and inspection of exported food
M.Import commodity inspection
N.Export commodity inspection

Summary:

HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Methyl 2-amino-4,5-difluorobenzoate Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
SHANG HAI XIAN DING Biotechnology Co., Ltd.	M230A-100g	Methyl 2-amino-4,5-difluorobenzoate	207346-42-7	98%	100g	￥936.0	2022-06-10
SHANG HAI XIAN DING Biotechnology Co., Ltd.	M230A-5g	Methyl 2-amino-4,5-difluorobenzoate	207346-42-7	98%	5g	￥72.0	2022-06-10
SHANG HAI XIAN DING Biotechnology Co., Ltd.	M230A-25g	Methyl 2-amino-4,5-difluorobenzoate	207346-42-7	98%	25g	￥259.0	2022-06-10
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.	M132553-5g	Methyl 2-amino-4,5-difluorobenzoate	207346-42-7	98%	5g	￥60.90	2023-09-02
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.	M132553-100g	Methyl 2-amino-4,5-difluorobenzoate	207346-42-7	98%	100g	￥825.90	2023-09-02
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.	M132553-25g	Methyl 2-amino-4,5-difluorobenzoate	207346-42-7	98%	25g	￥220.90	2023-09-02
Fluorochem	066846-5g	Methyl 2-Amino-4,5-difluorobenzoate	207346-42-7	97%	5g	￡12.00	2022-03-01
Fluorochem	066846-10g	Methyl 2-Amino-4,5-difluorobenzoate	207346-42-7	97%	10g	￡17.00	2022-03-01
Fluorochem	066846-25g	Methyl 2-Amino-4,5-difluorobenzoate	207346-42-7	97%	25g	￡34.00	2022-03-01
Fluorochem	066846-100g	Methyl 2-Amino-4,5-difluorobenzoate	207346-42-7	97%	100g	￡126.00	2022-03-01

Methyl 2-amino-4,5-difluorobenzoate Suppliers

Amadis Chemical Company Limited

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Audited Supplier

(CAS:207346-42-7)Methyl 2-amino-4,5-difluorobenzoate

Order Number:A15363

Stock Status:in Stock

Quantity:500g

Purity:99%

Pricing Information Last Updated:Friday, 30 August 2024 04:02

Price ($):400.0

Email:[email protected]

Product Official Link

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Additional information on Methyl 2-amino-4,5-difluorobenzoate

Methyl 2-Amino-4,5-Difluorobenzoate (CAS No. 207346-42-7): A Comprehensive Overview

Methyl 2-amino-4,5-difluorobenzoate, also known by its CAS number 207346-42-7, is a compound of significant interest in the fields of organic chemistry and materials science. This compound is a derivative of benzoic acid, with a methyl group attached to the carboxylate and fluorine atoms at the 4 and 5 positions of the benzene ring. The presence of amino and fluoro substituents makes it a versatile molecule with potential applications in drug design, agrochemicals, and advanced materials.

The synthesis of methyl 2-amino-4,5-difluorobenzoate typically involves multi-step processes that include fluorination, amination, and esterification reactions. Recent advancements in catalytic methods have enabled more efficient syntheses, reducing production costs and environmental impact. For instance, researchers have explored the use of transition metal catalysts to facilitate the fluorination step, achieving higher yields and better purity levels.

One of the most promising applications of this compound lies in its potential as a building block for pharmaceuticals. The amino group can act as a nucleophilic site for further functionalization, while the fluoro groups provide electronic tuning to modulate biological activity. Recent studies have shown that derivatives of methyl 2-amino-4,5-difluorobenzoate exhibit potent inhibitory effects on certain enzymes associated with neurodegenerative diseases. These findings highlight its role in drug discovery pipelines targeting conditions such as Alzheimer's disease.

In addition to its pharmaceutical applications, methyl 2-amino-4,5-difluorobenzoate has shown promise in agrochemical research. Its ability to interact with specific receptors in plant systems makes it a candidate for developing new pesticides or growth regulators. Field trials conducted in controlled environments have demonstrated its efficacy in enhancing crop resilience against fungal infections without adverse environmental effects.

The electronic properties of this compound also make it an attractive candidate for use in organic electronics. The fluorine atoms contribute to the molecule's stability and ability to conduct electricity under certain conditions. Researchers are exploring its potential as a component in organic light-emitting diodes (OLEDs) and flexible electronics. Initial results suggest that incorporating methyl 2-amino-4,5-difluorobenzoate into polymer blends can improve device performance metrics such as luminous efficiency and operational lifetime.

From an environmental standpoint, understanding the fate and transport of methyl 2-amino-4,5-difluorobenzoate in natural systems is crucial for risk assessment. Studies using advanced analytical techniques have revealed that this compound undergoes rapid degradation under UV light exposure but persists longer in anaerobic conditions. These insights are vital for developing guidelines on its safe handling and disposal.

In conclusion, methyl 2-amino-4,5-difluorobenzoate (CAS No. 207346-42-7) stands out as a multifaceted compound with diverse applications across various scientific domains. Its unique chemical structure offers opportunities for innovation in drug development, agriculture, and electronics while posing challenges related to environmental safety. As research continues to uncover new properties and uses for this compound, its significance in modern chemistry is likely to grow further.

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