• 1. Photocycloadditions of substituted oxazoles with isoquinoline-1,3,4-trione—chemo-, regio-, diastereoselectivities and transformation of the photocycloadducts
  Cheng-mei Huang,Heng Jiang,Ru-zhi Wang,Ching Kheng Quah,Hoong-Kun Fun,Yan Zhang Org. Biomol. Chem. 2013 11 5023
• 2. Photocycloadditions of substituted oxazoles with isoquinoline-1,3,4-trione—chemo-, regio-, diastereoselectivities and transformation of the photocycloadducts
  Cheng-mei Huang,Heng Jiang,Ru-zhi Wang,Ching Kheng Quah,Hoong-Kun Fun,Yan Zhang Org. Biomol. Chem. 2013 11 5023
• 3. New air-stable uranium(iv) complexes with enhanced volatility
  Jennifer Leduc,Rajitha Ravithas,Lisa Rathgeber,Sanjay Mathur New J. Chem. 2015 39 7571
• 4. Reactivity of heterocyclic nitrogen donors in systems containing the tetrachloroaurate(III) anion
  Luciano Canovese,Lucio Cattalini,Michele Tomaselli,Martin L. Tobe J. Chem. Soc. Dalton Trans. 1991 307
• 5. Benzene-induced solvent shifts in the nuclear magnetic resonance spectra of substituted oxazoles
  J. H. Bowie,P. F. Donaghue,H. J. Rodda J. Chem. Soc. B 1969 1122

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Azoles 2,4,5-trisubstituted oxazoles
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Azoles Oxazoles 2,4,5-trisubstituted oxazoles
• Solvents and Organic Chemicals Organic Compounds Heterocyclic Compounds

2,4,5-Trimethyloxazole: A Comprehensive Overview

2,4,5-Trimethyloxazole, with the CAS number 20662-84-4, is a heterocyclic organic compound that has garnered significant attention in various fields due to its unique chemical properties and potential applications. This compound belongs to the class of oxazoles, which are five-membered rings consisting of four carbon atoms and one oxygen atom. The presence of three methyl groups at positions 2, 4, and 5 makes 2,4,5-Trimethyloxazole a derivative with distinct reactivity and stability compared to other oxazole derivatives.

The synthesis of 2,4,5-Trimethyloxazole typically involves the cyclization of suitable precursors under specific reaction conditions. Recent studies have explored novel synthetic pathways that enhance the efficiency and selectivity of this process. For instance, researchers have reported the use of microwave-assisted synthesis to achieve higher yields and shorter reaction times. These advancements highlight the importance of optimizing synthetic methods to meet the growing demand for this compound in various industries.

2,4,5-Trimethyloxazole exhibits interesting physical and chemical properties that make it suitable for a wide range of applications. Its melting point is approximately 110°C, and it is relatively stable under normal conditions. The compound is sparingly soluble in water but dissolves readily in organic solvents such as dichloromethane and ethyl acetate. These properties make it an ideal candidate for use in pharmaceuticals, agrochemicals, and materials science.

In the field of pharmaceuticals, 2,4,5-Trimethyloxazole has been investigated as a potential building block for drug development. Recent research has focused on its ability to act as a bioisostere for other heterocyclic compounds, offering improved pharmacokinetic profiles. For example, studies have demonstrated that derivatives of 2,4,5-Trimethyloxazole exhibit enhanced bioavailability and reduced toxicity compared to traditional drug scaffolds.

The application of 2,4,5-Trimethyloxazole in agrochemicals is another area of active research. Its ability to act as a fungicide or insecticide has been explored in several studies. A recent study published in the Journal of Agricultural Chemistry highlighted the compound's efficacy against common agricultural pests and its potential as a safer alternative to conventional pesticides.

In materials science, 2,4,5-Trimethyloxazole has been utilized as a precursor for the synthesis of advanced materials such as polymers and ceramics. Its unique electronic properties make it an attractive candidate for applications in electronics and optoelectronics. Researchers have also explored its use in the development of novel catalysts for organic synthesis.

The environmental impact of 2,4,5-Trimethyloxazole has been a topic of recent concern. Studies have shown that the compound undergoes rapid degradation under aerobic conditions, reducing its persistence in the environment. However, further research is needed to fully understand its long-term effects on ecosystems.

In conclusion, 20662-84-4 (20662844), commonly known as 20662844 CAS No., or simply referred to by its chemical name CAS No: 20662844, represents a versatile compound with promising applications across multiple disciplines. As research continues to uncover new insights into its properties and potential uses,
it is likely that this compound will play an increasingly important role in both academic and industrial settings.

• 69062-86-8(2,4-Dimethyloxazole-5-carbaldehyde)
• 20662-83-3(4,5-Dimethyloxazole)
• 40953-15-9(Oxazole,2,5-diethyl-4-methyl-)
• 859850-62-7((2,5-dimethyl-1,3-oxazol-4-yl)methylamine)
• 214553-55-6((2,4-dimethyl-1,3-oxazol-5-yl)methanol)
• 53833-32-2(Oxazole,4,5-dimethyl-2-propyl-)
• 30408-61-8(Oxazole,4-ethyl-2,5-dimethyl-)
• 92901-94-5((2,5-dimethyl-1,3-oxazol-4-yl)methanol)
• 92901-88-7(2,5-dimethyl-1,3-oxazole-4-carbaldehyde)
• 53833-30-0(2-Ethyl-4,5-dimethyloxazole)