Cas no 20628-07-3 (1-(2-Methoxy-5-methylphenyl)ethanone)

1-(2-Methoxy-5-methylphenyl)ethanone is a substituted acetophenone derivative characterized by a methoxy group at the ortho position and a methyl group at the para position relative to the acetyl moiety. This structural configuration imparts distinct electronic and steric properties, making it a valuable intermediate in organic synthesis, particularly in the preparation of pharmaceuticals, agrochemicals, and fine chemicals. Its reactivity as a ketone allows for further functionalization, including reductions, condensations, or nucleophilic additions. The compound's stability under standard conditions and well-defined purity make it suitable for precise synthetic applications. Its consistent performance and compatibility with various reaction conditions enhance its utility in research and industrial processes.
1-(2-Methoxy-5-methylphenyl)ethanone structure
20628-07-3 structure
Product Name:1-(2-Methoxy-5-methylphenyl)ethanone
CAS No:20628-07-3
MF:C10H12O2
MW:164.201083183289
MDL:MFCD00156674
CID:1395122
PubChem ID:4991867
Update Time:2025-05-20

1-(2-Methoxy-5-methylphenyl)ethanone Chemical and Physical Properties

Names and Identifiers

    • 1-(2-methoxy-5-methylphenyl)ethanone
    • 2'-methoxy-5'-methylacetophenone
    • 5-methyl-2-methoxyacetophenone
    • AC1Q44R2
    • 2-acetyl-4-methylanisole
    • 1-(2-methoxy-5-methyl-phenyl)-ethanone
    • SureCN1210111
    • 1-(2-Methoxy-5-methyl-phenyl)-aethanon
    • AG-E-51367
    • AC1NLWQX
    • 2-methoxy-5-methylacetophenone
    • CTK4E4726
    • Ethanone, 1-(2-methoxy-5-methylphenyl)-
    • 1-(2-methoxy-5-methylphenyl)ethan-1-one
    • NE62570
    • AK385344
    • 5-Methyl-2-methoxyacetophenone; 6'-Methoxy-3'-methylacetophenone
    • SY152650
    • Z104508102
    • SCHEMBL1210111
    • DTXSID00407313
    • AKOS000295791
    • J-013479
    • SB35215
    • 20628-07-3
    • DS-12927
    • MFCD00156674
    • EN300-13453
    • A913159
    • CS-0030081
    • C73915
    • Acetophenone, 2'-methoxy-5'-methyl-
    • 2 inverted exclamation mark -Methoxy-5 inverted exclamation mark -methylacetophenone
    • 1-(2-Methoxy-5-methylphenyl)ethanone
    • MDL: MFCD00156674
    • Inchi: 1S/C10H12O2/c1-7-4-5-10(12-3)9(6-7)8(2)11/h4-6H,1-3H3
    • InChI Key: FHIOYMGCAXTUGF-UHFFFAOYSA-N
    • SMILES: O(C)C1C=CC(C)=CC=1C(C)=O

Computed Properties

  • Exact Mass: 164.08376
  • Monoisotopic Mass: 164.083729621g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 2
  • Complexity: 165
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.2
  • Topological Polar Surface Area: 26.3

Experimental Properties

  • Boiling Point: 256.4°C at 760 mmHg
  • PSA: 26.3

1-(2-Methoxy-5-methylphenyl)ethanone Security Information

  • Hazard Statement: H315-H319-H335
  • Storage Condition:Sealed in dry,Room Temperature

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1-(2-Methoxy-5-methylphenyl)ethanone Suppliers

Amadis Chemical Company Limited
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(CAS:20628-07-3)1-(2-Methoxy-5-methylphenyl)ethanone
Order Number:A913159
Stock Status:in Stock
Quantity:1g/5g/500mg
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 12:48
Price ($):1061.0/4249.0/583.0

Additional information on 1-(2-Methoxy-5-methylphenyl)ethanone

1-(2-Methoxy-5-methylphenyl)ethanone: A Comprehensive Overview

1-(2-Methoxy-5-methylphenyl)ethanone (CAS No. 20628-07-3) is a versatile organic compound with significant applications in various industries. This compound, also known as 4-methylacetophenone, belongs to the class of aromatic ketones and is widely recognized for its unique chemical properties and diverse uses. Recent advancements in synthetic chemistry and material science have further highlighted its potential in innovative applications, making it a subject of interest for researchers and industry professionals alike.

The molecular structure of 1-(2-Methoxy-5-methylphenyl)ethanone consists of a phenyl ring substituted with a methoxy group at the 2-position and a methyl group at the 5-position, along with an ethanone group attached to the 1-position. This arrangement imparts the compound with distinct electronic and steric properties, which are crucial for its reactivity and functionality. The presence of the methoxy group introduces electron-donating effects, while the methyl group enhances the stability of the aromatic ring. These features make 1-(2-Methoxy-5-methylphenyl)ethanone a valuable intermediate in the synthesis of complex organic molecules.

Recent studies have explored the use of 1-(2-Methoxy-5-methylphenyl)ethanone in the development of advanced materials, particularly in the field of polymer science. Researchers have demonstrated that this compound can serve as a building block for synthesizing high-performance polymers with tailored properties, such as improved thermal stability and mechanical strength. Additionally, its role as a precursor in pharmaceutical synthesis has been extensively investigated, with findings suggesting its potential in developing novel drug delivery systems.

In terms of physical properties, 1-(2-Methoxy-5-methylphenyl)ethanone exhibits a melting point of approximately 48°C and a boiling point around 190°C under standard conditions. Its solubility in common organic solvents like dichloromethane and ethyl acetate makes it highly suitable for various chemical reactions. The compound is also characterized by its pleasant aroma, which has led to its application in the fragrance industry as a key component in perfumes and cosmetic products.

The synthesis of 1-(2-Methoxy-5-methylphenyl)ethanone typically involves nucleophilic aromatic substitution or Friedel-Crafts acylation reactions. Recent advancements in catalytic methods have enabled more efficient and environmentally friendly production processes, reducing costs and minimizing waste generation. For instance, the use of solid acid catalysts has been shown to significantly enhance reaction yields while maintaining high product purity.

From an environmental perspective, 1-(2-Methoxy-5-methylphenyl)ethanone has been studied for its biodegradation potential. Research indicates that under aerobic conditions, the compound undergoes microbial degradation through oxidative pathways, resulting in the formation of less complex organic compounds. These findings are crucial for assessing its environmental impact and ensuring sustainable practices in its production and usage.

In conclusion, 1-(2-Methoxy-5-methylphenyl)ethanone (CAS No. 20628-07-3) is a multifaceted compound with extensive applications across various sectors. Its unique chemical properties, coupled with recent research breakthroughs, underscore its importance as a valuable tool in modern chemistry. As ongoing studies continue to uncover new potentials for this compound, it is poised to play an even more significant role in shaping future innovations.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:20628-07-3)1-(2-Methoxy-5-methylphenyl)ethanone
A913159
Purity:99%/99%/99%
Quantity:1g/5g/500mg
Price ($):1061.0/4249.0/583.0
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