Cas no 2044712-87-8 (Ethyl 2-amino-4-(difluoromethyl)-1,3-oxazole-5-carboxylate)

Ethyl 2-amino-4-(difluoromethyl)-1,3-oxazole-5-carboxylate is a fluorinated oxazole derivative with notable applications in medicinal and agrochemical research. Its key structural features include a difluoromethyl group at the 4-position and an ester functionality at the 5-position, enhancing its reactivity and potential as a versatile intermediate. The presence of the 2-amino group further increases its utility in heterocyclic synthesis, particularly in the development of bioactive compounds. This compound exhibits favorable stability and solubility properties, making it suitable for diverse synthetic transformations. Its unique fluorinated oxazole core is of interest in the design of pharmaceuticals and crop protection agents, where fluorine incorporation often improves metabolic stability and bioavailability.
Ethyl 2-amino-4-(difluoromethyl)-1,3-oxazole-5-carboxylate structure
2044712-87-8 structure
Product Name:Ethyl 2-amino-4-(difluoromethyl)-1,3-oxazole-5-carboxylate
CAS No:2044712-87-8
MF:C7H8F2N2O3
MW:206.146828651428
MDL:MFCD30486613
CID:4634405
PubChem ID:125449043
Update Time:2025-06-07

Ethyl 2-amino-4-(difluoromethyl)-1,3-oxazole-5-carboxylate Chemical and Physical Properties

Names and Identifiers

    • ethyl 2-amino-4-(difluoromethyl)-1,3-oxazole-5-carboxylate
    • E74118
    • Ethyl 2-amino-4-(difluoromethyl)-1,3-oxazole-5-carboxylate
    • MDL: MFCD30486613
    • Inchi: 1S/C7H8F2N2O3/c1-2-13-6(12)4-3(5(8)9)11-7(10)14-4/h5H,2H2,1H3,(H2,10,11)
    • InChI Key: KTDPYJBYVHHHRI-UHFFFAOYSA-N
    • SMILES: FC(C1=C(C(=O)OCC)OC(N)=N1)F

Computed Properties

  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 7
  • Heavy Atom Count: 14
  • Rotatable Bond Count: 4
  • Complexity: 215
  • XLogP3: 1.2
  • Topological Polar Surface Area: 78.4

Ethyl 2-amino-4-(difluoromethyl)-1,3-oxazole-5-carboxylate Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Chemenu
CM443206-100mg
ethyl 2-amino-4-(difluoromethyl)-1,3-oxazole-5-carboxylate
2044712-87-8 95%+
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Chemenu
CM443206-250mg
ethyl 2-amino-4-(difluoromethyl)-1,3-oxazole-5-carboxylate
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ethyl 2-amino-4-(difluoromethyl)-1,3-oxazole-5-carboxylate
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Enamine
EN300-318278-0.05g
ethyl 2-amino-4-(difluoromethyl)-1,3-oxazole-5-carboxylate
2044712-87-8 95.0%
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$174.0 2025-03-19
Enamine
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ethyl 2-amino-4-(difluoromethyl)-1,3-oxazole-5-carboxylate
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Enamine
EN300-318278-0.25g
ethyl 2-amino-4-(difluoromethyl)-1,3-oxazole-5-carboxylate
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Enamine
EN300-318278-0.5g
ethyl 2-amino-4-(difluoromethyl)-1,3-oxazole-5-carboxylate
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Enamine
EN300-318278-1.0g
ethyl 2-amino-4-(difluoromethyl)-1,3-oxazole-5-carboxylate
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Enamine
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