Cas no 204319-69-7 (4-(trifluoromethyl)-1,3-thiazol-2-ylmethanol)
4-(Trifluoromethyl)-1,3-thiazol-2-ylmethanol is a fluorinated thiazole derivative characterized by the presence of a trifluoromethyl group and a hydroxymethyl substituent on the thiazole ring. This structural motif imparts unique physicochemical properties, including enhanced lipophilicity and metabolic stability, making it a valuable intermediate in pharmaceutical and agrochemical synthesis. The trifluoromethyl group contributes to electron-withdrawing effects, influencing reactivity and binding interactions, while the hydroxymethyl functionality allows for further derivatization. Its applications include use in the development of bioactive molecules, particularly in medicinal chemistry for drug discovery. The compound’s stability and versatility underscore its utility in synthetic organic chemistry.
204319-69-7 structure
Product Name:4-(trifluoromethyl)-1,3-thiazol-2-ylmethanol
CAS No:204319-69-7
MF:C5H4F3NOS
MW:183.151570320129
MDL:MFCD09909578
CID:1023805
PubChem ID:23560688
Update Time:2025-10-14
4-(trifluoromethyl)-1,3-thiazol-2-ylmethanol Chemical and Physical Properties
Names and Identifiers
-
- (4-(Trifluoromethyl)thiazol-2-yl)methanol
- [4-(trifluoromethyl)-1,3-thiazol-2-yl]methanol
- 2-Thiazolemethanol, 4-(trifluoromethyl)-
- (4-(trifluoromethyl)-1,3-thiazol-2-yl)methanol
- VIGAFTQUOHZWIC-UHFFFAOYSA-N
- 0482AB
- NE25113
- 4-Trifluoromethyl-thiazol-2-yl-methanol
- AK102461
- [4-Trifluoromethyl-1,3-thiazol-2-yl]methanol
- (4-Trifluoromethyl-thiazol-2-yl)-methanol
- F13125
- DS-3849
- SCHEMBL485332
- DB-327790
- A849472
- 204319-69-7
- Z1037609670
- AKOS012221041
- DTXSID00634965
- SB35194
- EN300-157634
- MFCD09909578
- 4-(trifluoromethyl)-1,3-thiazol-2-ylmethanol
-
- MDL： MFCD09909578
- Inchi： 1S/C5H4F3NOS/c6-5(7,8)3-2-11-4(1-10)9-3/h2,10H,1H2
- InChI Key： VIGAFTQUOHZWIC-UHFFFAOYSA-N
- SMILES： S1C=C(C(F)(F)F)N=C1CO
Computed Properties
- Exact Mass: 182.99656941g/mol
- Monoisotopic Mass: 182.99656941g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 6
- Heavy Atom Count: 11
- Rotatable Bond Count: 1
- Complexity: 140
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 61.4
- XLogP3: 1
Experimental Properties
- Boiling Point: 205.1±40.0°C at 760 mmHg
4-(trifluoromethyl)-1,3-thiazol-2-ylmethanol Security Information
- Signal Word：Warning
- Hazard Statement： H302-H319
- Warning Statement： P305+P351+P338
- Storage Condition：Sealed in dry,2-8°C
4-(trifluoromethyl)-1,3-thiazol-2-ylmethanol Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A059006074-5g |
(4-(Trifluoromethyl)thiazol-2-yl)methanol |
204319-69-7 | 97% | 5g |
$950.00 | 2023-09-02 | |
| Alichem | A059006074-10g |
(4-(Trifluoromethyl)thiazol-2-yl)methanol |
204319-69-7 | 97% | 10g |
$1546.60 | 2023-09-02 | |
| Alichem | A059006074-25g |
(4-(Trifluoromethyl)thiazol-2-yl)methanol |
204319-69-7 | 97% | 25g |
$2270.12 | 2023-09-02 | |
| Fluorochem | 227496-250mg |
4-(Trifluoromethyl)thiazol-2-yl)methanol |
204319-69-7 | 95% | 250mg |
￡65.00 | 2022-02-28 | |
| Fluorochem | 227496-1g |
4-(Trifluoromethyl)thiazol-2-yl)methanol |
204319-69-7 | 95% | 1g |
￡195.00 | 2022-02-28 | |
| Fluorochem | 227496-5g |
4-(Trifluoromethyl)thiazol-2-yl)methanol |
204319-69-7 | 95% | 5g |
￡774.00 | 2022-02-28 | |
| Chemenu | CM189927-1g |
(4-(trifluoromethyl)thiazol-2-yl)methanol |
204319-69-7 | 97% | 1g |
$407 | 2021-08-05 | |
| Chemenu | CM189927-5g |
(4-(trifluoromethyl)thiazol-2-yl)methanol |
204319-69-7 | 97% | 5g |
$1105 | 2021-08-05 | |
| Chemenu | CM189927-10g |
(4-(trifluoromethyl)thiazol-2-yl)methanol |
204319-69-7 | 97% | 10g |
$1638 | 2021-08-05 | |
| Chemenu | CM189927-25g |
(4-(trifluoromethyl)thiazol-2-yl)methanol |
204319-69-7 | 97% | 25g |
$2571 | 2021-08-05 |
4-(trifluoromethyl)-1,3-thiazol-2-ylmethanol Related Literature
-
Haitao Li,Yu Pan,Zhizhi Wang,Shan Chen,Ruixin Guo,Jianqiu Chen RSC Adv., 2015,5, 100775-100782
-
Huabin Zhang,Shaowu Du CrystEngComm, 2014,16, 4059-4068
-
Bo Cao,Yin Wei Chem. Commun., 2018,54, 2870-2873
-
Zhonghua Xiang,Chuanqi Fang,Sanhua Leng,Dapeng Cao J. Mater. Chem. A, 2014,2, 7662-7665
204319-69-7 (4-(trifluoromethyl)-1,3-thiazol-2-ylmethanol) Related Products
- 944900-55-4(4-(trifluoromethyl)-1,3-thiazole-2-carboxylic acid)
- 13750-63-5((4-methyl-1,3-thiazol-2-yl)methanol HydrochlorideDiscontinued; See B486220)
- 643725-70-6(4-(trifluoromethyl)-1,3-thiazol-2-ylmethanamine)
- 1849218-92-3(4-(Difluoromethyl)-2-methyl-thiazole)
- 133046-47-6((2-(Trifluoromethyl)thiazol-4-yl)methanol)
- 137929-13-6(2-methyl-4-(trifluoromethyl)-1,3-thiazole)
- 1864985-41-0(4-(Difluoromethyl)-2-(trifluoromethyl)thiazole)
- 1784465-64-0(4-(Difluoromethyl)-1,3-thiazole-2-carboxylic acid)
- 1781528-33-3(5-methyl-4-(trifluoromethyl)-1,3-thiazol-2-ylmethanol)
- 354587-75-0(4-(Trifluoromethyl)thiazole-2-carbaldehyde)
Recommended suppliers
Jiangsu Xinsu New Materials Co., Ltd
Gold Member
Audited Supplier
CN Supplier
Bulk
Hangzhou TSurgeX Pharmaceutical Technology Co., Ltd.
Gold Member
Audited Supplier
CN Supplier
Reagent
Zouping Mingyuan Import and Export Trading Co., Ltd
Gold Member
Audited Supplier
CN Supplier
Reagent
NewCan Biotech Limited
Gold Member
Audited Supplier
CN Supplier
Reagent
PRIBOLAB PTE.LTD
Gold Member
Audited Supplier
CN Supplier
Reagent
