• 1. Fe(ii)-Assisted one-pot synthesis of ultra-small core–shell Au–Pt nanoparticles as superior catalysts towards the HER and ORR?
  Yi Cao,Yujiao Xiahou,Lixiang Xing,Xiang Zhang,Hong Li,ChenShou Wu,Haibing Xia Nanoscale, 2020,12, 20456-20466
• 2. Establishing plasmon contribution to chemical reactions: alkoxyamines as a thermal probe?
  Olga Guselnikova,Gérard Audran,Jean-Patrick Joly,Andrii Trelin,Evgeny V. Tretyakov,Vaclav Svorcik,Oleksiy Lyutakov,Sylvain R. A. Marque Chem. Sci., 2021,12, 4154-4161
• 3. Emerging enantiomeric resolution materials with homochiral nano-fabrications
  Ji-Ping Wei Nanoscale, 2015,7, 11815-11832
• 4. Emulsion technologies for multicellular tumour spheroid radiation assays?
  Kay S. McMillan,Anthony G. McCluskey,Annette Sorensen,Marie Boyd,Michele Zagnoni Analyst, 2016,141, 100-110
• 5. EWOD-driven droplet microfluidic device integrated with optoelectronic tweezers as an automated platform for cellular isolation and analysis?
  Gaurav J. Shah,Eric P.-Y. Chiou,Ming C. Wu,Chang-Jin “CJ” Kim Lab Chip, 2009,9, 1732-1739

• Solvents and Organic Chemicals Organic Compounds Organic nitrogen compounds Organonitrogen compounds Sulfonylureas

Comprehensive Guide to N-[2-(azetidin-1-yl)-2-(thiophen-3-yl)ethyl]-3-methanesulfonyl-2-oxoimidazolidine-1-carboxamide (CAS No. 2034567-95-6)

N-[2-(azetidin-1-yl)-2-(thiophen-3-yl)ethyl]-3-methanesulfonyl-2-oxoimidazolidine-1-carboxamide (CAS No. 2034567-95-6) is a specialized organic compound with significant potential in pharmaceutical research and development. This compound features a unique molecular structure combining an azetidine ring, a thiophene moiety, and a methanesulfonyl-2-oxoimidazolidine group, making it an intriguing subject for medicinal chemistry studies. Researchers are particularly interested in its potential as a bioactive scaffold for drug discovery.

The compound's molecular formula and weight, along with its precise structural characteristics, contribute to its growing importance in drug design and chemical biology. Recent trends in pharmaceutical research have shown increased interest in such heterocyclic compounds, especially those containing azetidine and thiophene components, due to their demonstrated biological activities and drug-like properties.

One of the most searched questions regarding this compound relates to its synthetic route and purification methods. The synthesis typically involves multi-step organic reactions, with careful attention to protecting group strategies for the sensitive carboxamide functionality. Analytical techniques such as HPLC, NMR, and mass spectrometry are crucial for characterizing this compound and ensuring its purity for research applications.

In terms of pharmacological potential, preliminary studies suggest that compounds with similar structures have shown activity against various biological targets. The presence of both azetidine and thiophene rings in the same molecule makes this compound particularly interesting for exploring structure-activity relationships. Researchers are investigating its potential as a lead compound in several therapeutic areas, though specific applications remain under investigation.

The solubility profile and stability characteristics of this compound are frequent topics of inquiry among researchers. Like many heterocyclic carboxamides, it demonstrates specific solubility patterns in organic solvents and aqueous solutions, which are important considerations for formulation studies. Stability testing under various conditions (pH, temperature, light exposure) is essential for determining appropriate storage conditions.

From a market perspective, the demand for specialized pharmaceutical intermediates like this compound has been steadily increasing. The global focus on targeted drug discovery and personalized medicine has created new opportunities for such structurally complex molecules. Suppliers and manufacturers are responding to this demand by developing more efficient production methods and improved quality control protocols.

Recent advances in computational chemistry and molecular modeling have enabled researchers to better understand the three-dimensional structure and potential binding modes of this compound. These in silico approaches are valuable for predicting ADME properties (absorption, distribution, metabolism, and excretion) and guiding further synthetic modifications to optimize pharmacological profiles.

Quality control remains a critical aspect when working with this compound. Analytical methods development for impurity profiling and stability indicating assays are active areas of research. The pharmaceutical industry's increasing emphasis on quality by design principles has led to more rigorous characterization requirements for such specialized compounds.

For researchers considering working with this compound, it's important to note that proper handling procedures and safety precautions should always be followed, even though it's not classified as hazardous. Standard laboratory practices for handling organic compounds should be maintained, including the use of appropriate personal protective equipment and proper ventilation.

The future research directions for this compound may include exploring its potential in combination therapies, investigating its metabolic pathways, and developing more efficient synthetic methodologies. As the pharmaceutical industry continues to seek novel chemical entities with improved therapeutic profiles, compounds with this unique structural combination will likely remain important subjects of investigation.

In conclusion, N-[2-(azetidin-1-yl)-2-(thiophen-3-yl)ethyl]-3-methanesulfonyl-2-oxoimidazolidine-1-carboxamide represents an interesting case study in modern medicinal chemistry. Its complex structure and potential biological activities make it a valuable compound for pharmaceutical research, particularly in the context of current trends toward structure-based drug design and fragment-based discovery approaches.

• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)