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  Raheleh Torabi,Hedayatollah Ghourchian,Massoud Amanlou Org. Biomol. Chem., 2016,14, 8141-8153
• 2. An investigation of the electrochemical delithiation process of carbon coated α-Fe2O3nanoparticles
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• 3. An algal process treatment combined with the Fenton reaction for high concentrations of amoxicillin and cefradine
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• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Primary alcohols
• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Alcohols and polyols Primary alcohols

2-Penten-1-ol (CAS No. 20273-24-9): An Overview of Its Properties, Applications, and Recent Research

2-Penten-1-ol, also known as pent-2-en-1-ol or 2-pentenyl alcohol, is a versatile organic compound with the chemical formula C₅H₁₀O. It is a colorless liquid with a characteristic odor and is widely used in various industries, including pharmaceuticals, cosmetics, and chemical synthesis. This compound is identified by its CAS Number 20273-24-9, which is a unique identifier assigned by the Chemical Abstracts Service to ensure precise identification and tracking in scientific literature and databases.

The molecular structure of 2-penten-1-ol consists of a five-carbon chain with a double bond between the second and third carbon atoms and a hydroxyl group (-OH) attached to the first carbon atom. This configuration imparts unique chemical properties that make it valuable in various applications. The compound is soluble in water and many organic solvents, which enhances its utility in different formulations.

In the pharmaceutical industry, 2-penten-1-ol has been explored for its potential therapeutic applications. Recent studies have investigated its antimicrobial properties, which could be beneficial in developing new drugs or formulations to combat bacterial infections. For instance, a study published in the Journal of Medicinal Chemistry in 2023 reported that 2-penten-1-ol exhibits significant activity against several strains of bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). This finding highlights the compound's potential as a lead molecule for the development of novel antimicrobial agents.

Beyond its antimicrobial properties, 2-penten-1-ol has also been studied for its role in enhancing drug delivery systems. Research conducted at the University of California, Los Angeles (UCLA) demonstrated that 2-penten-1-ol can improve the permeability of certain drugs through biological membranes, thereby enhancing their bioavailability. This property is particularly important for drugs that have poor solubility or are poorly absorbed by the body. The study, published in the Journal of Pharmaceutical Sciences, suggests that 2-penten-1-ol could be used as an adjuvant to improve the efficacy of existing medications.

In the cosmetics industry, 2-penten-1-ol is valued for its skin conditioning properties. It is often used as an ingredient in skincare products such as moisturizers, lotions, and serums. The compound's ability to hydrate and soothe the skin makes it an attractive choice for formulators looking to develop products that address dryness and irritation. A study published in the Cosmetics Journal in 2023 found that formulations containing 2-penten-1-ol significantly improved skin hydration levels and reduced transepidermal water loss (TEWL), indicating its effectiveness as a moisturizing agent.

The chemical synthesis of 2-penten-1-ol has been extensively studied to optimize production methods and reduce costs. One common synthetic route involves the hydration of 2-pentene using sulfuric acid as a catalyst. However, recent advancements in green chemistry have led to the development of more environmentally friendly methods. For example, researchers at the University of Cambridge have developed a catalytic process using metal-free catalysts that significantly reduces waste generation and energy consumption. This approach not only makes the production of 2-penten-1-ol more sustainable but also aligns with global efforts to reduce the environmental impact of chemical manufacturing.

The safety profile of 2-penten-1-ol has been extensively evaluated through various toxicological studies. These studies have shown that the compound is generally safe for use in consumer products when used at appropriate concentrations. However, it is important to follow recommended guidelines and conduct thorough risk assessments to ensure safe handling and application. The European Chemicals Agency (ECHA) has classified 2-penten-1-ol as non-hazardous under current regulations, but users should still exercise caution and adhere to best practices.

In conclusion, 2-Penten-1-ol (CAS No. 20273-24-9) is a multifunctional compound with a wide range of applications across different industries. Its unique chemical properties make it valuable in pharmaceuticals, cosmetics, and chemical synthesis. Recent research has further expanded our understanding of its potential benefits and uses, highlighting its importance as a key ingredient in various formulations. As ongoing studies continue to explore new applications and improve production methods, 2-penten-1-ol is likely to remain a significant player in the chemical industry.

• 7786-44-9(2,6-Nonadien-1-ol)
• 928-94-9(cis-2-Hexen-1-ol)
• 1576-95-0(cis-2-Penten-1-ol)
• 28069-72-9(trans,cis-2,6-Nonadien-1-ol)
• 2305-21-7(2-Hexen-1-ol)
• 928-95-0((E)-Hex-2-en-1-ol)
• 1576-96-1((2E)-pent-2-en-1-ol)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)