Cas no 20186-22-5 (6H-[1,3]Dioxolo[5,6]benzofuro[3,2-c][1]benzopyran-6a(12aH)-ol,3-methoxy-, (6aS,12aS)-)
6H-[1,3]Dioxolo[5,6]benzofuro[3,2-c][1]benzopyran-6a(12aH)-ol,3-methoxy-, (6aS,12aS)- Chemical and Physical Properties
Names and Identifiers
-
- 6H-[1,3]Dioxolo[5,6]benzofuro[3,2-c][1]benzopyran-6a(12aH)-ol,3-methoxy-, (6aS,12aS)-
- Pisatin
- PISATIN(P)
- (-)-Pisatin
- (6aS,12aS)-3-Methoxy-6H-[1,3]Dioxolo[5,6]benzofuro[3,2-c][1]benzopyran-6a(12aH)-ol
- [ "" ]
- 6H-(1,3)DIOXOLO(5,6)BENZOFURO(3,2-C)(1)BENZOPYRAN-6A(12AH)-OL, 3-METHOXY-, (6AS,12AS)-
- 498E2M1IW2
- FS-8595
- (+/-)-Pisatin
- 6H-(1,3)Dioxolo(5,6)benzofuro(3,2-C)(1)benzopyran-6a(12ah)-ol, 3-methoxy-, (6aR,12aR)-rel-
- GLXC-17005
- N4PE9U3RE5
- (1S,12S)-16-methoxy-5,7,11,19-tetraoxapentacyclo[10.8.0.02,10.04,8.013,18]icosa-2,4(8),9,13(18),14,16-hexaen-1-ol
- 20186-22-5
- 6H-(1,3)Dioxolo(5,6)benzofuro(3,2-C)(1)benzopyran-6a(12ah)-ol, 3-methoxy-, cis-(+/-)-
- 6H-(1,3)Dioxolo(5,6)benzofuro(3,2-c)(1)benzopyran-6a(12aH)-ol, 3-methoxy-, (6aS-cis)-
- UNII-498E2M1IW2
- 3187-47-1
- (6aS,12aS)-3-Methoxy-6H-[1,3]dioxolo[4',5':5,6]benzofuro[3,2-c]chromen-6a(12aH)-ol
- DTXSID10942240
- 3-Methoxy-6H,9H-[1,3]dioxolo[5,6][1]benzofuro[3,2-c][1]benzopyran-6a(12aH)-ol
- (S,S)-Pisatin
- PISATIN, (-)-
- Pisatin, (+/-)-
- 6H-[1,3]Dioxolo[5,6]benzofuro[3,2-c][1]benzopyran-6a(12aH)-ol, 3-methoxy-, (6aS,12aS)-
- AKOS040762201
- Q21099606
- UNII-N4PE9U3RE5
-
- Inchi: 1S/C17H14O6/c1-19-9-2-3-10-12(4-9)20-7-17(18)11-5-14-15(22-8-21-14)6-13(11)23-16(10)17/h2-6,16,18H,7-8H2,1H3/t16-,17+/m0/s1
- InChI Key: LZMRDTLRSDRUSU-DLBZAZTESA-N
- SMILES: O1C2C=C3C(=CC=2[C@@]2(COC4C=C(C=CC=4[C@H]12)OC)O)OCO3
Computed Properties
- Exact Mass: 314.07900
- Monoisotopic Mass: 314.079038
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 6
- Heavy Atom Count: 23
- Rotatable Bond Count: 1
- Complexity: 472
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 2
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 66.4
- XLogP3: 1.7
Experimental Properties
- Color/Form: Powder
- Density: 1.501
- Boiling Point: 483°Cat760mmHg
- Flash Point: 245.9°C
- Refractive Index: 1.674
- PSA: 66.38000
- LogP: 2.13760
- Vapor Pressure: 0.0±1.3 mmHg at 25°C
6H-[1,3]Dioxolo[5,6]benzofuro[3,2-c][1]benzopyran-6a(12aH)-ol,3-methoxy-, (6aS,12aS)- Security Information
- Hazard Statement: H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Warning Statement: P264+P280+P305+P351+P338+P337+P313
- Safety Instruction: H303+H313+H333
- Storage Condition:Store at 4 ℃, better at -4 ℃
6H-[1,3]Dioxolo[5,6]benzofuro[3,2-c][1]benzopyran-6a(12aH)-ol,3-methoxy-, (6aS,12aS)- Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI TAO SHU Biotechnology Co., Ltd. | TN4800-1 mg |
Pisatin |
20186-22-5 | 1mg |
¥2035.00 | 2022-04-26 | ||
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | P82350-5mg |
Pisatin |
20186-22-5 | 5mg |
¥4000.0 | 2021-09-08 | ||
| TargetMol Chemicals | TN4800-5 mg |
Pisatin |
20186-22-5 | 98% | 5mg |
¥ 11,620 | 2023-07-10 | |
| TargetMol Chemicals | TN4800-1 mL * 10 mM (in DMSO) |
Pisatin |
20186-22-5 | 98% | 1 mL * 10 mM (in DMSO) |
¥ 13980 | 2023-09-15 | |
| TargetMol Chemicals | TN4800-5mg |
Pisatin |
20186-22-5 | 5mg |
¥ 11620 | 2024-07-19 | ||
| A2B Chem LLC | AB03366-1mg |
Pisatin |
20186-22-5 | 98% | 1mg |
$575.00 | 2024-04-20 | |
| MedChemExpress | HY-N3045-1mg |
(S,S)-Pisatin |
20186-22-5 | ≥98.0% | 1mg |
¥5400 | 2024-07-20 | |
| TargetMol Chemicals | TN4800-1 ml * 10 mm |
Pisatin |
20186-22-5 | 1 ml * 10 mm |
¥ 13980 | 2024-07-19 | ||
| Ambeed | A266790-5mg |
(6aS,12aS)-3-Methoxy-6H-[1,3]dioxolo[4',5':5,6]benzofuro[3,2-c]chromen-6a(12aH)-ol |
20186-22-5 | 98+% | 5mg |
$800.0 | 2025-02-27 | |
| A2B Chem LLC | AB03366-5mg |
Pisatin |
20186-22-5 | 98% | 5mg |
$1665.00 | 2024-04-20 |
6H-[1,3]Dioxolo[5,6]benzofuro[3,2-c][1]benzopyran-6a(12aH)-ol,3-methoxy-, (6aS,12aS)- Suppliers
6H-[1,3]Dioxolo[5,6]benzofuro[3,2-c][1]benzopyran-6a(12aH)-ol,3-methoxy-, (6aS,12aS)- Related Literature
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Related Categories
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Additional information on 6H-[1,3]Dioxolo[5,6]benzofuro[3,2-c][1]benzopyran-6a(12aH)-ol,3-methoxy-, (6aS,12aS)-
Introduction to 6H-[1,3]Dioxolo[5,6]benzofuro[3,2-c][1]benzopyran-6a(12aH)-ol, 3-methoxy-, (6aS,12aS)- (CAS No. 20186-22-5)
6H-[1,3]Dioxolo[5,6]benzofuro[3,2-c][1]benzopyran-6a(12aH)-ol, 3-methoxy-, (6aS,12aS)- (CAS No. 20186-22-5) is a complex organic compound that has garnered significant attention in the fields of medicinal chemistry and pharmaceutical research. This compound, often referred to by its systematic name or CAS number, belongs to a class of molecules known as benzopyrans. Its unique structural features and potential biological activities make it a valuable candidate for various applications in drug discovery and development.
The molecular structure of 6H-[1,3]Dioxolo[5,6]benzofuro[3,2-c][1]benzopyran-6a(12aH)-ol, 3-methoxy-, (6aS,12aS)- is characterized by a fused ring system that includes a dioxolane ring, a benzofuran ring, and a benzopyran ring. The presence of the 3-methoxy group and the specific stereochemistry (6aS,12aS) contribute to its unique chemical properties and biological activities. This compound has been studied for its potential as a lead molecule in the development of new therapeutic agents.
Recent research has highlighted the diverse biological activities of 6H-[1,3]Dioxolo[5,6]benzofuro[3,2-c][1]benzopyran-6a(12aH)-ol, 3-methoxy-, (6aS,12aS)-. Studies have shown that this compound exhibits significant antioxidant properties, which are crucial for protecting cells from oxidative stress and damage. Oxidative stress is implicated in various diseases such as cancer, neurodegenerative disorders, and cardiovascular diseases. Therefore, compounds with strong antioxidant capabilities are of great interest in the development of preventive and therapeutic strategies.
In addition to its antioxidant properties, 6H-[1,3]Dioxolo[5,6]benzofuro[3,2-c][1]benzopyran-6a(12aH)-ol, 3-methoxy-, (6aS,12aS)- has been investigated for its anti-inflammatory effects. Inflammation is a key factor in many chronic diseases and conditions. Research has demonstrated that this compound can inhibit the production of pro-inflammatory cytokines and reduce inflammation in various cellular models. These findings suggest that it could be a promising candidate for the treatment of inflammatory diseases.
The potential anticancer properties of 6H-[1,3]Dioxolo[5,6]benzofuro[3,2-c][1]benzopyran-6a(12aH)-ol, 3-methoxy-, (6aS,12aS)- have also been explored. Studies have shown that it can induce apoptosis in cancer cells and inhibit tumor growth in vitro and in vivo. The mechanism of action appears to involve the modulation of signaling pathways that are critical for cell survival and proliferation. These findings open up new avenues for the development of novel anticancer drugs.
Beyond its direct biological activities, 6H-[1,3]Dioxolo[5,6]benzofuro[3,2-c][1]benzopyran-6a(12aH)-ol, 3-methoxy-, (6aS,12aS)- has also been studied for its potential as a scaffold for drug design. The unique structural features of this compound make it an attractive starting point for the synthesis of derivatives with enhanced biological activities or improved pharmacological properties. Researchers have used this compound as a template to develop new molecules with optimized potency and selectivity.
The synthesis of 6H-[1,3]Dioxolo[5,6]benzofuro[3,2-c][1]benzopyran-6a(12aH)-ol, 3-methoxy-, (6aS,12aS)- involves multi-step reactions that require careful control of reaction conditions to achieve the desired stereochemistry and purity. Recent advancements in synthetic chemistry have led to more efficient and scalable methods for producing this compound. These improvements have facilitated its use in large-scale studies and preclinical evaluations.
In conclusion, 6H-[1,3]Dioxolo[5,6]benzofuro[3,2-c][1]benzopyran-6a(12aH)-ol, 3-methoxy-, (6aS,12aS)- (CAS No. 20186-22-5) is a promising compound with a wide range of potential applications in medicinal chemistry and pharmaceutical research. Its unique structural features and diverse biological activities make it an attractive candidate for further investigation and development as a therapeutic agent. Ongoing research continues to uncover new insights into its mechanisms of action and potential clinical uses.
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