Cas no 19883-41-1 (H-D-Phg-OMe.HCl)

H-D-Phg-OMe·HCl (Methyl (R)-2-phenylglycinate hydrochloride) is a chiral amino acid ester derivative widely used in peptide synthesis and pharmaceutical research. Its key advantages include high chemical purity and stability, making it suitable for precise synthetic applications. The hydrochloride salt form enhances solubility in polar solvents, facilitating reactions in aqueous or mixed-phase systems. As a building block, it offers efficient incorporation of phenylglycine residues into peptide chains, enabling the study of structure-activity relationships. The methyl ester group provides a reactive handle for further modifications, while the chiral center ensures stereochemical control in asymmetric synthesis. This compound is particularly valuable in medicinal chemistry for developing peptidomimetics and bioactive molecules.
H-D-Phg-OMe.HCl structure
H-D-Phg-OMe.HCl structure
Product Name:H-D-Phg-OMe.HCl
CAS No:19883-41-1
MF:C9H12ClNO2
MW:201.650081634521
MDL:MFCD00137487
CID:51417
PubChem ID:24858635
Update Time:2025-10-28

H-D-Phg-OMe.HCl Chemical and Physical Properties

Names and Identifiers

    • (R)-Methyl 2-amino-2-phenylacetate hydrochloride
    • D-PHENYLGLYCINE METHYL ESTER HYDROCHLORIDE
    • D-Phenylalanine Methyl ester hydrochloride
    • D-(-)-2-Phenylglycine Methyl Ester Hydrochloride
    • H-D-PHG-OME HCL
    • D-phenylglycine methyl ester ·HCl
    • H-D-Phg-OMe.HCl
    • (R)-(-)-2-Phenylglycine methyl ester hydrochloride
    • D-Phg-OMe.HCl
    • methyl (2R)-2-amino-2-phenylacetate,hydrochloride
    • Methyl α-aminophenylacetate HCl
    • (R)-(?)-2-Phenylglycine methyl ester hydrochloride
    • (R)-PGME hydrochloride
    • <small>D<
    • D-Phenylycine Methyl Ester Hydrichloride
    • D-Phg-OMe*HCl
    • (R)-(-)-2-Amino-2-phenylacetic Acid Methyl Ester Hydrochloride
    • H-D-Phg-OMe·HCl
    • Methyl (R)-(-)-2-Amino-2-phenylacetate Hydrochloride
    • Methyl (R)-aminophenylacetate hydrochloride
    • T0400-4069
    • D-Peg-Oe.H Cl
    • H-D-Phg · OCH3 · HCl
    • Cephalexin Impurity 1
    • D-PHENYLGLYCINE-OME HCL
    • D-Phenylglycine Methyl Ester HCl
    • R-Phenyl Glycine methyl ester HCL
    • methyl 2-azanyl-2-phenyl-ethanoate
    • (R)-2-Phenylglycine Methyl Ester Hydrochloride
    • D-alpha-Phenylglycine methyl ester hydrochloride
    • PubChem19021
    • PubChem10946
    • Methyl (2R)-amino(phenyl)acetate hydrochloride
    • DTHMTBUWTGVEFG-DDWIOCJRSA-N
    • A-Phenylglycine methyl ester hydrochloride
    • AKOS015846308
    • (R)-2-PhenylglycineMethylEsterHydrochloride
    • W-107665
    • EN300-657365
    • E70004
    • Methyl (R)-2-amino-2-phenylacetate hydrochloride
    • [(1R)-2-Methoxy-2-oxo-1-phenylethyl]azanium;chloride
    • SCHEMBL1143309
    • P2592
    • METHYL (2R)-2-AMINO-2-PHENYLACETATE HYDROCHLORIDE
    • D-
    • AKOS015903224
    • NS00082922
    • (R)-methyl 2-amino-2-phenylacetate, hydrochloride salt
    • H-D-Phg-OMe hydrochloride
    • HY-W014824
    • MFCD00137487
    • SY020988
    • (R)-2-PHENYLGLYCINE METHYL ESTER HCl
    • (R)-(-)-2-Phenylglycine methyl ester hydrochloride, >=95%
    • Benzeneacetic acid, a-amino-, methyl ester, hydrochloride, (aR)-
    • CS-W015540
    • methyl (2R)-2-amino-2-phenylacetate;hydrochloride
    • AM20060537
    • 19883-41-1
    • D-(-)-ALPHA-PHENYLGLYCINE METHYL ESTER HYDROCHLORIDE;DPGME
    • MDL: MFCD00137487
    • Inchi: 1S/C9H11NO2.ClH/c1-12-9(11)8(10)7-5-3-2-4-6-7;/h2-6,8H,10H2,1H3;1H/t8-;/m1./s1
    • InChI Key: DTHMTBUWTGVEFG-DDWIOCJRSA-N
    • SMILES: Cl.O(C)C([C@@H](C1C=CC=CC=1)N)=O
    • BRN: 3915654

Computed Properties

  • Exact Mass: 201.05600
  • Monoisotopic Mass: 165.078979
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 3
  • Complexity: 153
  • Covalently-Bonded Unit Count: 2
  • Defined Atom Stereocenter Count: 1
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 52.3
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: nothing

Experimental Properties

  • Color/Form: Not determined
  • Density: 1.1260
  • Melting Point: 189-191?°C (lit.)
  • Boiling Point: 238.9℃ at 760 mmHg
  • Flash Point: 104.7°C
  • PSA: 52.32000
  • LogP: 2.36170
  • Specific Rotation: -118 o (c=1 in H2O)
  • Optical Activity: [α]20/D ?118°, c =?1 in H2O
  • Solubility: Not determined

H-D-Phg-OMe.HCl Security Information

  • Symbol: GHS07
  • Signal Word:Warning
  • Hazard Statement: H319
  • Warning Statement: P305+P351+P338
  • Hazardous Material transportation number:NONH for all modes of transport
  • WGK Germany:3
  • Hazard Category Code: 36
  • Safety Instruction: S26; S36/37
  • Hazardous Material Identification: Xi
  • Risk Phrases:R36
  • Storage Condition:Store at 4°C,-4At ℃Store…Better

H-D-Phg-OMe.HCl Customs Data

  • HS CODE:29224999

H-D-Phg-OMe.HCl Pricemore >>

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H-D-Phg-OMe.HCl Production Method

H-D-Phg-OMe.HCl Suppliers

Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:19883-41-1)(R)-(-)-2-苯甘氨酸甲酯鹽酸鹽
Order Number:LE8710834;LE25979571;LE14864
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:47
Price ($):discuss personally

Additional information on H-D-Phg-OMe.HCl

Introduction to H-D-Phg-OMe.HCl (CAS No. 19883-41-1)

H-D-Phg-OMe.HCl, with the Chemical Abstracts Service (CAS) number 19883-41-1, is a synthetic compound that has garnered significant attention in the fields of medicinal chemistry and pharmaceutical research. This compound, formally known as H-D-Phenylglycine Methyl Ester Hydrochloride, is a derivative of phenylglycine, an amino acid analog that plays a crucial role in the development of various therapeutic agents.

The structure of H-D-Phg-OMe.HCl consists of a phenylglycine moiety with a methyl ester group and a hydrochloride salt. This unique chemical composition imparts specific properties that make it valuable in the design and synthesis of peptides and peptidomimetics. The presence of the methyl ester group enhances the solubility and stability of the compound, while the hydrochloride salt form ensures its suitability for various pharmaceutical applications.

Recent advancements in the field have highlighted the potential of H-D-Phg-OMe.HCl in several areas of research. One notable application is its use as a building block in the synthesis of bioactive peptides. These peptides are designed to mimic natural peptides and proteins, which can have therapeutic effects in treating various diseases. For instance, studies have shown that peptides containing H-D-Phg-OMe.HCl can exhibit enhanced biological activity and improved pharmacokinetic properties compared to their natural counterparts.

In addition to its role in peptide synthesis, H-D-Phg-OMe.HCl has also been explored for its potential in drug delivery systems. The compound's ability to form stable complexes with other molecules makes it an attractive candidate for developing targeted drug delivery mechanisms. Research has demonstrated that incorporating H-D-Phg-OMe.HCl into drug delivery vehicles can enhance the efficacy and reduce the side effects of therapeutic agents, particularly in cancer treatment and other chronic conditions.

The physicochemical properties of H-D-Phg-OMe.HCl have been extensively characterized. It is a white crystalline solid with a melting point ranging from 165°C to 167°C. The compound is soluble in common organic solvents such as methanol, ethanol, and dimethyl sulfoxide (DMSO), making it easy to handle and process in laboratory settings. Its stability under various conditions, including pH and temperature, has been well-documented, ensuring its reliability in both research and industrial applications.

The safety profile of H-D-Phg-OMe.HCl is another critical aspect that has been thoroughly investigated. Toxicological studies have shown that the compound exhibits low toxicity when administered at therapeutic doses. However, as with any chemical substance, proper handling and storage protocols should be followed to ensure safety in laboratory environments.

In conclusion, H-D-Phg-OMe.HCl (CAS No. 19883-41-1) is a versatile compound with significant potential in medicinal chemistry and pharmaceutical research. Its unique chemical structure and favorable physicochemical properties make it an invaluable tool for developing novel therapeutic agents and drug delivery systems. Ongoing research continues to uncover new applications for this compound, further solidifying its importance in the scientific community.

Recommended suppliers
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:19883-41-1)(R)-(-)-2-苯甘氨酸甲酯鹽酸鹽
LE8710834;LE25979571;LE14864
Purity:99%/99%/99%
Quantity:25KG,200KG,1000KG/25KG,200KG,1000KG/25KG,200KG,1000KG
Price ($):Inquiry/Inquiry/Inquiry
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