Cas no 19868-85-0 (1-methyl-4-nitro-1H-pyrazol-5-amine)

1-Methyl-4-nitro-1H-pyrazol-5-amine is a nitro-substituted pyrazole derivative with potential applications in pharmaceutical and agrochemical research. Its structure features a reactive nitro group at the 4-position and an amine group at the 5-position, making it a versatile intermediate for synthesizing heterocyclic compounds. The methyl group at the 1-position enhances stability and influences reactivity patterns. This compound is particularly valuable in medicinal chemistry for developing bioactive molecules due to its ability to participate in condensation and substitution reactions. Its well-defined chemical properties and consistent purity make it suitable for exploratory studies in drug discovery and material science.
1-methyl-4-nitro-1H-pyrazol-5-amine structure
19868-85-0 structure
Product Name:1-methyl-4-nitro-1H-pyrazol-5-amine
CAS No:19868-85-0
MF:C4H6N4O2
MW:142.11603975296
CID:123815
PubChem ID:588382
Update Time:2025-11-02

1-methyl-4-nitro-1H-pyrazol-5-amine Chemical and Physical Properties

Names and Identifiers

    • 1H-Pyrazol-5-amine,1-methyl-4-nitro-
    • 1H-Pyrazol-5-amine,1-methyl-4-nitro-(9CI)
    • 1-methyl-4-nitro-1H-pyrazol-5-amine
    • 5-Amino-1-methyl-4-nitropyrazole
    • SCHEMBL8385965
    • MFCD00466311
    • AKOS006342723
    • CS-0230870
    • 1-Methyl-4-nitro-1H-pyrazol-5-amine #
    • Z1429880575
    • EN300-105948
    • 2-methyl-4-nitropyrazol-3-amine
    • AKOS000666881
    • 19868-85-0
    • 1H-Pyrazol-5-aMine, 1-Methyl-4-nitro-
    • Inchi: 1S/C4H6N4O2/c1-7-4(5)3(2-6-7)8(9)10/h2H,5H2,1H3
    • InChI Key: YKUPMZUMSWRWPM-UHFFFAOYSA-N
    • SMILES: [O-][N+](C1C=NN(C)C=1N)=O

Computed Properties

  • Exact Mass: 142.04918
  • Monoisotopic Mass: 142.049
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 0
  • Complexity: 145
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 0.3
  • Topological Polar Surface Area: 89.7?2

Experimental Properties

  • PSA: 86.98

1-methyl-4-nitro-1H-pyrazol-5-amine Security Information

1-methyl-4-nitro-1H-pyrazol-5-amine Pricemore >>

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Additional information on 1-methyl-4-nitro-1H-pyrazol-5-amine

Comprehensive Guide to 1-Methyl-4-nitro-1H-pyrazol-5-amine (CAS No. 19868-85-0): Properties, Applications, and Market Insights

1-Methyl-4-nitro-1H-pyrazol-5-amine (CAS No. 19868-85-0) is a specialized organic compound that has garnered significant attention in pharmaceutical and agrochemical research. This nitro-substituted pyrazole derivative is known for its unique chemical properties, making it a valuable intermediate in the synthesis of various bioactive molecules. With the increasing demand for novel heterocyclic compounds in drug discovery, 1-methyl-4-nitro-1H-pyrazol-5-amine has emerged as a key building block for researchers.

The molecular structure of 1-methyl-4-nitro-1H-pyrazol-5-amine features a pyrazole ring system with methyl and nitro functional groups at positions 1 and 4 respectively, and an amino group at position 5. This specific arrangement contributes to its reactivity and makes it particularly useful in medicinal chemistry applications. Recent studies have highlighted its potential in developing anti-inflammatory agents and antimicrobial compounds, addressing current global health challenges.

In the pharmaceutical industry, 1-methyl-4-nitro-1H-pyrazol-5-amine serves as a crucial intermediate for the synthesis of various drug candidates. Its versatility allows for modifications that can lead to compounds with improved bioavailability and target specificity. Researchers are particularly interested in its application for developing treatments for chronic diseases, which aligns with current healthcare trends focusing on personalized medicine and targeted therapies.

The agrochemical sector has also shown growing interest in pyrazole derivatives like 1-methyl-4-nitro-1H-pyrazol-5-amine. These compounds have demonstrated potential in creating new generations of crop protection agents with enhanced efficacy and reduced environmental impact. As sustainable agriculture becomes a global priority, the demand for such innovative chemical solutions continues to rise.

From a synthetic chemistry perspective, 1-methyl-4-nitro-1H-pyrazol-5-amine offers several advantages. Its well-defined reactivity profile allows for controlled transformations, making it a favorite among synthetic organic chemists. The compound's stability under various conditions contributes to its utility in multi-step synthesis, particularly in the development of heterocyclic drug candidates.

Market analysis indicates steady growth in the demand for specialty pyrazole compounds, with 1-methyl-4-nitro-1H-pyrazol-5-amine being no exception. The compound's applications in both pharmaceutical and agricultural sectors contribute to its commercial value. Current trends show increasing research activities focused on nitro-substituted heterocycles, positioning this compound as a significant player in the fine chemicals market.

Quality control and characterization of 1-methyl-4-nitro-1H-pyrazol-5-amine are critical aspects of its production and application. Advanced analytical techniques such as HPLC, NMR spectroscopy, and mass spectrometry are routinely employed to ensure purity and confirm structural integrity. These quality assurance measures are particularly important given the compound's use in sensitive applications like drug development.

The future outlook for 1-methyl-4-nitro-1H-pyrazol-5-amine appears promising, with ongoing research exploring new applications and synthetic routes. As the scientific community continues to investigate nitrogen-containing heterocycles, this compound is likely to maintain its relevance in various chemical industries. Its potential contributions to addressing current challenges in healthcare and agriculture make it a compound worth watching in the coming years.

For researchers and industry professionals working with pyrazole derivatives, understanding the properties and applications of 1-methyl-4-nitro-1H-pyrazol-5-amine is essential. The compound's unique characteristics offer numerous possibilities for innovation in drug design and agrochemical development, making it a valuable asset in the toolkit of modern chemists.

In conclusion, 1-methyl-4-nitro-1H-pyrazol-5-amine (CAS No. 19868-85-0) represents an important class of nitro-substituted pyrazoles with diverse applications across multiple industries. Its role as a building block in medicinal chemistry and its potential in sustainable agriculture highlight its significance in contemporary chemical research and development.

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