• 1. Fate of single walled carbon nanotubes in wetland ecosystems?
  Joseph H. Bisesi,Tara Sabo-Attwood Environ. Sci.: Nano, 2014,1, 574-583
• 2. Exceptionally high temperature spin crossover in amide-functionalised 2,6-bis(pyrazol-1-yl)pyridine iron(ii) complex revealed by variable temperature Raman spectroscopy and single crystal X-ray diffraction?
  Max Attwood,Hiroki Akutsu,Lee Martin,Toby J. Blundell,Pierre Le Maguere,Scott S. Turner Dalton Trans., 2021,50, 11843-11851
• 3. Excellent kinetics of single-phase Gd-doped ceria fuel electrodes in solid oxide cells?
  Andreas Nenning,Manuel Holzmann,Jürgen Fleig,Alexander K. Opitz Mater. Adv., 2021,2, 5422-5431
• 4. Emergence of microfluidic wearable technologies
  Joo Chuan Yeo,Kenry Lab Chip, 2016,16, 4082-4090
• 5. Fe3O4 nanoclusters highly dispersed on a porous graphene support as an additive for improving the hydrogen storage properties of LiBH4?
  Guang Xu,Wei Zhang,Ying Zhang,Xiaoxia Zhao,Ping Wen,Di Ma RSC Adv., 2018,8, 19353-19361

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Halobenzenes Iodobenzenes
• Other Chemical Reagents

Introduction to 1,3-Dibromo-2-iodobenzene (CAS No. 19821-80-8)

1,3-Dibromo-2-iodobenzene, with the CAS number 19821-80-8, is a versatile organic compound that has garnered significant attention in the fields of chemistry, biochemistry, and pharmaceutical research. This compound is characterized by its unique molecular structure, which includes two bromine atoms and one iodine atom substituted on a benzene ring. The presence of these halogen atoms imparts specific chemical properties and reactivity, making it a valuable intermediate in various synthetic pathways.

The molecular formula of 1,3-Dibromo-2-iodobenzene is C₆H₃Br₂I, and its molecular weight is 344.76 g/mol. The compound is a white to off-white solid at room temperature and has a melting point of approximately 95°C. Its solubility in water is low, but it is soluble in common organic solvents such as dichloromethane, acetone, and ethanol. These physical properties make it suitable for use in a wide range of chemical reactions and processes.

In the context of synthetic chemistry, 1,3-Dibromo-2-iodobenzene serves as an important building block for the synthesis of more complex molecules. Its halogenated benzene ring provides multiple reactive sites that can be selectively functionalized through various chemical transformations. For instance, the bromine and iodine substituents can be readily converted into other functional groups such as amines, alcohols, or carboxylic acids using well-established methodologies such as nucleophilic substitution and cross-coupling reactions.

The versatility of 1,3-Dibromo-2-iodobenzene has been leveraged in the development of novel pharmaceuticals and bioactive compounds. Recent studies have explored its potential as a precursor for the synthesis of drugs targeting specific biological pathways. For example, researchers at the University of California have utilized this compound to synthesize a series of potent inhibitors of protein kinases, which are key enzymes involved in cellular signaling and disease progression. These inhibitors have shown promising results in preclinical studies for treating various cancers and inflammatory diseases.

In addition to its applications in drug discovery, 1,3-Dibromo-2-iodobenzene has also found utility in materials science and nanotechnology. The compound can be incorporated into polymers or used as a ligand in metal complexes to create materials with unique optical and electronic properties. For instance, a study published in the Journal of Materials Chemistry demonstrated that 1,3-Dibromo-2-iodobenzene-based polymers exhibit enhanced photoluminescence and stability under various environmental conditions, making them suitable for use in organic light-emitting diodes (OLEDs) and other optoelectronic devices.

The safety and handling of 1,3-Dibromo-2-iodobenzene are critical considerations for researchers working with this compound. While it is not classified as a hazardous material under most regulatory frameworks, proper precautions should be taken to avoid exposure to skin or inhalation of vapors. It is recommended to handle the compound in a well-ventilated area or fume hood and to use appropriate personal protective equipment (PPE) such as gloves and safety goggles.

In conclusion, 1,3-Dibromo-2-iodobenzene (CAS No. 19821-80-8) is a multifaceted compound with significant potential in various scientific disciplines. Its unique chemical structure and reactivity make it an invaluable tool for synthetic chemists, pharmaceutical researchers, and materials scientists alike. Ongoing research continues to uncover new applications and properties of this compound, further solidifying its importance in modern scientific research.

• 62131-93-5(Naphthalene, 2,6-dibromo-3,7-diiodo-)
• 21521-51-7(2,4,6-Tribromoiodobenzene)
• 96843-23-1(Benzene, 1,5-dibromo-2,4-diiodo-)
• 19393-94-3(2,4-Dibromo-1-iodobenzene)
• 102153-44-6(2-Bromo-3-iodonaphthalene)
• 89284-52-6(1,4-Dibromo-2-iodobenzene)
• 583-55-1(2-Bromoiodobenzene)
• 533-55-1(2-Bromo-iodobenzene)
• 57137-98-1(Benzene, pentabromoiodo-)
• 63262-06-6(1,4-Dibromo-2,5-diiodobenzene)