Cas no 19817-88-0 (N-Hexanoyl-D-glucosamine)

N-Hexanoyl-D-glucosamine is a chemically modified derivative of D-glucosamine, where a hexanoyl group is introduced to enhance its lipophilicity and stability. This modification improves its bioavailability and membrane permeability, making it advantageous for applications in cosmetic and pharmaceutical formulations. The compound retains the bioactive properties of glucosamine, such as supporting skin hydration and extracellular matrix synthesis, while offering superior solubility in lipid-based systems. Its amphiphilic nature allows for versatile incorporation into emulsions and delivery systems. N-Hexanoyl-D-glucosamine is particularly valued in anti-aging and moisturizing products due to its ability to promote collagen production and maintain skin barrier function.
N-Hexanoyl-D-glucosamine structure
N-Hexanoyl-D-glucosamine structure
Product Name:N-Hexanoyl-D-glucosamine
CAS No:19817-88-0
MF:C12H23NO6
MW:277.314124345779
MDL:MFCD00059806
CID:854890
PubChem ID:87570564
Update Time:2025-06-14

N-Hexanoyl-D-glucosamine Chemical and Physical Properties

Names and Identifiers

    • N-Hexanoyl-D-glucosamine
    • D-Glucose, 2-deoxy-2-[(1-oxohexyl)amino]-
    • 2-DEOXY-2-HEXANAMIDO-D-GLUCOPYRANOSE
    • 2-hexanoylamino-2-deoxy-D-glucose
    • 2-Hexanoylamino-2-desoxy-D-glucose
    • Hexanoylglucosamine
    • N-Caproyl-D-glucosamine
    • N-D-Glucose-2-yl-hexamid
    • N-((2R,3R,4S,5R)-3,4,5,6-Tetrahydroxy-1-oxohexan-2-yl)hexanamide
    • N-(3,4,5,6-Tetrahydroxy-1-oxohexan-2-yl)hexanamide
    • N-[(2R,3R,4S,5R)-3,4,5,6-tetrahydroxy-1-oxohexan-2-yl]hexanamide
    • 19817-88-0
    • AKOS027320137
    • CS-0214565
    • HY-W145573
    • QLZZYPWIRVQENX-LUTQBAROSA-N
    • SCHEMBL5157353
    • AS-64975
    • MDL: MFCD00059806
    • Inchi: 1S/C12H23NO6/c1-2-3-4-5-10(17)13-8(6-14)11(18)12(19)9(16)7-15/h6,8-9,11-12,15-16,18-19H,2-5,7H2,1H3,(H,13,17)/t8-,9+,11+,12+/m0/s1
    • InChI Key: QLZZYPWIRVQENX-LUTQBAROSA-N
    • SMILES: O[C@H]([C@H](C=O)NC(CCCCC)=O)[C@@H]([C@@H](CO)O)O

Computed Properties

  • Exact Mass: 277.15300
  • Monoisotopic Mass: 277.15253745g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 5
  • Hydrogen Bond Acceptor Count: 6
  • Heavy Atom Count: 19
  • Rotatable Bond Count: 10
  • Complexity: 273
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 4
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 127
  • XLogP3: -1.5

Experimental Properties

  • Refractive Index: 98 ° (C=1, Pyridine)
  • PSA: 119.25000
  • LogP: -1.12630

N-Hexanoyl-D-glucosamine Security Information

  • Regulatory Condition Code:Class Q (sugars, alkaloids, antibiotics, hormones)

N-Hexanoyl-D-glucosamine Customs Data

  • HS CODE:2924199090
  • Customs Data:

    China Customs Code:

    2924199090

    Overview:

    2924199090. Other acyclic amides(Including acyclic carbamates)(Including its derivatives and salts). VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to, packing

    Summary:

    2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

N-Hexanoyl-D-glucosamine Pricemore >>

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Additional information on N-Hexanoyl-D-glucosamine

Comprehensive Guide to N-Hexanoyl-D-glucosamine (CAS No. 19817-88-0): Properties, Applications, and Innovations

N-Hexanoyl-D-glucosamine (CAS No. 19817-88-0), a derivative of D-glucosamine, is a bioactive compound gaining significant attention in cosmetic, pharmaceutical, and nutraceutical industries. Its unique molecular structure, combining a hexanoyl fatty acid chain with the amino sugar glucosamine, enhances skin permeability and bioavailability. This article explores its chemical properties, mechanisms of action, and cutting-edge applications, addressing trending queries like "anti-aging benefits of N-Hexanoyl-D-glucosamine" and "how N-Hexanoyl-D-glucosamine boosts hydration."

The compound’s CAS registry number 19817-88-0 ensures precise identification in regulatory and research contexts. Structurally, it modifies D-glucosamine by introducing a hexanoyl group, improving lipid solubility while retaining the parent molecule’s biocompatibility. Studies highlight its role in stimulating hyaluronic acid synthesis, a key factor in addressing "skin barrier repair" and "wrinkle reduction"—topics frequently searched in dermatology forums. Its dual hydrophilic-lipophilic nature makes it ideal for cosmetic formulations, particularly serums and creams targeting dry skin and elasticity loss.

Recent advancements spotlight N-Hexanoyl-D-glucosamine as a sustainable alternative to conventional skin moisturizers. Unlike petrochemical-derived ingredients, it aligns with the "clean beauty movement," a trending consumer preference. Research indicates its synergy with niacinamide and peptides, amplifying effects on collagen production—a hot topic in "skincare ingredient combinations" searches. Additionally, its low irritation potential caters to "sensitive skin solutions," further driving its popularity in K-beauty and medical aesthetics.

In nutraceuticals, N-Hexanoyl-D-glucosamine (CAS 19817-88-0) is explored for joint health, leveraging the chondroprotective properties of glucosamine. Users often search for "bioavailable glucosamine supplements," where this derivative’s enhanced absorption offers a competitive edge. Its preclinical data suggests anti-inflammatory effects, resonating with queries like "natural remedies for osteoarthritis." However, further clinical trials are needed to validate these claims.

From an industrial perspective, N-Hexanoyl-D-glucosamine exemplifies innovation in green chemistry. Manufacturers prioritize enzymatic synthesis to reduce waste, aligning with "eco-friendly production" trends. Analytical techniques like HPLC and NMR ensure purity, critical for meeting ISO standards—a frequent concern in "cosmetic ingredient sourcing" discussions. Regulatory bodies such as the ECHA and FDA classify it as safe for topical use, bolstering its market growth.

Future research directions include optimizing N-Hexanoyl-D-glucosamine’s stability in aqueous formulations and exploring its wound-healing potential. As consumers increasingly seek "science-backed skincare" and "multifunctional ingredients," this compound is poised to expand its applications, from anti-acne products to hair care innovations. Its versatility and safety profile make it a cornerstone in next-generation personal care solutions.

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