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• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Peptides
• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues Peptides

Comprehensive Overview of Methyl (2S)-2-(2S)-2-{(tert-butoxy)carbonylamino}propanamidopropanoate (CAS No. 19794-10-6)

Methyl (2S)-2-(2S)-2-{(tert-butoxy)carbonylamino}propanamidopropanoate (CAS No. 19794-10-6) is a chiral ester compound widely used in pharmaceutical synthesis and organic chemistry research. Its unique stereochemical properties and functional groups make it a valuable intermediate in the production of peptide-based drugs and bioactive molecules. The compound's tert-butoxy carbonyl (Boc) protecting group is particularly noteworthy, as it is a cornerstone in modern peptide synthesis strategies.

In recent years, the demand for chiral intermediates like methyl (2S)-2-(2S)-2-{(tert-butoxy)carbonylamino}propanamidopropanoate has surged due to the growing pharmaceutical industry's focus on enantioselective synthesis. Researchers frequently search for "Boc-protected amino acid derivatives" or "chiral ester applications in drug development," highlighting the compound's relevance in cutting-edge research. The CAS No. 19794-10-6 serves as a critical identifier for scientists sourcing high-purity materials for asymmetric synthesis.

The compound's molecular structure features two stereocenters, making it an excellent candidate for studying diastereoselective reactions—a hot topic in organic chemistry forums. Its methyl ester moiety provides enhanced solubility in organic solvents, a property often discussed in "solubility enhancement strategies for peptide synthesis" queries. Furthermore, the Boc group's stability under basic conditions makes this compound a preferred choice for multi-step syntheses requiring orthogonal protection schemes.

From a synthetic chemistry perspective, methyl (2S)-2-(2S)-2-{(tert-butoxy)carbonylamino}propanamidopropanoate demonstrates remarkable versatility. It can participate in amide coupling reactions, serve as a building block for non-natural amino acids, or undergo selective deprotection for subsequent functionalization. These characteristics align with current trends in "green chemistry approaches to peptide synthesis" and "atom-economical transformations," which dominate contemporary literature searches.

Quality control of CAS No. 19794-10-6 typically involves advanced analytical techniques like chiral HPLC and mass spectrometry, addressing the pharmaceutical industry's emphasis on "analytical method validation for chiral compounds." The compound's shelf stability and storage conditions (typically 2-8°C under inert atmosphere) are frequently queried topics among laboratory technicians handling sensitive intermediates.

In drug discovery pipelines, derivatives of methyl (2S)-2-(2S)-2-{(tert-butoxy)carbonylamino}propanamidopropanoate have shown potential in modulating protein-protein interactions—a trending research area in "targeted cancer therapeutics" and "allosteric drug design." The compound's structural features enable rational design of conformationally constrained peptides, addressing the growing demand for "bioactive peptide mimetics" in medicinal chemistry.

The synthesis scale-up of CAS No. 19794-10-6 presents interesting engineering challenges that intersect with popular searches about "continuous flow chemistry for chiral compounds." Recent process optimization studies have demonstrated efficient routes using enzymatic resolution techniques, reflecting the industry's shift toward "biocatalytic asymmetric synthesis" methodologies.

Regulatory aspects of methyl (2S)-2-(2S)-2-{(tert-butoxy)carbonylamino}propanamidopropanoate comply with major pharmacopeial standards (USP/EP), a crucial consideration for manufacturers responding to "GMP compliance for pharmaceutical intermediates" inquiries. The compound's well-documented safety profile and absence of structural alerts make it suitable for preclinical development stages.

Emerging applications in materials science have expanded interest in CAS No. 19794-10-6, particularly in designing peptide-based biomaterials for tissue engineering—a rapidly growing field generating numerous "smart biomaterial design" searches. The compound's ability to introduce chiral centers into polymeric backbones enables precise control over material properties.

From a commercial availability standpoint, suppliers often highlight methyl (2S)-2-(2S)-2-{(tert-butoxy)carbonylamino}propanamidopropanoate's batch-to-batch consistency and customizable packaging options, addressing frequent procurement questions about "bulk chiral compound suppliers." The global market for such enantiomerically pure building blocks continues to grow annually, driven by increased outsourcing of synthetic steps by pharmaceutical companies.

• 90303-36-9(L-Alanine,N-[N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl]-, monohydrate (9CI))
• 72086-77-2(Alanine, N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl-2-methyl-, methyl ester)
• 62437-47-2(Glycine, N-[N-[N-[N-[N-[(1,1-dimethylethoxy)carbonyl]glycyl]glycyl]glycyl]-L-alanyl]-, methyl ester (9CI))
• 67706-13-2(Glycine, N-[N-[(1,1-dimethylethoxy)carbonyl]-D-alanyl]-, methyl ester)
• 88050-19-5(L-Alanine, N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl-2-methylalanyl-L-alanyl-2-methylalanyl-L-alanyl-L-alanyl-2-methylalanyl-L-alanyl-2-methylalanyl-L-alanyl-L-alanyl-2-methylalanyl-L-alanyl-2-methylalanyl-, methyl ester (9CI))
• 72086-94-3(L-Alanine,N-[N-[N-[N-[N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl]-2-methylalanyl]-L-alanyl]-2-methylalanyl]-, methyl ester)
• 71017-97-5(L-Serine, N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl-, methyl ester)
• 62437-35-8(Glycine,N-[N-[N-[N-[(1,1-dimethylethoxy)carbonyl]glycyl]glycyl]-L-alanyl]-, methylester)
• 62437-32-5(Glycine, N-[N-[N-[(1,1-dimethylethoxy)carbonyl]glycyl]-L-alanyl]-, methylester)
• 62597-83-5(Glycine,N-[N-[N-[N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl]-L-alanyl]-L-alanyl]-,methyl ester)